Gene Information

Name : Thein_1566 (Thein_1566)
Accession : YP_004626391.1
Strain : Thermodesulfatator indicus DSM 15286
Genome accession: NC_015681
Putative virulence/resistance : Unknown
Product : GMP synthase, large subunit
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 1625479 - 1627026 bp
Length : 1548 bp
Strand : +
Note : COGs: COG0519 GMP synthase PP-ATPase domain/subunit; InterProIPR011702:IPR006220:IPR001317:IPR004739:IPR 001674:IPR017926:IPR000991; KEGG: tye:THEYE_A0205 GMP synthase; PFAM: GMP synthase domain protein; glutamine amidotransferase class-I; SPTR: GMP synth

DNA sequence :
ATGGAACAAGGAGATCGTATTTTAGTGCTGGATTTTGGCTCGCAAACTACCCAGCTCATTGCCAGGCGGGTAAGGGAGCT
TCACGTCTACAGTGAAATTAAACCATGTGTCGCTTCTATTGAAGAAATTAAGGCCTTTTCTCCGAGAGGTATAATCCTTT
CAGGCGGGCCAGCCAGTGTCTATGATGAACATGCCCCTAAAATTCCCAAAGAGATTTTTTCTTTAGGGGTGCCAGTTCTT
GGTATTTGCTACGGTATGCAACTCATGACCCACCTTTTGGGGGGAAAGGTTGAAGCCAGTGCTAAAAGAGAATTTGGTCC
AGCTGAATTAAAAATACTTGATAATAGCGATCTTTTTTACGGCCTGTCTCTTGATAGAAGTTACCGTGTTTGGATGAGCC
ACGGTGACAGAGTAGAAGCCCTCCCTCAAGGCTTTGAAGCCATTGCTGAAAGTGAACATTCTCCTTATGCGGCCATAAAA
AATTCTGAAACTCGCTTATACGGAGTTCAGTTTCATCCTGAAGTAGCTCATACCGAAATAGGCCGAGAGGTGCTTTCTAA
TTTTGTTTTACGCATTTGTGGCTGTAAACCTACCTGGACCATGAAATCTTTTATTGAAAGAGTGGTAGAAGAAATTCGCC
AAAAAGTTGGCCCGGAAGAGAAAGTCATCTGTGCCCTTTCAGGGGGTATTGATTCTACGGTTACGGCGGTTTTGGTTCAT
CGGGCCATAGGGGAGAGATTAGTTTGTATCTTTGTCAATAACGGCCTTTTGCGCAAAGGCGAAGTGGAAAGTGTCTTAAA
TCTTATGGCCTCTCTTGGCCTTAATCTGCGTTATGTGGATGCTTCCGAGCGTTTTCTTGAACGCCTGAAAGGGGTTACTG
ACCCTGAGAAGAAAAGGCAAATTATTGGTCATACTTTTATTGAAATTTTTGAAGAAGAAGCCAAGAAAGTGGGCGATGTA
ACTTACCTGGCCCAAGGAACTCTTTATCCTGACGTAATAGAAAGTGTTTCTTTTAAAGGCCCTTCGGCTACCATAAAGAC
TCATCATAATGTTGGAGCCCTACCTGAACGCATGAAACTTAAACTGATTGAGCCGTTGCGCGAGCTTTTCAAGGATGAAG
TACGCGAGATTGCCCGTGAATTAGGGCTTCCTGAAGACATTATCTATCGTCAGCCTTTCCCTGGCCCAGGGCTTGCCATT
CGTATTTTAGGTGAAGTTACAAAAGATAGGCTTGAAATCTTGAGAGAAGCTGATGCTATCGTGCTTGAAGAGATTAAAAA
AAGCGGCTGGTATCGTAAGGTCTGGCAGAGTTTTGCCGTGCTTTTGCCTATTAGAACCGTAGGTGTTATGGGGGACTACC
GTACCTACGAACACGTTATAGCCATTCGTTGTGTGGATAGTGTGGACGCCATGACGGCTGACTGGACCAGGCTCCCTTAT
GACCTTTTAGCCCGTCTTTCTAACCGCATTATCAACGAAGTGCGTGGCGTCAACCGCGTGGTCTACGATATTTCTTCAAA
ACCGCCAGCTACTATTGAGTGGGAATAA

Protein sequence :
MEQGDRILVLDFGSQTTQLIARRVRELHVYSEIKPCVASIEEIKAFSPRGIILSGGPASVYDEHAPKIPKEIFSLGVPVL
GICYGMQLMTHLLGGKVEASAKREFGPAELKILDNSDLFYGLSLDRSYRVWMSHGDRVEALPQGFEAIAESEHSPYAAIK
NSETRLYGVQFHPEVAHTEIGREVLSNFVLRICGCKPTWTMKSFIERVVEEIRQKVGPEEKVICALSGGIDSTVTAVLVH
RAIGERLVCIFVNNGLLRKGEVESVLNLMASLGLNLRYVDASERFLERLKGVTDPEKKRQIIGHTFIEIFEEEAKKVGDV
TYLAQGTLYPDVIESVSFKGPSATIKTHHNVGALPERMKLKLIEPLRELFKDEVREIARELGLPEDIIYRQPFPGPGLAI
RILGEVTKDRLEILREADAIVLEEIKKSGWYRKVWQSFAVLLPIRTVGVMGDYRTYEHVIAIRCVDSVDAMTADWTRLPY
DLLARLSNRIINEVRGVNRVVYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-148 58
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 8e-149 58
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 8e-149 58
guaA NP_938969.1 GMP synthase Not tested Not named Protein 4e-133 53