Gene Information

Name : TOPB45_1008 (TOPB45_1008)
Accession : YP_004628030.1
Strain : Thermodesulfobacterium geofontis OPB45
Genome accession: NC_015682
Putative virulence/resistance : Unknown
Product : ATP-dependent chaperone ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 994432 - 997050 bp
Length : 2619 bp
Strand : -
Note : TIGRFAM: Chaperonin ClpB; PFAM: ATPase associated with various cellular activities, AAA-2; ATPase, AAA-type, core; Clp, N-terminal; Clp ATPase, C-terminal; KEGG: pth:PTH_2122 ATPase with chaperone activity, ATP-binding subunit; SMART: ATPase, AAA+ type, c

DNA sequence :
ATGAAACTTGATAAGTTTACTTTTAAAGCACAAGAAGCCTTACAGAGTGCTCAGCGTTTAGCTGAAACCTATAACCATCC
TCAGATAGAACCAGAACATCTTTTAAAAGCATTAGTTGATCAAGAAGGTGGAATAGTACCTACAATCCTTGATAGATTAG
GAGTAAATTCAAAAATTATTTCTTCAGATTTAGACGAAATTTTAGAAAAATTTCCTAAACTTACTTATGGAACTTATCAA
TTATATATTTCTTTAAGTTTAAAACAAATACTCGATAAAGCCGAAAGTTTAGCTAAAGAGATGAGAGATGAATATATTTC
TACTGAGCATTTATTTTTAAGTATCATTGATAGCCCAACCAGAGCTGGAGAAATTTTAAGAAAAAGAGGTATTACTTTTA
GCAATGCTAAAGATGTAATTACAAAAATAAGAAAAGGACAAAGGATTACAGATCAAAATCCAGAAGAAAAATATCAAGCT
TTAGAAAAATTTGGAAGAGATCTTACAGCGCTTGCTAAAGCTGGAAAACTTGATCCTGTTATAGGAAGAGATGAGGAAAT
AAGAAGGGTTATGCATATTCTTTCCAGAAGAACTAAAAATAATCCTGTTCTTGTTGGAGAACCAGGTGTTGGTAAAACTG
CTATTGTAGAAGGTCTTGCTCAAAGAATCGTTGCTGGAGATGTACCTGAAGTTTTGAAAGATAAAAGAATTATTCAATTA
GATTTAGGAGCCTTAATTGCAGGAACAAAATTTAGGGGAGAATTTGAAGAAAGACTTAAAGCTGTTTTACGTGAAATTCA
AGCCAGTGAAGGAGAAATTATTTTATTTATAGACGAAATTCATACTATTGTAGGTGCTGGAGCTGCTGAAGGAGCTATAG
ATGCAGCAAATATGCTTAAACCTGCCCTTGCAAGAGGGGAATTAAGATGTATAGGTGCAACAACCATTGATGAATATCGT
AAATATATAGAGAAAGATCCTGCATTAGAAAGAAGATTTCAACCTGTTTATGTAGATGAACCAACCCCAGAAGAAGCTAT
TGCAATTTTAAGAGGATTAAAAGAAAAATATGAAGTTCACCATGGAGTTAGAATTACTGATAATGCTATTATTGCTGCTG
TTATGCTTTCTCATAGATATATTACTGATAGATATCTTCCTGATAAAGCTATAGATCTAATAGATGAAGCTGCTGCAAAA
CTTCGTATAGAAATAGATTCTATGCCAACTGAAATAGATGAAATAGAAAGAAAAATTAAACAACTTGAAATTGAAAAAGT
TGCTTTAGAAAAAGAAACTGATCCTAAAGCAAAAGAAAGACTCAATAAATTACTTGAGCAATTAAATGAACTTAGAAAAG
AGGCTGAAAAATTAAAAGCTCAATGGTTAAAAGAAAAAGAGGTTATTCAAAAAATTAGAAAATTAAAAGAAAAAATTGAC
CAACTTAAAATCGAAGCTCAACAAGCTGAAAGACAAGGTGATCTAAATAGAGTTGCTGAAATTATATATGGCATGATTCC
TCAACTTCAAAAGGAATTAGAAGAAGAAAATAAAAAATTAGAAGAACTTCAAAAGGAACATAAATTCTTAAAAGAGGAAG
TAGATGCTGAAGATATAGCTCAAATTGTATCTAAATGGACAGGAATACCTGTGCACAGACTTCTTGAAAGTGAAAGGGAA
AAACTTTTAAGAATAGAAGAAAGATTGAAAGAAAGGGTGGTCGGGCAGGATCATGCTATTTCTGCAATAGCAAATGCTTT
AAGAAGAGCAAGAGCAGGACTAAAAGATCCAAGAAGACCTATTGGTTCTTTTCTCTTTATTGGTCCTACAGGAGTAGGAA
AAACAGAACTTGCGAAAGCACTTGCTGAATTTATGTTTGATACTGAAGATGCAATGATAAGAATTGATATGACAGAATAT
ATGGAAAAACATTCTGTTTCAAGATTAATTGGTGCACCTCCTGGATACGTTGGATATGAAGAAGGAGGACAACTTACTGA
AGCAGTAAGAAGAAGACCTTATTCTGTTATTTTGTTTGATGAAATCGAAAAGGCTCATCCCGATGTTTTTAACATTCTGC
TTCAGATTCTTGACGATGGGAGATTAACTGATGGTAAAGGAAGAACCGTTGATTTTAAAAATACAATTATAATTATGACT
TCAAATGTAGGTAGTTTCTATTTCCAAGATTTGTCTCTTTCTCGTAAAGAAGTAGAAAATAGAGTATTTGAACTTTTAAA
ATCCACTTTCAGACCTGAATTTTTAAACCGTATAGATGAAATTATAGTCTTTAATAATTTAACCAGAGAGGACATAATTA
AAATTGTAGATATCCAAATTAGGTATCTCAATGAAAGACTTTCTGAAAAAGGAATGTTCTTAGAACTAACTGATAAAGCT
AAAGAACTTCTTGCAACTTATGGATATGACCCAGTCTTTGGAGCAAGACCGCTTAAAAGAACTATACAAAAATATATTGA
AAATGCTTTAGCTTTGAAAATTTTAGAAGGTGTTTTTTCTGAAGGAGATAAAATAATAGTTGATGTAAACGAAGCAGGAG
AATTTGAATTTAGAAAAGCTGAAGAAGTAGAAGAATTAAGGAAAGTTGCACTTCATTAA

