Gene Information

Name : clpB2 (CULC22_01998)
Accession : YP_004630622.1
Strain : Corynebacterium ulcerans BR-AD22
Genome accession: NC_015683
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease ATP-binding subunit
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 2176156 - 2178813 bp
Length : 2658 bp
Strand : -
Note : ATPases with chaperone activity, ATP-binding subunit

DNA sequence :
ATGTTCGAGCGGTTTACCGATCGTGCACGTCGCGTGATCGTCCTGGCACAGGAAGAAGCGCGCGGCCTTAACCACAATTA
CATCGGCACCGAGCATATTCTGCTCGGACTTATCCATGAGGGTGAGGGTGTTGCTGCAAAGGCCCTCGAATCTATGGGCA
TCTCCCTGGAAGCGGTTCGCCAAGAAGTAGAAGAAATTATCGGACATGGCTCCGAGCCGCCAGTTGGGCATATTCCTTTT
ACCCCACGCGCCAAGAAAGTGCTTGAGCTTTCTCTCCGCGAGGGACTACAGATGGGACACAAGTACATCGGTACTGAGTT
CCTGCTTTTGGGCTTGATCCGTGAAGGTGAAGGCGTTGCTGCTCAGGTGCTGGTCAAACTCGGGGCAGACCTTCCTCGTG
TGCGTCAGCAGGTTATCCAGCTGCTTTCGGGCTACGAAGGCGGAGAGAGCCCAGAAAATAATGAATCAGGCGGCGAAGCC
GTGGGTGCGGGCACAGGTGCAGCACGCGCAGGTCGCGGCAGCGGCGCTGGTGATCGCTCCAACTCCTTGGTGCTGGATCA
ATTCGGTCGAAACCTGACCCAGGCTGCTAAGGACGGCAAGCTGGATCCCGTTGTGGGGCGTGAGAAAGAAATCGAGCGCA
TCATGCAGGTTCTTTCCCGTCGCACCAAGAACAATCCTGTCTTGATCGGTGAGCCCGGCGTGGGTAAGACCGCCGTAGTT
GAAGGCTTGGCGCTAGACATCGTCAACGGCAAGGTGCCCGAGACTCTTAAAGATAAGCAGCTGTACTCCCTAGATCTGGG
TTCCTTGGTTGCAGGATCGCGTTATCGCGGCGACTTTGAGGAACGCCTAAAGAAGGTCCTCAAGGAGATTAACCAGCGCG
GCGACATCATCTTGTTCATCGACGAGATCCATACCCTGGTAGGCGCCGGCGCAGCTGAAGGCGCTATCGATGCTGCCAGC
CTGCTGAAGCCAAAGCTTGCCCGCGGTGAGCTGCAGACCATCGGCGCAACGACTCTCGACGAGTACCGTAAGCACATTGA
AAAGGACGCCGCTCTTGAGCGCCGCTTCCAGCCAGTCAACGTGCCGGAACCAAGCGTGGAGATGACCATTGAGATTCTCA
AGGGCCTGCGTGACCGCTACGAGGCCCACCACCGCGTTTCCATCACGGACGGCGCGCTAGCAGCCGCAGCACAGCTGTCG
GACCGCTACATCAACGACCGCTTCTTACCAGATAAGGCAGTCGACCTTATCGATGAAGCTGGAGCTCGCATGCGTATTCA
GCGCATGACCGCCCCCGAGTCGATCCGTAAGGTTGATGACCGCATCGCAGAGGTGCGCCGGGAAAAGGAAGCCGCGATTG
ATGCGCAGGACTTTGAAAAAGCCGCTGGCTTGCGCGATACCGAGCGGAAGCTGAACGAGGAACGTGCAGAGAAAGAAAAG
CAATGGCGTTCTGGCGATCTGGAAGAGATCGCTGAGGTCGGCGAGGAACAGATCGCGGAAGTTCTGGGCAACTGGACGGG
CATCCCAGTATTCAAGCTGACAGAAGAGGAGTCCTCTCGTCTGCTGCGCATGGAAGATGAGCTACACAAGCGCATCATCG
GCCAAGAGGATGCAGTCAAGGCTGTATCCCGTGCAATTCGCCGTACCCGCGCCGGTCTAAAGGACCCGCGCCGTCCTTCC
GGTTCCTTCATCTTCGCTGGACCATCCGGTGTGGGTAAGACCGAGCTTTCCAAGGCATTGGCTAACTTCCTGTTCGGCGA
TGATGACGCGCTGATCCAGATCGATATGGGCGAGTTCCATGATCGTTTCACCGCTTCACGCCTGTTCGGTGCTCCTCCCG
GATACGTTGGTTATGAGGAAGGCGGCCAGCTCACGGAGAAGGTACGTCGCAAGCCTTTCAGCGTTGTGCTTTTCGACGAA
ATCGAGAAAGCACACAAAGAGATCTACAACACGCTGCTGCAGGTGTTGGAAGACGGACGGCTTACCGACGGCCAAGGCCG
CGTAGTGGACTTCAAGAACACCGTTCTGATCTTCACGTCAAACCTCGGCACGCAGGACATCTCCAAGGCCGTGGGCATGG
GCTTTAGCTCTGTCGGCGAGCATGACGCGGATGGCCAGTACACCCGGATGAAGCAGAAGGTTAACGACGAGCTGAAGAAG
CACTTCCGCCCTGAATTCCTTAACCGCATCGACGAGGTCGTGGTCTTCCACCAGCTCACACAGGACCAGATCGTTCAGAT
GGTGGACCTGCTGGTTGGTCGTGTGTCAAAGGCCCTGGCTCAGAAAGACATGGGCATCGAGCTCACCGAGAAGGCAAAGA
GCCTTTTGGCACGCAGAGGATTCGATCCAGTGTTGGGTGCACGCCCATTGCGTCGTACGATTCAGCGTGAGATCGAGGAC
GCACTCTCCGAGAAGATTCTCTTTGGTGAGGTCGGCGCTGGCGAGATCGTCACAGTAGACGTTGAGGGATGGGATGGCGA
GTCCAAGGAGACGGACAAGGCCACATTCACCTTCGCGCCACGTCCAAAGCCACTGCCAGATTTTGCCACGGAATCTCCCG
AGGTTGTTGAGGCACAGCAGGCTGTGGTCGAGGCAGCGGATAATCCTGAGACGGTTCCCGAAGCTGATTTTGACGTAGAA
GAAGCTAAGGAACAGTAA

