Gene Information

Name : TOPB45_0986 (TOPB45_0986)
Accession : YP_004628009.1
Strain : Thermodesulfobacterium geofontis OPB45
Genome accession: NC_015682
Putative virulence/resistance : Unknown
Product : Homoserine dehydrogenase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0460
EC number : 1.1.1.3
Position : 972691 - 973986 bp
Length : 1296 bp
Strand : +
Note : KEGG: tye:THEYE_A1986 homoserine dehydrogenase (HDH): ThrA, MetL; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/homoserine dehydrogenase, NAD-binding; Amino acid-binding ACT

DNA sequence :
ATGAAGGAAGTAAATATAGCCTTACTTGGATTCGGAACAGTTGGAACGGGAGTCTATGAATTATTAATTAAAAATTCCGA
TCTTATAAAAGAAAAAATAGGAATAAAGCCAATAATAAAAAAAATTTTGGTGAAGGATTTGAAAAAGAAAAGAGAAATAG
AAGTAGATAAAAATCTTTTAACCACTAATGTAGAAGAAATTTTAAAAGATCCTGAAATTTCCATTGTTTGTGAATTGATG
GGTGGTATAGAGCCAGCTAAAGAATATGTTTTAAAAGCTTTAAAAGAAGGAAAGGAAGTAGTTACAGCAAATAAAGCGAT
TTTAGCTCAACATGGAGATGAAATTTGGGAAGAAGCAAGAAAAAGAAAAAGATTTTTGGGTTTTGAAGCTTCAGTTGGTG
GTGGGATACCTATAATAAAGACTTTAAAAGAGGCTTTAATTGGGAATAACATAAAGTCTATAATAGGCATTATAAATGGT
ACTACTAATTATATTTTAACCAAAATGCTTGAAAATAATCTTAGTTTTAAAGATGCATTAAAAGCAGCTCAAGCAAAAGG
ATATGCAGAGGCTGACCCGACTCTGGATATAAAAGGGATTGATTCAGCTCACAAAATTTCAATTTTAGCTTCTCTTGCAT
TTGGATTTTACATACCAGTTTCAAAAGTTTATATAGAAGGAATAGATCAAATAGATTTAATGGATTTAAAATTTGCTAAA
GATTTTGGATACGTAGTTAAATTATTAGCTTTTGCTTTAAAAAGAAAAGGAAAAATTGAAGTAAGGGTTCACCCTACTCT
TATTCCTGAGAATCATGTATTGACTTCAGTCCGTTTGAATTACAATGCCCTTTACATTACAGGGGATTTTGTAGGTGATA
TTTTACTTTATGGATTAGGAGCAGGCAAAGAGCCTACTGCAAGTGCAGTGGTAAGCGATATAATTGATGCAATAGAGTAT
TCTTATTTTGGGAAAAAACCCTTTATAAAATATCCATTGACAAAAAATAATAATTTTTTTAATATAAGACCTATAGAAGA
AGTAGAGTTTAAATATTATTTTAGATTTTCAGCCATAGATAAACCTGGTGTTTTATCTAAAATTTCTGGTATCTTGGGTA
AAAATAATATAAGCATAGCTTCAGTAGTTCAGATAGGAAGGCAAAAAAAGAAAGGTTCTGTACCTGTGGTTATGCTTACT
CATGAAACTAAAGAAAAAAATGTAATTAAAGCCTTACAAGAAATAGATAAACTTGATGTAGTTACTGCTCCTACTAAAAA
ATTTAGAATTTTGTAA

Protein sequence :
MKEVNIALLGFGTVGTGVYELLIKNSDLIKEKIGIKPIIKKILVKDLKKKREIEVDKNLLTTNVEEILKDPEISIVCELM
GGIEPAKEYVLKALKEGKEVVTANKAILAQHGDEIWEEARKRKRFLGFEASVGGGIPIIKTLKEALIGNNIKSIIGIING
TTNYILTKMLENNLSFKDALKAAQAKGYAEADPTLDIKGIDSAHKISILASLAFGFYIPVSKVYIEGIDQIDLMDLKFAK
DFGYVVKLLAFALKRKGKIEVRVHPTLIPENHVLTSVRLNYNALYITGDFVGDILLYGLGAGKEPTASAVVSDIIDAIEY
SYFGKKPFIKYPLTKNNNFFNIRPIEEVEFKYYFRFSAIDKPGVLSKISGILGKNNISIASVVQIGRQKKKGSVPVVMLT
HETKEKNVIKALQEIDKLDVVTAPTKKFRIL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00309 YP_008211635.1 Homoserine dehydrogenase Not tested AbaR26 Protein 2e-56 42
BJAB07104_00305 YP_008207770.1 Homoserine dehydrogenase Not tested AbaR25 Protein 2e-56 42