Gene Information

Name : TOPB45_0079 (TOPB45_0079)
Accession : YP_004627123.1
Strain : Thermodesulfobacterium geofontis OPB45
Genome accession: NC_015682
Putative virulence/resistance : Unknown
Product : GMP synthase (glutamine-hydrolyzing)
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 74539 - 76086 bp
Length : 1548 bp
Strand : +
Note : PFAM: GMP synthase, C-terminal; Glutamine amidotransferase class-I, C-terminal; tRNA methyl transferase-like; TIGRFAM: GMP synthase, C-terminal; GMP synthase, N-terminal; HAMAP: GMP synthase [glutamine-hydrolyzing]; KEGG: tye:THEYE_A0205 GMP synthase

DNA sequence :
ATGCATCCCCAAAATAAGGTTTTAGTTCTTGATTTTGGATCTCAAACTACCCAGCTTATTGCTCGCAGAATAAGAGAACT
TGGAGTTTATAGTGAAATTAAACCCTGTTTTATTAGCTTAGAGGAAATTAAAAGCTTTTCCCCCTCTGGTATAGTTTTTT
CTGGTGGACCAAGTAGTGTATATGATAAAAATGCACCTCTTATTGATAAAGAAATTTTTAGTCTTGGAATACCAATTTTA
GGAATATGTTATGGTGCTCAATTAATTACCTATATTTTAGGAGGGGTTGTTGAAAAAAGTGATAAAAGAGAATTTGGACC
AGCTTATATAGAAATCTTAAAAACAAATAAGCTTTTTAAGGGGCTTAAAAAAAACAAAAAATATAAAGTATGGATGAGTC
ATAGTGATAGAATTGAAAAATTGCCAGAAGGTTTTTATGCTTTAGCAAAAACTGAAAATTCTCCCTTTGCAGCAATAGCT
CATGAAACCAAAGCTTTATATGGAGTTCAGTTTCACCCAGAGGTAATACATACTGAAATAGGTAAAAAAATTTTACATAA
TTTCCTTTTTGAAATATGCAAATGTAAAGCTGATTGGAATATGCCCTCTTTTATTGAAGAAACCATAAAATATATTCGTA
ACCTTGTTAAAGATGAGGAAAAAGTTATATGTGCCCTTTCAGGAGGTATTGATTCTACTGTTACAGCTATACTTGTACAT
AAAGCTATAGATGATAGACTTATCCCAATTTTTGTAAATAATGGACTTTTAAGAAAAAATGAACCCGAAGAAGTTTTAGA
TTTAATGAGAAGTCTTGGACTAAAGGTTCATTATGTGGATGCAAGTTCTATATTTTTATCTCGTTTAAAAGGGATTAAAG
ACCCAGAAAAAAAGAGAAAAATTATTGGTGAAACCTTTATTGAAATTTTTGAAAGGGAAGCCCAAAAATTTGAAAATGTT
AGATATCTTGCTCAGGGAACTCTTTATCCTGATGTAATAGAAAGTACATCTTTTAGAGGACCCTCTGCAACAATTAAAAC
CCATCATAATGTAGGTGCTCTTCCAGAAAAAATGAATTTAAAACTAATAGAACCTTTAAGAGAGCTTTTTAAAGATGAAG
TAAGAAAAATTGCTGAGCTTTTAGGATTACCCAAACATATAGTTTGGAGACAGCCCTTCCCTGGTCCAGGATTAGCTGTA
AGGATAATTGGAGAAATTGATGAAGAAAAACTTAATATTTTAAGAGAAGCAGATGCAATAGTAACAGAAGAAATGCTTAA
ATCAGGATGGTATTATAAGGTGTGGCAAAGTTTTGCTGTTCTTCTCCCTATAAAAACTGTTGGTGTTATGGGAGATTTAA
GAACATATGAATATGTAATAGCTATAAGATGTGTGGAAAGTCAAGATGCTATGACTGCAGATTGGGTTAAACTTCCCTAT
GAAATTTTAGAAAAGCTCTCAAATAGAATAATAAATGAGGTAAAAGGTGTAAATAGAGTTGTATATGATATTTCTCCAAA
ACCACCAGCTACTATTGAATGGGAATAA

Protein sequence :
MHPQNKVLVLDFGSQTTQLIARRIRELGVYSEIKPCFISLEEIKSFSPSGIVFSGGPSSVYDKNAPLIDKEIFSLGIPIL
GICYGAQLITYILGGVVEKSDKREFGPAYIEILKTNKLFKGLKKNKKYKVWMSHSDRIEKLPEGFYALAKTENSPFAAIA
HETKALYGVQFHPEVIHTEIGKKILHNFLFEICKCKADWNMPSFIEETIKYIRNLVKDEEKVICALSGGIDSTVTAILVH
KAIDDRLIPIFVNNGLLRKNEPEEVLDLMRSLGLKVHYVDASSIFLSRLKGIKDPEKKRKIIGETFIEIFEREAQKFENV
RYLAQGTLYPDVIESTSFRGPSATIKTHHNVGALPEKMNLKLIEPLRELFKDEVRKIAELLGLPKHIVWRQPFPGPGLAV
RIIGEIDEEKLNILREADAIVTEEMLKSGWYYKVWQSFAVLLPIKTVGVMGDLRTYEYVIAIRCVESQDAMTADWVKLPY
EILEKLSNRIINEVKGVNRVVYDISPKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-131 53
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-131 53
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-131 53
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-119 49