Gene Information

Name : TOPB45_1069 (TOPB45_1069)
Accession : YP_004628088.1
Strain : Thermodesulfobacterium geofontis OPB45
Genome accession: NC_015682
Putative virulence/resistance : Virulence
Product : phosphonate-transporting ATPase
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG1136
EC number : 3.6.3.28
Position : 1062148 - 1062825 bp
Length : 678 bp
Strand : -
Note : PFAM: ABC transporter-like; KEGG: cbf:CLI_0142 macrolide efflux ABC transporter, ATP-binding protein; SMART: ATPase, AAA+ type, core

DNA sequence : 
GTGGTAGAAAAACTTGTAATTCTTAAAAATATCACCAAAACCTACAAAACCGGCAAAATAGCTTATCAAGTTTTAAAAGG
AATTAATTTAGAAGTGGAAGAAAAAGAATTTTTAGCTATAATGGGAGCTTCTGGAAGTGGAAAAACCACCCTTTTGAATA
TTATAGGTCTTCTTGATAAACCTGACTCAGGTATTTATATATTTGACGGGCAAGAAGTAAGCAAATTAAATAAAAATGAT
CTTGCTTATATAAGAAATAGAAAGATAGGTTTTGTATTTCAAGCTTTCCATTTAGTTCCTTGGGCTACTGCTCTTGAAAA
TGTTTTAATGCCTCTTTTATATAGAGGGGTTTTTAAAAAAGAAGATGAAGAAAGAGCTTTACAACTTTTAACTCGTTTAG
GACTTGAAAAAAGAATGAATGCAAAACCAAGTGAACTTTCAGGTGGAGAACAACAAAGGGTAGCTATTGCAAGAGCTCTT
ATTACCCATCCTAAACTTCTTTTAGCTGATGAACCTACAGGAAATCTTGATAGTAAAAGTTCTCAAGAAGTAATGAAAAT
TTTTAAAGAACTCAATGAAGAAGGACTTACCATTATTATGGTTACCCATGATCCTGAAATTGCTAAATTTGCTCAAAGAA
TTAAAATAATAAAAGATGGTGTGTTTGTAGAAAAATGA

Protein sequence : 
MVEKLVILKNITKTYKTGKIAYQVLKGINLEVEEKEFLAIMGASGSGKTTLLNIIGLLDKPDSGIYIFDGQEVSKLNKND
LAYIRNRKIGFVFQAFHLVPWATALENVLMPLLYRGVFKKEDEERALQLLTRLGLEKRMNAKPSELSGGEQQRVAIARAL
ITHPKLLLADEPTGNLDSKSSQEVMKIFKELNEEGLTIIMVTHDPEIAKFAQRIKIIKDGVFVEK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
Spaf_1862 YP_006310627.1 amino acid ABC transporter ATP-binding protein Not tested FWisland_2 Protein 6e-37 46
Cp1002_1464 YP_005681730.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 6e-30 42
cur_1502 YP_001800896.1 cell division ATP-binding protein FtsE Not tested Not named Protein 2e-26 42
unnamed AAP55232.1 unknown Not tested SaPIbov2 Protein 3e-30 41
SARLGA251_00480 YP_005754062.1 ABC-type transport system ATPase Not tested Type-XI SCCmec Protein 3e-30 41
CpC231_1466 YP_005683828.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 9e-31 41
cpfrc_01473 YP_003783873.1 hypothetical protein Not tested PiCp 5 Protein 9e-31 41
CpI19_1473 YP_005685914.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 9e-31 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TOPB45_1069 YP_004628088.1 phosphonate-transporting ATPase NC_012469.1.7686878. Protein 4e-53 54
TOPB45_1069 YP_004628088.1 phosphonate-transporting ATPase NC_008702.1.4606598. Protein 2e-45 48
TOPB45_1069 YP_004628088.1 phosphonate-transporting ATPase CP001581.1.gene798.p Protein 7e-40 47
TOPB45_1069 YP_004628088.1 phosphonate-transporting ATPase CP001581.1.gene598.p Protein 6e-37 46
TOPB45_1069 YP_004628088.1 phosphonate-transporting ATPase NC_012469.1.7686946. Protein 2e-28 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TOPB45_1069 YP_004628088.1 phosphonate-transporting ATPase VFG0869 Protein 1e-24 43