Gene Information

Name : Thein_0484 (Thein_0484)
Accession : YP_004625330.1
Strain : Thermodesulfatator indicus DSM 15286
Genome accession: NC_015681
Putative virulence/resistance : Virulence
Product : Fis family two component sigma-54 specific transcriptional regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG2204
EC number : -
Position : 509312 - 510667 bp
Length : 1356 bp
Strand : -
Note : COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterProIPR001789:IPR002078:IPR002197:IPR020441:IPR 003593; KEGG: sat:SYN_02530 two-component response regulator; PFAM: sigma-54 factor interaction dom

DNA sequence :
ATGTCTACGCCTACTATCCTTATTGTTGACGACGACAAAAGTTTACAAGAATTTTTAGAGCTTTTTCTGGCCAAGGAGGG
CTACCGAGTAGCTGTTGCTGGAGACGGCGAAGAGGCCCTTTCTTATTTATCTAAAAACCCGGCGGACTTGATATTGGCTG
ACATTCGCATGCCCCGCCTTGATGGGATTTCTTTTCTGAAAGCCTTGCGCGAAAGAGCTTTACGTATTCCGGTGATAATG
ATTACGGCTTACGCCTCTCTTGATACCGCGGTAACCGCCAAACAAGAGGGGGCTTTTGATTATGTGCCCAAGCCTTTTAA
ACTTGATCAGTTGCGCGATTTAATAAAAAAGGCGCTAGCTCAAGAAAGGGTTTCCATTGAGGCCACGGTCAGTGAAACTT
CTTTCATGGGCATAATAGGGAAAAGCCCGGCCATGAGGCGGGTTTTTGAGGTTTTGCCGCGTATTGCCAACGCGCCTTCA
AATGTGCTTATTACCGGTGAATCGGGTACTGGTAAGGAGCTTATAGCCAGGGCTATTCATCAGCTTTCACCCCGTCGTGA
TAGGCCTTTTGTGGTAGTGAACTGTGGTGGTATCCCACCAAATCTCCTGGAGAGCGAGCTTTTTGGCTATAAAGCCGGGG
CCTTTACCGGGGCCTCGCGGGACAAAGAAGGCCTTTTTCTCAAGGCCCACAAAGGCACTATCTTTCTTGACGAAATAGGC
GAACTCCCCCTTGAGATGCAGGTTAAACTCTTGAGGGTTGTTCAAGAAAAGGCCGTTATGCCTCTTGGTTCGGCTAAGGA
AATAAAAGTTGACGTGAGAATAATTTCAGCTACTAACCGAGACCTTGAAAAGGAAGTTCTGGCAGGCAATTTCAGGGAAG
ACCTCTTTTATCGCTTAAATGTAATTTCCCTCGAGTTGCCTCCGCTAAGAGAGCGCAAAGAAGATATTCCCCTTTTAGTG
GATTATTTTCTCAAAAAATATGCCGAAAAAATGGGTAAAAAGATTGAAGGTATTTCTGATTTTGCCCTTAAGGCCCTCAT
GGAATATGACTTTCCAGGAAATGTGCGTGAGCTTGAAAACATAATAGAACGTTCGGTAGCCCTTGAATCAGGTCCTCTTA
TTTTACCGGAAAGTCTTGTCCTTTCGCGGAAAAATAGAGAAAATTCAAATGGAGCCTTTGAAATAGAACTCCCTGAAGAG
GGCCTTGATTTAGAAGATCTATTGGCCCGTATAGAAGTCTCTCTTCTTAAGCAGGCTCTCGCCCGCACAGGAGGAAACAA
GACCGAAGCGGCCAAGCTTTTGGGCTTAAACTTCAGGTCTTTGCGTTATCGGTTGGCGAAATATGGTCTTTCTTGA

Protein sequence :
MSTPTILIVDDDKSLQEFLELFLAKEGYRVAVAGDGEEALSYLSKNPADLILADIRMPRLDGISFLKALRERALRIPVIM
ITAYASLDTAVTAKQEGAFDYVPKPFKLDQLRDLIKKALAQERVSIEATVSETSFMGIIGKSPAMRRVFEVLPRIANAPS
NVLITGESGTGKELIARAIHQLSPRRDRPFVVVNCGGIPPNLLESELFGYKAGAFTGASRDKEGLFLKAHKGTIFLDEIG
ELPLEMQVKLLRVVQEKAVMPLGSAKEIKVDVRIISATNRDLEKEVLAGNFREDLFYRLNVISLELPPLRERKEDIPLLV
DYFLKKYAEKMGKKIEGISDFALKALMEYDFPGNVRELENIIERSVALESGPLILPESLVLSRKNRENSNGAFEIELPEE
GLDLEDLLARIEVSLLKQALARTGGNKTEAAKLLGLNFRSLRYRLAKYGLS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00300 YP_008207765.1 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Not tested AbaR25 Protein 2e-78 41
BJAB0868_00304 YP_008211630.1 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Not tested AbaR26 Protein 2e-78 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Thein_0484 YP_004625330.1 Fis family two component sigma-54 specific transcriptional regulator BAC0089 Protein 6e-86 50
Thein_0484 YP_004625330.1 Fis family two component sigma-54 specific transcriptional regulator BAC0467 Protein 6e-87 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Thein_0484 YP_004625330.1 Fis family two component sigma-54 specific transcriptional regulator VFG1214 Protein 6e-88 48
Thein_0484 YP_004625330.1 Fis family two component sigma-54 specific transcriptional regulator VFG1249 Protein 4e-71 45
Thein_0484 YP_004625330.1 Fis family two component sigma-54 specific transcriptional regulator VFG0116 Protein 6e-62 43