Gene Information

Name : TOPB45_1576 (TOPB45_1576)
Accession : YP_004628582.1
Strain : Thermodesulfobacterium geofontis OPB45
Genome accession: NC_015682
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 1581918 - 1583411 bp
Length : 1494 bp
Strand : -
Note : PFAM: Aminoacyl-tRNA synthetase, class II (D/K/N); Nucleic acid binding, OB-fold, tRNA/helicase-type; TIGRFAM: Lysyl-tRNA synthetase, class II; HAMAP: Lysyl-tRNA synthetase; KEGG: dvl:Dvul_0888 lysyl-tRNA synthetase

DNA sequence :
ATGACAGAGGAACACCAAATTATAAAGGTAAGATATGAGAAGCTTTCTGCTATAGAAAAAATGGGAATAAAAAGTTATCC
TAATGATTTTCGTCCTCAAGATAAAGCTAAATATTTAAAAGAAATTTATAAAGATATGCCTCCAGAGGAACTTGAAAAAA
GAGAAGCTGAATTTTCCTTAGCTGGTAGGGTTATGAGTAAAAGAGAAATGGGGAAAATTATTTTTTCTCATATTCAAGAT
GAGACAGACAAAATCCAGATTTTGATAGCTAAATCTGAGTTACCAGAGGAAGATTTTAATTTCTTCAAAAAATTTATAGA
TATAGGAGATATTATAGGAGTTAAAGGCAAACTTATTAAAACCAAAACAGGTGAAATAACCATCTTGGTTAAATTTTTAA
AACTTCTTACCAAAGCCTTAAGACCCCTTCCTGAAAAATATCATGGATTAAGAGATACAGAACTAAGATATAGAATGAGA
TATTTAGACCTAATAATGAATCAAAGGGTAAGAGAAATTTTTAGGATGAGAACCCAAATTATCCAATATATAAGAGATTA
TTTTATTTCTGAAGGTTTTTTAGAAGTAGAAACTCCTATGATGCATCCTATTGTAGGAGGTGCAACTGCAAAACCTTTTG
TGACTTATCATAATGCCTTAGATATGAATCTTTATTTGAGAATTGCTCCTGAACTTTATTTAAAAAGACTCCTTGTAGGG
GGATTTGAAAGGGTTTTTGAATTAAATAGAAATTTCAGAAATGAAGGGGTTTCAAGCAAACACAATCCAGAATTTACTAT
GCTTGAATTTTATGAAGCCTACGCTACCTATGAAGATCTTATGAAAAGAACAGAAGAACTGTTTTACGGTCTTGCATTGG
AAATAAAAGGAACTCCAGTAATAACCTATCAGGGTAATGAAATTGATCTTACTCCTCCTTGGAAAAGAATAGAATTTTTA
AAAGCTTTAACTGAGTTAGGAGGAATACCTGAAGAAATTTTAAATGACAGAGAAAAACTTTTCAATTTTGCTAAAGAAAA
GGGGATCGAGCTTAATTTAAAAGATCCCCGTATTGGTAAATGGTGGACTAAACTTTTTGAAGAACTTGTTGAACCTAAGC
TCATTCAACCTACCTTTGTAATAAAATATCCTGTAGAAGTTTCTCCACTTGCAAGAAGAAATGACGAAGATCCAAGGTTT
GCAGATAGATTTGAATTTTATATGGGTGGGAAGGAAATTGCTAATGCCTTTTCCGAATTAAATGATCCAAGAGATCAGAG
AAAACGTTTTGAAGAACAACTTAAATTAAGAGAAATAGATGAAGAAATACCTCCGGAAATAGATGAAGATTTCTTAAGGG
CTCTAGAATATGGTATGCCTCCTTGTGCAGGAGAAGGAATAGGAATTGATAGGGTAGTTATGATTTTTACAGATAGTCCA
TCTATTAGAGAAATTATCTTGTTTCCTCATTTAAGAAAAAAAGAAGATTTATAA

Protein sequence :
MTEEHQIIKVRYEKLSAIEKMGIKSYPNDFRPQDKAKYLKEIYKDMPPEELEKREAEFSLAGRVMSKREMGKIIFSHIQD
ETDKIQILIAKSELPEEDFNFFKKFIDIGDIIGVKGKLIKTKTGEITILVKFLKLLTKALRPLPEKYHGLRDTELRYRMR
YLDLIMNQRVREIFRMRTQIIQYIRDYFISEGFLEVETPMMHPIVGGATAKPFVTYHNALDMNLYLRIAPELYLKRLLVG
GFERVFELNRNFRNEGVSSKHNPEFTMLEFYEAYATYEDLMKRTEELFYGLALEIKGTPVITYQGNEIDLTPPWKRIEFL
KALTELGGIPEEILNDREKLFNFAKEKGIELNLKDPRIGKWWTKLFEELVEPKLIQPTFVIKYPVEVSPLARRNDEDPRF
ADRFEFYMGGKEIANAFSELNDPRDQRKRFEEQLKLREIDEEIPPEIDEDFLRALEYGMPPCAGEGIGIDRVVMIFTDSP
SIREIILFPHLRKKEDL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 5e-100 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TOPB45_1576 YP_004628582.1 lysyl-tRNA synthetase VFG1668 Protein 3e-100 48