Gene Information

Name : polA1 (CULC22_01188)
Accession : YP_004629817.1
Strain : Corynebacterium ulcerans BR-AD22
Genome accession: NC_015683
Putative virulence/resistance : Unknown
Product : bacteriophage-type DNA polymerase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0749
EC number : 2.7.7.7
Position : 1311914 - 1313899 bp
Length : 1986 bp
Strand : -
Note : DNA polymerase I - 3'-5' exonuclease and polymerase domains

DNA sequence :
ATGCGAACGCTCTCTATCGACATTGAAACCTTCAGCTCCGCCAATATCGCCAAAGGAGGCGCTTATAAATATGCGGCAGC
AGACGATTTCGAAATTCTTCTCTTCGCTTACTCCGTCGATGACAGCCCCGTCACCGTGGTGTCAATCGCCACCGGCGAGA
CCGTACCCGCCGATATTATTTCAGCGCTCACGGACCCTTCGGTGACGAAATATGCGTTCAATGCCCAATTCGAACGAGTC
TGCCTATCCCGATGGTTACAGCAGCAAAGCTTACTACCGAAAGAAGAGTTCATTGACCCAGGCGGTTGGCGATGCACCAT
GGTGTGGTGTGCCTCCATCGGACTGCCGATGTCACTGGACCAAGCTGCGAAAGTTCTCAGCCTGAAAGCCCAAAAAATAT
CCGAAGGTAAAAGTCTTATCCAGTATTTTTGCTTACCGACAAAACCACGAGAGGTCGCCGCCCCGGTATTGTTCGACGCC
TCAGGTATGACCCATCGGAACCACCCACAAACAGCCCCTGAACGCTGGGTGGACTTCATCGAATACAACCGTCGTGACGT
GGAAACCGAGCAAGAAATGCGCACAAAACTCGAGCGGTTTCCCCTCCCAGACTGGGTGTGGGATCAATACGCTACAGATC
AACGAATCAACGACAACGGCATCCGTATTGACCTCGATCTCGCAGCTCACGCCATCACCGTCGACGACGTCTACCGCGAA
CATTGCGTCGACGAAGCCCAAGAAATCACCGGACTCGAAAACCCTGGCTCTCCAACGCAGCTACAAAACTGGTTGAACGT
CAACGGATGCCCTATCGAATCCATGGCTAAAGAGCACGTCCAAGCCGCGCTAAAAACAGCCACAGGATCCACACGCCGTG
TCCTCGAGCTACGCCAAGACATGTCCAGAAGCTCCGTGAAAAAGTACCAAGCCATGCAACAATGTGCGATACCAGCCACT
AGCCGAGCCCATGGGCTTCTCCAGTTTTACGGTGCGGGACGAACGGGGAGGTGGGCTGGCAGGCTTGTCCAAGTCCAAAA
CCTTCCCAGAAATTACATCCAAGATTTAGCTGGGGCCCGTGAGCTCATACGTGGAGAGCACCACAACCTCCTTGAGCTTT
TATTCGACTCGGTTCCAGATACCCTCAGCCAGCTGATTCGCACTGCGTTCATCCCCGCCGAGGGGAAAAAGTTCATTGTC
GCCGACTACTCGGCCATCGAAGCCCGCGTGTTGGCATGGCTAGCAGGCCAAGATACCACTATCCAAGCTTTCGTCGATGG
CAAAGACCTCTACTGTGCTACCGCTGCCCAAATGTTCGGTGTACCCGTCGAAAAGAATGGCCAAAACGCGGACTTGCGCC
AAAAAGGAAAAATCGCGGTCCTCGCCTGCGGATACCAAGGCGGCGTAGGCGCCATTAAAACCATGGGTGGTGAACAATTG
GGTTTCACCGAAGACGAAATGCGCACCATCGTCGACAAATGGCGATCCGCTAACCGCAAAATCGTTGCCTACTGGTATGC
CATCGACGAAGCCGCAAAGCATACCATCACAACGGGGGAACCCTCTACCGTTCGTAGCATCACTATGCGAATCGACGGAG
GAATGCTCCTTATCACCCTCCCATCTGGAAGATCCTTGGTGTACCCCAAAGCTGGCATCGGAATAAACAGGTTCGGTAAT
GACACGATTACCTTCCACGGCGTTGGAATCAATCGAAAATTCGTCAAACAAGAAACCTACGGTGGCAAGCTCGTTGAGAA
CATCACCCAAGCGGTCGCCCGAGATCTACTGGCTCACGCCCTCACAACCTTAGAAAAAGCGGGACACGCCATCGTCATGC
ACATCCACGACGAAGCCGTCATCGAAGCCGATGCCACGACACCAGTTGATGTGGTGTGTCGGCTGATGGAGCAAGCCCCC
GAGTGGGCTTCTGGGATCCCGTTGACAGCGGATGGCTATGAATGCCCTTTCTACCAAAAAGACTGA

Protein sequence :
MRTLSIDIETFSSANIAKGGAYKYAAADDFEILLFAYSVDDSPVTVVSIATGETVPADIISALTDPSVTKYAFNAQFERV
CLSRWLQQQSLLPKEEFIDPGGWRCTMVWCASIGLPMSLDQAAKVLSLKAQKISEGKSLIQYFCLPTKPREVAAPVLFDA
SGMTHRNHPQTAPERWVDFIEYNRRDVETEQEMRTKLERFPLPDWVWDQYATDQRINDNGIRIDLDLAAHAITVDDVYRE
HCVDEAQEITGLENPGSPTQLQNWLNVNGCPIESMAKEHVQAALKTATGSTRRVLELRQDMSRSSVKKYQAMQQCAIPAT
SRAHGLLQFYGAGRTGRWAGRLVQVQNLPRNYIQDLAGARELIRGEHHNLLELLFDSVPDTLSQLIRTAFIPAEGKKFIV
ADYSAIEARVLAWLAGQDTTIQAFVDGKDLYCATAAQMFGVPVEKNGQNADLRQKGKIAVLACGYQGGVGAIKTMGGEQL
GFTEDEMRTIVDKWRSANRKIVAYWYAIDEAAKHTITTGEPSTVRSITMRIDGGMLLITLPSGRSLVYPKAGIGINRFGN
DTITFHGVGINRKFVKQETYGGKLVENITQAVARDLLAHALTTLEKAGHAIVMHIHDEAVIEADATTPVDVVCRLMEQAP
EWASGIPLTADGYECPFYQKD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SEQ_2073 YP_002747288.1 phage DNA polymerase Not tested ¥ÕSeq4 Protein 2e-137 49
polA YP_494120.1 phage related DNA polymerase family A Not tested ¥ÕSa2 Protein 3e-126 45
MW1425 NP_646242.1 DNA polymerase Not tested ¥ÕSa2 Protein 4e-127 45