Protein sequence :
MFERFTDRARRVIVLAQEEARGLNHNYIGTEHILLGLIHEGEGVAAKALESMGISLEAVRQEVEEIIGHGSEPPVGHIPF
TPRAKKVLELSLREGLQMGHKYIGTEFLLLGLIREGEGVAAQVLVKLGADLPRVRQQVIQLLSGYEGGESPENNESGGEA
VGAGTGAARAGRGSGAGDRSNSLVLDQFGRNLTQAAKDGKLDPVVGREKEIERIMQVLSRRTKNNPVLIGEPGVGKTAVV
EGLALDIVNGKVPETLKDKQLYSLDLGSLVAGSRYRGDFEERLKKVLKEINQRGDIILFIDEIHTLVGAGAAEGAIDAAS
LLKPKLARGELQTIGATTLDEYRKHIEKDAALERRFQPVNVPEPSVEMTIEILKGLRDRYEAHHRVSITDGALAAAAQLS
DRYINDRFLPDKAVDLIDEAGARMRIQRMTAPESIRKVDDRIAEVRREKEAAIDAQDFEKAAGLRDTERKLNEERAEKEK
QWRSGDLEEIAEVGEEQIAEVLGNWTGIPVFKLTEEESSRLLRMEDELHKRIIGQEDAVKAVSRAIRRTRAGLKDPRRPS
GSFIFAGPSGVGKTELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPGYVGYEEGGQLTEKVRRKPFSVVLFDE
IEKAHKEIYNTLLQVLEDGRLTDGQGRVVDFKNTVLIFTSNLGTQDISKAVGMGFSSVGEHDADGQYTRMKQKVNDELKK
HFRPEFLNRIDEVVVFHQLTQDQIVQMVDLLVGRVSKALAQKDMGIELTEKAKSLLARRGFDPVLGARPLRRTIQREIED
ALSEKILFGEVGAGEIVTVDVEGWDGESKETDKATFTFAPRPKPLPDFATESPEVVEAQQAVVEAADNPETVPEADFDVE
EAKEQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 94
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 4e-98 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB2 YP_004630622.1 ATP-dependent Clp protease ATP-binding subunit VFG0079 Protein 0.0 58
clpB2 YP_004630622.1 ATP-dependent Clp protease ATP-binding subunit VFG0080 Protein 8e-152 52