Gene Information

Name : lysS (HMPREF0833_10866)
Accession : YP_004621825.1
Strain : Streptococcus parasanguinis ATCC 15912
Genome accession: NC_015678
Putative virulence/resistance : Virulence
Product : lysine--tRNA ligase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 897724 - 899214 bp
Length : 1491 bp
Strand : -
Note : COG: COG1190

DNA sequence :
ATGACTACTGAACATATGGAAGAATTGAATGACCAGCAGATTGTCCGTCGTGAGAAAATGGCGGCCCTTCGTGAACAAGG
AATCGATCCATTTGGGAAGCGATTCGAACGTACTGCAAATTCAGGTCATTTAAAAGAAAAATATTCAGAATTAGATAAAG
AACAACTCCACGACTTGAACGAAACAGCTATTATTGCTGGTCGTCTTGTTACCAAACGTGGAAAAGGAAAGGTTGGCTTT
GCCCATCTTCAAGACCGTGAAGGTCAAATTCAGATCTACGTTCGTAAGGATGCTGTTGGAGAAGAAAACTACGAGATCTT
CAAAAAAGCAGACCTTGGAGATTTCCTTGGTGTTGAAGGGGAAATCATGCGCACAGACATGGGTGAACTTTCGATTAAAG
TAACTCATATCACTCACTTGTCAAAAGCCCTTCGTCCCTTGCCTGAAAAATTCCACGGACTTTCAGACGTTGAAACCATC
TATCGCAAACGTTATTTGGATTTGATTTCAAACCGTGAAAGCTTCGAACGCTTTGTAACCCGTTCAAAAATCATCTCTGA
AATCCGTCGTTATTTAGATGGTCAAGGATTCCTTGAAGTGGAAACACCAGTGCTTCACAATGAAGCTGGTGGTGCGGCTG
CCAAACCATTTATCACTCACCACAATGCACAAAACATTGACATGGTGCTTCGAATCGCGACGGAGCTTCACTTGAAACGT
TTGATTGTTGGTGGGATGGAACGCGTTTACGAAATCGGACGGATCTTCCGTAACGAAGGAATGGATGCCACTCACAACCC
TGAATTCACTTCGATCGAAGTGTACCAAGCTTACGCTGACTTCCACGATATTATGGACTTAACAGAAGGCATTATCCAAC
ATGCTGCGAAAGCGGTCCATGGTGATGGTCCAATTGACTACCAAGGAACAGAGATCAAAATCAATGAACCATTCAAACGG
GTTCATATGGTTGATGCGATTAAAGAAATCACAGGTGTTGACTTCTGGCAAGACATGACCTTTGAAGAAGCTGTAGCACT
GGCAAACGAAAAACATGTACCAGTTGAAAAACACTACACAGAAGTGGGACAAATTATCAATGCCTTCTTCGAAGAATTCG
TTGAAGAAACTTTGACACAACCAACTTTTGTTTATGGTCACCCAGTAGCAGTGTCACCTTTGGCTAAGAAAAATCCAGAA
GACCCACGCTTCACTGACCGTTTCGAACTTTTCATCATGACTAAAGAGTATGCGAATGCCTTTACGGAATTGAATGATCC
GATCGATCAATTGCAACGGTTCGAAGCGCAAGCGCGTGCTAAAGAATTGGGAGATGATGAAGCTACAGGCATCGACTATG
ACTATGTTGAAGCCCTCGAATATGGTATGCCACCAACAGGTGGACTTGGAATTGGTATTGACCGTCTCGTTATGTTGTTG
ACAAATGTAACAACAATTCGCGACGTCCTTCTCTTCCCAACTATGAAATAA

Protein sequence :
MTTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSGHLKEKYSELDKEQLHDLNETAIIAGRLVTKRGKGKVGF
AHLQDREGQIQIYVRKDAVGEENYEIFKKADLGDFLGVEGEIMRTDMGELSIKVTHITHLSKALRPLPEKFHGLSDVETI
YRKRYLDLISNRESFERFVTRSKIISEIRRYLDGQGFLEVETPVLHNEAGGAAAKPFITHHNAQNIDMVLRIATELHLKR
LIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQAYADFHDIMDLTEGIIQHAAKAVHGDGPIDYQGTEIKINEPFKR
VHMVDAIKEITGVDFWQDMTFEEAVALANEKHVPVEKHYTEVGQIINAFFEEFVEETLTQPTFVYGHPVAVSPLAKKNPE
DPRFTDRFELFIMTKEYANAFTELNDPIDQLQRFEAQARAKELGDDEATGIDYDYVEALEYGMPPTGGLGIGIDRLVMLL
TNVTTIRDVLLFPTMK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 7e-110 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_004621825.1 lysine--tRNA ligase VFG1668 Protein 4e-110 47