Gene Information

Name : clpE (HMPREF0833_10072)
Accession : YP_004621031.1
Strain : Streptococcus parasanguinis ATCC 15912
Genome accession: NC_015678
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 65951 - 68221 bp
Length : 2271 bp
Strand : -
Note : COG: COG0542

DNA sequence :
ATGTATATGCTTTGTCAAAATTGTAAAATAAATGAATCAACCATCCATTTATATACAAATGTAAATGGACACCAGCAGCA
AGTAGACCTCTGTCAAAATTGCTATAAAATTATGAAAACAGACCCAAATAACAGCTTCTTGAAAGGCATGACCCAACGGA
GCCAACTGACTGGAGATCCCTTCGAAGATTTCTTCAATAACCTTGGAAACTTCCAAAGTCCACAAGAACCTCAAACACCT
CCAACTCAATCTGGAGTCAGTTATGGAGGTGGCGGTTACGGCCAAAACAATAACCGTAGCGGCAGTCAAGACCCACGTCA
AGCTCGCCCTCAAAAGCCTAAAGGACTATTAGAAGAATTCGGTATCAATGTCACAGAAATTGCCCGCAAAGGGGATATTG
ACCCTGTCATCGGCCGTGATGAAGAAATTATCCGTGTCATCGAAATTCTCAACCGTCGAACCAAGAACAATCCGGTTCTG
ATCGGAGAACCTGGGGTCGGAAAAACTGCCGTTGTGGAAGGCTTGGCCCAAAAAATCGTCGATGGAGACGTTCCTCATAA
ATTGCAAGGAAAAGAAGTCATCCGCCTAGACGTCGTCAGCCTCGTTCAAGGCACAGGTATTCGTGGTCAATTCGAAGAAC
GCATGCAAAAATTAATGGATGAAATTCGTCAACGTGAAGATGTGATTCTTTTCATCGACGAAATCCATGAAATTGTTGGC
GCAGGATCTGCTGGCGAAGGCAATATGGACGCTGGAAATATCCTCAAACCAGCCTTGGCGCGCGGTGAACTCCAATTGGT
CGGTGCTACTACCCTCAATGAATACCGCATCATTGAAAAAGATGCAGCCTTGGAACGTCGGATGCAACCCGTTAAGGTCG
ATGAGCCAACGGTTGAAGAAACCATCACCATCCTCAAAGGCATCCAGAAAAAATACGAAGACTACCACCACGTCCACTAT
ACAGACGGGGCCATCGAAGCGGCAGCTATTCTTTCAAACCGCTACATCCAAGATCGCTTCCTGCCAGACAAGGCCATTGA
TTTGTTGGATGAAGCCGGGTCTAAAATGAACCTGACTCTGAACTTTGTGGATCCAAAAGTTATCGACCAGCGCTTGATTG
AAGCGGAAAACCTCAAAGCTCAAGCGACCCGCGAAGAAGACTTTGAAAAAGCAGCCTACTTCCGCGACCAAATCGCAAAA
TATAAGGAAATGCAAGGTCAACATGTCACCGATCAGGAAACCCCTGTCATCAGCGAAAAAACGATTGAACACATCGTTGA
ACAAAAGACCAATATTCCTGTTGGTGATTTGAAAGAAAAAGAACAATCTCAATTGATCAATCTGGCTTCTGATTTGAAAG
CTCATGTGATTGGTCAAGACGATGCAGTAGATAAAATCGCGAAAGCCATTCGACGCAATCGTGTCGGCCTAGGATCTCCT
AACCGTCCGATCGGAAGCTTCCTCTTTGTCGGACCAACCGGTGTCGGAAAGACCGAATTGTCTAAACAATTGGCGATCGA
GCTCTTTGGCTCTGCAGATAATATGATCCGCTTTGATATGAGCGAATACATGGAAAAACATAGCGTAGCGAAACTAGTCG
GAGCTCCTCCGGGCTATGTGGGCTACGATGAAGCTGGACAACTAACGGAAAAGGTACGTCGCAATCCATACTCTCTCGTT
TTATTGGATGAAGTGGAAAAAGCCCATCCAGATGTCATGCACATGTTCTTGCAAGTCTTGGATGATGGCCGTTTGACAGA
TGGTCAAGGCCGTACCGTCAGCTTTAAAGATACCATTATCATCATGACCTCTAATGCTGGAACCGGCAAGGCTGAGGCCA
ATGTTGGTTTTGGAGCTGCTCGCGAAGGTCGCACCAACTCCGTACTTGGAGAACTCGGGAACTTCTTTAGCCCTGAATTC
ATGAACCGTTTTGATGGCATCATTGAATTCCAACCTCTATCAAAAGAAAACCTTCTTCAAATCGTTACCCTCATGCTGGA
TGAAGTCAATCAACGTCTCGCACAAAATGAGATTCATCTGGATGTGACAGAGAAGGTCAAAGAAAAGTTGGTCGATCTGG
GATACGATCCAAAAATGGGGGCCCGCCCACTCCGTCGTACCATCCAAGACCATATCGAAGATGCCATTACAGATTATTAC
CTAGAACATCCAAGTGAAAAACAACTCAAAGCAGTCATGACCAGCAATGGGAATATTAGCATCAAAGCTACTAAAAAAGC
AGAAAAGAACACTTCTGAAAAGGAAGACTAA

Protein sequence :
MYMLCQNCKINESTIHLYTNVNGHQQQVDLCQNCYKIMKTDPNNSFLKGMTQRSQLTGDPFEDFFNNLGNFQSPQEPQTP
PTQSGVSYGGGGYGQNNNRSGSQDPRQARPQKPKGLLEEFGINVTEIARKGDIDPVIGRDEEIIRVIEILNRRTKNNPVL
IGEPGVGKTAVVEGLAQKIVDGDVPHKLQGKEVIRLDVVSLVQGTGIRGQFEERMQKLMDEIRQREDVILFIDEIHEIVG
AGSAGEGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILKGIQKKYEDYHHVHY
TDGAIEAAAILSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKAQATREEDFEKAAYFRDQIAK
YKEMQGQHVTDQETPVISEKTIEHIVEQKTNIPVGDLKEKEQSQLINLASDLKAHVIGQDDAVDKIAKAIRRNRVGLGSP
NRPIGSFLFVGPTGVGKTELSKQLAIELFGSADNMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRRNPYSLV
LLDEVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKAEANVGFGAAREGRTNSVLGELGNFFSPEF
MNRFDGIIEFQPLSKENLLQIVTLMLDEVNQRLAQNEIHLDVTEKVKEKLVDLGYDPKMGARPLRRTIQDHIEDAITDYY
LEHPSEKQLKAVMTSNGNISIKATKKAEKNTSEKED

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 9e-153 53

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpE YP_004621031.1 ATP-dependent Clp protease VFG0080 Protein 0.0 58
clpE YP_004621031.1 ATP-dependent Clp protease VFG0079 Protein 2e-162 55