Gene Information

Name : TOPB45_0063 (TOPB45_0063)
Accession : YP_004627107.1
Strain : Thermodesulfobacterium geofontis OPB45
Genome accession: NC_015682
Putative virulence/resistance : Virulence
Product : ATPase, FliI/YscN family
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : -
Position : 61503 - 62819 bp
Length : 1317 bp
Strand : +
Note : TIGRFAM: ATPase, type III secretion system, FliI/YscN; PFAM: ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain; ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal; KEGG: cob:COB47_1951 ATPase, FliI/YscN family; SMART: ATPase, A

DNA sequence :
ATGAAGGTTAAAAATTTAGAAGAATACAAAAAAGAGATTTCGCAAATAATTCCTTTTGAAATTTATGGATACGTTACTAA
ACTCATTGGCTTAACCATTGAAAGTACTGGACCGTTTTTAAAAGTAGGGGATCTTTGTAAAATTGAGGGGCAAAGTACAA
ATTTAATTGCAGAAGTTATAGGTTTTAAAGATAATAAGCTTTTGCTAACAGCTTTGGGTGATATAAAGGGAATTGAAGTT
GGGGCAAAGGTCTTTCCTATAGGTTCTTCTTATGCGCCTGTAGGAGAAGATTTTCTTGGAAGAATAGTAAATGCTTTAGG
AGAACCTTTAGATAATAAGAGAAAGCCTAAAATTTCGGATTTTTATCCCCTTTATGGAGAACCTTTAAAACCTTTAGAAA
GAGCTCCGATAAAAGAAATTTTAGATGTAGGGATAAAAGCTATTAATGCACTTTTAACTATAGGAAGAGGACAAAGGGTA
GCTATAATGGCAGGTTCTGGAGTAGGAAAAAGTACCCTTCTTGGAATGATAGCAAGATATACCAGTGCAGATGTAAATGT
TATTGCTTTAATAGGAGAAAGAGGAAGAGAAGTGAGAGAATTTATAGAGAGAGATTTAAAAGAAGATGGGTTAAAAAAAT
CAGTTGTTGTAGTAGCAACCTCTGACGAAGCCCCATCAATAAGAATAAGAGCTGCCTATTATGCTACTTCTCTTGCTGAA
TATTTTAGAGATAAAGGATATAAAGTGCTTCTTCTTATGGATTCTTTAACCAGGTTTTGTATGGCAGGAAGAGAAATAGG
TCTTGCTTCTGGAGAACCTCCTACAGCTCGTGGATATACTCCCTCTGTATTTGCAATACTTCCTAAGCTTTTAGAAAGAG
CCGGTCCAAAAATCGGTGCAGGTGATATTACTGGAATATATAATGTTTTGGTAGAAGGGGATGATTTTAATGACCCCATA
GCTGATTCAGTGAGAAGTATAGTAGATGGACATATTGTACTTTCAAGAGACCTGGCTCATGAGGGACACTATCCTCCTAT
TGATATTCTTGCAAGTATAAGCAGAGTAATGAGAGACATCGTCCCGAAGGAACATTTAGATTTAGCTTATCAAACTATAG
CAATTTTAGCTACTTATAAAAAAGCCGAAGATCTTATTAATATAGGAGCTTATGTTAAAGGTTCCAATCCAGATATAGAC
AGAGCTATTTCTTTAATAGGTGATCTAAAAAATTTTCTAAAACAACCAGTAGAAGAAAAATATTCTTTGGAAGATTCAGT
TAACTTATTAAAAGAAATTATTAATAAAAAATTATGA

Protein sequence :
MKVKNLEEYKKEISQIIPFEIYGYVTKLIGLTIESTGPFLKVGDLCKIEGQSTNLIAEVIGFKDNKLLLTALGDIKGIEV
GAKVFPIGSSYAPVGEDFLGRIVNALGEPLDNKRKPKISDFYPLYGEPLKPLERAPIKEILDVGIKAINALLTIGRGQRV
AIMAGSGVGKSTLLGMIARYTSADVNVIALIGERGREVREFIERDLKEDGLKKSVVVVATSDEAPSIRIRAAYYATSLAE
YFRDKGYKVLLLMDSLTRFCMAGREIGLASGEPPTARGYTPSVFAILPKLLERAGPKIGAGDITGIYNVLVEGDDFNDPI
ADSVRSIVDGHIVLSRDLAHEGHYPPIDILASISRVMRDIVPKEHLDLAYQTIAILATYKKAEDLINIGAYVKGSNPDID
RAISLIGDLKNFLKQPVEEKYSLEDSVNLLKEIINKKL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 1e-93 48
escN AAC38383.1 EscN Virulence LEE Protein 4e-77 48
escN NP_290268.1 hypothetical protein Virulence LEE Protein 4e-77 48
escN AAC31513.1 L0034 Virulence LEE Protein 3e-77 48
ECs4568 NP_312595.1 EscN Virulence LEE Protein 4e-77 48
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 3e-77 48
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 2e-88 47
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 9e-85 47
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 9e-85 47
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-87 47
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 9e-88 47
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-87 47
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 6e-88 47
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 8e-88 47
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 6e-88 47
unnamed AAL06369.1 EscN Virulence LEE Protein 1e-76 47
escN AAK26715.1 EscN Virulence LEE Protein 2e-77 47
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 9e-78 47
escN AAL57542.1 EscN Virulence LEE Protein 2e-77 47
escN CAC81862.1 EscN protein Virulence LEE II Protein 8e-78 47
escN YP_003236088.1 translocator EscN Virulence LEE Protein 1e-76 47
escN CAI43874.1 EscN protein Virulence LEE Protein 7e-78 47
escN YP_003223475.1 translocator EscN Virulence LEE Protein 9e-78 47
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 3e-76 47
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 3e-76 47
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 4e-76 46
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 4e-76 46
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 7e-77 46
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 4e-77 46
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 6e-77 46
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 3e-80 46
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 4e-72 44
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 2e-70 43
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 4e-74 43
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 6e-74 43
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 9e-73 43
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 1e-68 42
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 1e-68 42
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 2e-78 42
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 4e-73 42
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 4e-62 42
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 2e-71 41
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 1e-71 41
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 3e-72 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TOPB45_0063 YP_004627107.1 ATPase, FliI/YscN family VFG2499 Protein 9e-95 51
TOPB45_0063 YP_004627107.1 ATPase, FliI/YscN family VFG1254 Protein 1e-97 50
TOPB45_0063 YP_004627107.1 ATPase, FliI/YscN family VFG0390 Protein 1e-94 50
TOPB45_0063 YP_004627107.1 ATPase, FliI/YscN family VFG2331 Protein 2e-92 49
TOPB45_0063 YP_004627107.1 ATPase, FliI/YscN family VFG0192 Protein 5e-97 49
TOPB45_0063 YP_004627107.1 ATPase, FliI/YscN family VFG2144 Protein 3e-98 48
TOPB45_0063 YP_004627107.1 ATPase, FliI/YscN family VFG0048 Protein 8e-94 48
TOPB45_0063 YP_004627107.1 ATPase, FliI/YscN family VFG0730 Protein 2e-77 48
TOPB45_0063 YP_004627107.1 ATPase, FliI/YscN family VFG0812 Protein 2e-77 48
TOPB45_0063 YP_004627107.1 ATPase, FliI/YscN family VFG0515 Protein 2e-77 46
TOPB45_0063 YP_004627107.1 ATPase, FliI/YscN family VFG1008 Protein 3e-63 41