Gene Information

Name : TOPB45_1080 (TOPB45_1080)
Accession : YP_004628099.1
Strain : Thermodesulfobacterium geofontis OPB45
Genome accession: NC_015682
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 1073529 - 1074266 bp
Length : 738 bp
Strand : +
Note : PFAM: Acylneuraminate cytidylyltransferase; TIGRFAM: 3-deoxy-D-manno-octulosonate cytidylyltransferase; HAMAP: 3-deoxy-D-manno-octulosonate cytidylyltransferase; KEGG: spl:Spea_1985 3-deoxy-manno-octulosonate cytidylyltransferase

DNA sequence :
ATGAGAAAGGTAATCATTATTCCTGCAAGATATGGATCTACAAGATTTCCTGGTAAACCTTTAGCTTTGCTTTGGGGTAA
AACTATTATTCGTCATGTTTATGAAAGAGCTTTAGCTTCAGAAATAGAAGAAATATATGTAGCAACTGATGATGAAAGAA
TTTTTAATGAAGTAATAAGTTTTGGAGGAAAAGCAATTTTAACAAGTAAAGAACATACCTGCGGTACCGAAAGAGTTGCA
GAAGCAGTTAATATTTTAGGACTTGATGAAGAAGACCTAATAATAAACTTGCAAGCTGATCAACCCCTTTTCCCCTCTGA
ATATTTTTCCTTGCTCATAAAACCCTTATTATTTTCTTCTGATATTCATATGAGCACTCTTGCAACACCTATAAAAAATT
TAAAAGATCTTGAAAATCCTAATAGAGTAAAAGTAGTTTTAGATAAAGAAGGTAGGGCACTTTATTTTTCTAGATCTTCT
ATTCCCTATTTTGTTCCTTCTGGTAAAGAACCACTCTATTTAAAACATATAGGAGTTTATGCTTATACAAAAGGTTTTTT
AGATAAATTTATAAGTCTTCCACCAGGAGATTTAGAAGCTTCTGAAAAACTTGAGCAATTAAGGGCTTTAGAATATGGTT
ATAAAATAGCTGTAACAGTAGTACCAAAAGAGGTTCCAGAAGTTGATACCCCTGAAGATTTGGAATATATAAAAACTTTA
AAAGAGGAAGAGCTATGA

Protein sequence :
MRKVIIIPARYGSTRFPGKPLALLWGKTIIRHVYERALASEIEEIYVATDDERIFNEVISFGGKAILTSKEHTCGTERVA
EAVNILGLDEEDLIINLQADQPLFPSEYFSLLIKPLLFSSDIHMSTLATPIKNLKDLENPNRVKVVLDKEGRALYFSRSS
IPYFVPSGKEPLYLKHIGVYAYTKGFLDKFISLPPGDLEASEKLEQLRALEYGYKIAVTVVPKEVPEVDTPEDLEYIKTL
KEEEL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 3e-42 43
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 4e-42 43
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 9e-42 43