Protein sequence :
MKLDKFTFKAQEALQSAQRLAETYNHPQIEPEHLLKALVDQEGGIVPTILDRLGVNSKIISSDLDEILEKFPKLTYGTYQ
LYISLSLKQILDKAESLAKEMRDEYISTEHLFLSIIDSPTRAGEILRKRGITFSNAKDVITKIRKGQRITDQNPEEKYQA
LEKFGRDLTALAKAGKLDPVIGRDEEIRRVMHILSRRTKNNPVLVGEPGVGKTAIVEGLAQRIVAGDVPEVLKDKRIIQL
DLGALIAGTKFRGEFEERLKAVLREIQASEGEIILFIDEIHTIVGAGAAEGAIDAANMLKPALARGELRCIGATTIDEYR
KYIEKDPALERRFQPVYVDEPTPEEAIAILRGLKEKYEVHHGVRITDNAIIAAVMLSHRYITDRYLPDKAIDLIDEAAAK
LRIEIDSMPTEIDEIERKIKQLEIEKVALEKETDPKAKERLNKLLEQLNELRKEAEKLKAQWLKEKEVIQKIRKLKEKID
QLKIEAQQAERQGDLNRVAEIIYGMIPQLQKELEEENKKLEELQKEHKFLKEEVDAEDIAQIVSKWTGIPVHRLLESERE
KLLRIEERLKERVVGQDHAISAIANALRRARAGLKDPRRPIGSFLFIGPTGVGKTELAKALAEFMFDTEDAMIRIDMTEY
MEKHSVSRLIGAPPGYVGYEEGGQLTEAVRRRPYSVILFDEIEKAHPDVFNILLQILDDGRLTDGKGRTVDFKNTIIIMT
SNVGSFYFQDLSLSRKEVENRVFELLKSTFRPEFLNRIDEIIVFNNLTREDIIKIVDIQIRYLNERLSEKGMFLELTDKA
KELLATYGYDPVFGARPLKRTIQKYIENALALKILEGVFSEGDKIIVDVNEAGEFEFRKAEEVEELRKVALH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 1e-96 43