Gene Information

Name : clpC (HMPREF0833_11357)
Accession : YP_004622316.1
Strain : Streptococcus parasanguinis ATCC 15912
Genome accession: NC_015678
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease ATP-binding subunit ClpC
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1446441 - 1448870 bp
Length : 2430 bp
Strand : -
Note : COG: COG0542

DNA sequence :
ATGAACTATTCAACAGCACTGTTAGAAAGTATAGAAGCGGCCCAAATACTAGCAGGCCACTATCAGGGGCATACCTTAGA
TACTTGGCATCTCCTGACGGCTATGGCCAATAATCCCTATAGCGTGGCAGGTTCTGTACTGAACGATTATCCTATGCAGA
TCGATGAGTTTCAGGATGCAGCGGAGCATATTACAGGTCAAGCTTTTCAAAGCGACAATCGGTATGAAATCTTCCCATTT
TCTTATCGGATGGAAGCGATTATGAAGCACGCAAGAGAGATTGCCCAGGTCCTTCATGCCAAGACTTTGGGAACAGAGCA
TGTGCTCCTCTCTCTTCTAGCAGACCGTGGGACCTTGGCTAGCCAAGTCATGGAGTTTGCCGGCTTTGCCTTTACAGAGC
AAGACAAGGGAGTTCCTATTGCCTCCCTTCGCAAGAATTTAGAAGACAAGGCAGGCTGGGACAAGAATGATATCAAAGCC
ATTCGGAGTCTTTATCGGGCTCAAAACCCTAACCGCCAAACCATGGGAAATATGATGGGCATGCCCCCAAGCACCAGTGG
AGGTCTTGAAGATTATACCCGTGATTTGACAGAAATGGCGCGGGCAGGCCAGATTGAGCCTGTGATCGGCCGGGATGCAG
AGATTTCACGCATGATCCAAATCCTCAGCCGCAAGACGAAGAACAATCCTGTATTGGTGGGAGAAGCAGGGGTCGGGAAA
ACCGCCCTTGCATTAGGTCTGGCCCAGCGTGTCGCTAGTGGCAATGTTCCAGCTGAAATCGCACAAATGCGTGTCCTGGA
ATTGGATCTCATGAATGTCGTTGCAGGGACGCGCTTCCGTGGAGACTTCGAAGAACGGATGAACAATATCATCCAGGACA
TCGAAGAAGACGGTCACGTGATTCTCTTTATCGATGAACTGCATACCATTATGGGGTCAGGATCCGGCATTGATTCGACC
CTAGACGCAGCCAATATTCTAAAACCAGCCTTGGCACGAGGAACCTTGCGTACAGTTGGAGCAACGACCCAAGATGAGTA
CCAAAAGCATATCGAAAAAGATGCAGCCCTCTCTCGGCGTTTTGCGAAAGTCACCATTGAAGAGCCAAGTGTTGCAGATA
GCATCCAAATTCTCCAAGGCTTGAAAGAGACCTATCAGGACCACCATCATGTGACCATTACTGATGAAGCGATCGAAACA
GCTGTCAAATATGCCCACCGCTATTTGACCAGCCGTCAATTGCCAGATTCAGCCATTGATCTCTTGGATGAAGCGGCAGC
TACCGTACAAAACCGCGATTCCAACGGTCATGTAAAAGAAGAGTTGACCGCCTTGGATCGGGCCTTGATGGATGGCAAGT
GGAAGAAAGCAGCCCAACTCTTAGAAGTAGAGGCCGCTCCCATTGTCTACAAAAAAGAAGTCACTGACCAAGATGTCTTG
GTGACCTTGAGCCAATTATCGGGTATTCCAACTCAAAAACTGACCCAAACCGATGCCAAGAAGTACCTAAACTTAGAAGC
AGAATTGCACAAGCGCGTGATTGGTCAAGACCAAGCCGTTTCGAGTATCAGTCGGGCTATTCGACGCAATCAATCAGGTA
TTCGTAGCAATAAACGTCCGATCGGTTCTTTCATGTTCCTAGGACCTACCGGTGTCGGAAAAACAGAGCTAGCCAAAGCT
TTGGCAGAAGTTCTGTTTGATGATGAATCGGCCCTCATCCGTTTTGATATGAGTGAGTACATGGAAAAATTTGCGGCTAG
CCGCCTCAACGGTGCCCCTCCAGGCTATGTGGGCTACGAAGAAGGAGGCGAATTGACCGAGAAAGTTCGCAACAAACCAT
ATTCAGTTCTCTTATTTGATGAGGTGGAAAAAGCCCACCCAGATATTTTTAATGTCCTTTTGCAAGTCTTGGATGACGGA
GTCTTAACCGATAGCAAAGGCCGGAAGATTGATTTCTCCAATACCATTATCATCATGACCTCAAATCTGGGAGCAACAGC
CCTTCGGGATGATAAGACAGTTGGCTTTGGTGCCAAAGATATTCGCTTTGATCAGGCCAATATGGAAAAACGCATGTTTG
AAGAGTTGAAGAAGACCTATCGTCCAGAGTTTATCAACCGGATTGATGAAAAGGTGGTCTTCCATAGTCTCTCAAGCGAG
GACATGCAGCAGGTGGTGAAAGTCATGGTCAAACCGCTCATCGCGACCTTGGCCGAACAAGACATGACTCTCAAATTCCA
GCCTTCAGCGCTCAAGTTGCTAGCAACCAAAGGCTACGATCCAGAAATGGGAGCTCGCCCACTGCGTCGTGTCTTGCAGA
CCGAAGTGGAAGATCAACTAGCAGAGCTATTGCTGAAAGGGCAAGCCCAAGAAGGGCAAACCATCAAGGTTGGAACGACA
GCCGGAACGATCAAGTTCGAGATTGTCTAG

