Gene Information

Name : polA (HMPREF0833_11582)
Accession : YP_004622541.1
Strain : Streptococcus parasanguinis ATCC 15912
Genome accession: NC_015678
Putative virulence/resistance : Unknown
Product : DNA-directed DNA polymerase I
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0749
EC number : 2.7.7.7
Position : 1705315 - 1707960 bp
Length : 2646 bp
Strand : +
Note : COG: COG0749

DNA sequence :
ATGGAAAAAAAGAATAAATTATTACTCATCGACGGGTCTTCCGTCGCTTTTCGTGCCTTTTTCGCACTCTATCATCAAAT
CGATCGCTTCAAAAATGCCAATGGTCTGCATACCAATGCGGTCTATGGCTTTAATCTCATGTTGAGCCATCTCTTGGAGC
GCATCCAACCAACCCATGTCCTCGTTGCTTTTGATGCAGGAAAGACGACCTTCCGGACGGAGATGTATGCCGACTACAAA
GGGGGCCGTGCAAAAACTCCAGATGAGTTCCGTGAGCAGTTTCCTTTCATTCGTGAGCAATTAGATCATTTGGGAATCCG
CCATTATGAGCTGGCCCAGTATGAAGCGGATGATATTATTGGAACGCTAGATAAGATGGCAGAAACTACCTCGGTGCCCT
TTGATGTGACCATTGTCTCTGGGGATAAGGATTTAATCCAGCTGACAGATGATAATACGGTGGTTGAAATCTCCAAAAAA
GGGGTGGCAGAGTTTGAAGAATTCACTCCAGCCTATCTGAAAGAAAAGATGGGACTGACACCAGAGCAATTTATCGACCT
CAAGGCCTTGATGGGAGATAAGTCGGATAATATCCCGGGTGTCACCAAAATCGGAGAAAAGACCGGGATCAAACTACTCC
TAAAGTACGGCTCTCTTGATGGCATTTACGAGCATATCGACGAGATGAAGGCTTCTAAGATGAAGGAAAACCTCATCAAC
GACAAGGAGCAGGCCTATCTGTCTAAGACTCTCGCAACCATCGATACCAATGCTCCCATTGAAATTGGGCTGGACGATAT
CACCTATACGGGCCCTCATCTAGAAAATCTCGCCAAGTTTTATGAGGAGATGGGCTTCAAGCAACTCCGTCAGGCCTTGG
ATCTCAGTGGAGAAGAAGCAGCTCCTGTAGCTATTGACTATACAGAAGTCGAGCAAGTTGCTTCAGATATGCTCACGGAA
GATAGTTTCTTCCATTTTGAGATTTTTGGGGACAATTACCATACGGAACCCATCATCGGTTTCGCATGGGGGACCAAGGG
TCAGCTCTACGCGAGTACAGATACTGGTCTTTTACAAACACCGATTTTCAAAGAATTTCTCGAAAAAACGCCCCTCAAGG
TCTATGACTTCAAGCGGGCCAAGGTCTTGCTCAGCCACTTGGGCATTACCCTTCAAAATCCCGCGTTTGACAGTCGATTG
GCCAAGTATCTCTTGTCGACCGTAGAGGACAATGAAATTTCAACCATTGCGAGTCTCTATAGTCAGATTGCGCTGCCGTT
GGACGAAGTCGTTTATGGCAAGGGAGTCAAAAGAGCCATCCCAGAAAGGGCGGTCCTATTAGAACATTTGGCACTGAAAG
TCGCTGTTCTACTGGATACCGAAGAGCCCATGGTGGAGCAGTTGCAAGCCCATGACCAGCTAGATTTGCTCTATGATATG
GAGCAACCACTAGCAGCTGTTTTGGCCAAGATGGAAATCGCGGGGATCAAGGTAGAGCGCCAGACCCTAGAAGACATGCA
GGTGGAAAACGAAGTGGTCTTGGAGCGCTTGACCCAAGAAATTTACGAGCTGGCGGGCGAAGAGTTTAACATCAATTCTC
CAAAACAATTGGGGGTCATCCTCTTTGAAAAATTGGAACTTCCTCTTGAATACACCAAAAAGACCAAAACCGGCTATTCA
ACAGCCGTTGATGTCTTGGAACGCCTGGCTCCAATTGCACCGATTGTGTCTAAGATTCTTGAATACCGCCAAATTGCTAA
GATCCAGTCGACTTATGTCATCGGTCTTCAAGATTGGATTTTGGAAGATGGGAAGATCCATACCCGCTATGTACAGGATT
TGACGCAGACGGGCCGTTTGTCCAGCGTGGATCCCAACCTGCAAAACATTCCTGTCCGTTTGGAACAAGGCCGTCTCATC
CGCAAGGCCTTTGTCCCAGAAGAGGAAAATAGTGTCTTGTTGAGTTCGGACTATTCACAGATCGAACTGCGCGTCTTGGC
TCATATTTCGGGAGATGAGCATTTGATTGATGCCTTTAAACATGGGGCAGATATCCATACATCGACTGCTATGCGAGTTT
TCAATATTGAAAAACCAGAAGATGTGACGCCGAACGACCGGCGGAATGCCAAAGCAGTGAACTTCGGTGTGGTTTATGGA
ATTTCCGACTTTGGACTGTCTAACAACCTAGGGATCAGTCGAAAAGAAGCCAAGGCCTACATTGAGACTTACTTCGAACG
CTACCCTGGTATCAAGGACTATATGGAGAGAGTGGTACGGGAAGCGCGTGACAAAGGCTATGTAGAAACCCTCTTCAAGC
GTCGTCGGGAGATTCCAGATATCAATTCTCGCAACTTCAATGTTCGAGGCTTTGCGGAGCGGACGGCTATCAACTCACCA
ATCCAAGGATCTGCAGCAGATATCTTGAAAATTGCCATGATTCACTTGGACCAAGCGCTAGAAGCAGGAGCATACAAGAC
CAAGATGCTTCTTCAGGTGCACGATGAAATCGTTCTGCAAGTACCAAGTGATGAACTGGCAGCGATCAAAGAACTTGTCA
AAGAGACCATGGAATCCGCTATTGAACTTGCAGTACCACTGGAAGCTGATGAGAACGAAGGCAAAACATGGTATGAAGCC
AAATAA

Protein sequence :
MEKKNKLLLIDGSSVAFRAFFALYHQIDRFKNANGLHTNAVYGFNLMLSHLLERIQPTHVLVAFDAGKTTFRTEMYADYK
GGRAKTPDEFREQFPFIREQLDHLGIRHYELAQYEADDIIGTLDKMAETTSVPFDVTIVSGDKDLIQLTDDNTVVEISKK
GVAEFEEFTPAYLKEKMGLTPEQFIDLKALMGDKSDNIPGVTKIGEKTGIKLLLKYGSLDGIYEHIDEMKASKMKENLIN
DKEQAYLSKTLATIDTNAPIEIGLDDITYTGPHLENLAKFYEEMGFKQLRQALDLSGEEAAPVAIDYTEVEQVASDMLTE
DSFFHFEIFGDNYHTEPIIGFAWGTKGQLYASTDTGLLQTPIFKEFLEKTPLKVYDFKRAKVLLSHLGITLQNPAFDSRL
AKYLLSTVEDNEISTIASLYSQIALPLDEVVYGKGVKRAIPERAVLLEHLALKVAVLLDTEEPMVEQLQAHDQLDLLYDM
EQPLAAVLAKMEIAGIKVERQTLEDMQVENEVVLERLTQEIYELAGEEFNINSPKQLGVILFEKLELPLEYTKKTKTGYS
TAVDVLERLAPIAPIVSKILEYRQIAKIQSTYVIGLQDWILEDGKIHTRYVQDLTQTGRLSSVDPNLQNIPVRLEQGRLI
RKAFVPEEENSVLLSSDYSQIELRVLAHISGDEHLIDAFKHGADIHTSTAMRVFNIEKPEDVTPNDRRNAKAVNFGVVYG
ISDFGLSNNLGISRKEAKAYIETYFERYPGIKDYMERVVREARDKGYVETLFKRRREIPDINSRNFNVRGFAERTAINSP
IQGSAADILKIAMIHLDQALEAGAYKTKMLLQVHDEIVLQVPSDELAAIKELVKETMESAIELAVPLEADENEGKTWYEA
K

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
polA YP_281523.1 DNA polymerase I Not tested Not named Protein 0.0 76