Protein sequence :
MNYSTALLESIEAAQILAGHYQGHTLDTWHLLTAMANNPYSVAGSVLNDYPMQIDEFQDAAEHITGQAFQSDNRYEIFPF
SYRMEAIMKHAREIAQVLHAKTLGTEHVLLSLLADRGTLASQVMEFAGFAFTEQDKGVPIASLRKNLEDKAGWDKNDIKA
IRSLYRAQNPNRQTMGNMMGMPPSTSGGLEDYTRDLTEMARAGQIEPVIGRDAEISRMIQILSRKTKNNPVLVGEAGVGK
TALALGLAQRVASGNVPAEIAQMRVLELDLMNVVAGTRFRGDFEERMNNIIQDIEEDGHVILFIDELHTIMGSGSGIDST
LDAANILKPALARGTLRTVGATTQDEYQKHIEKDAALSRRFAKVTIEEPSVADSIQILQGLKETYQDHHHVTITDEAIET
AVKYAHRYLTSRQLPDSAIDLLDEAAATVQNRDSNGHVKEELTALDRALMDGKWKKAAQLLEVEAAPIVYKKEVTDQDVL
VTLSQLSGIPTQKLTQTDAKKYLNLEAELHKRVIGQDQAVSSISRAIRRNQSGIRSNKRPIGSFMFLGPTGVGKTELAKA
LAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQVLDDG
VLTDSKGRKIDFSNTIIIMTSNLGATALRDDKTVGFGAKDIRFDQANMEKRMFEELKKTYRPEFINRIDEKVVFHSLSSE
DMQQVVKVMVKPLIATLAEQDMTLKFQPSALKLLATKGYDPEMGARPLRRVLQTEVEDQLAELLLKGQAQEGQTIKVGTT
AGTIKFEIV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 2e-142 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC YP_004622316.1 ATP-dependent Clp protease ATP-binding subunit ClpC VFG0079 Protein 6e-159 46
clpC YP_004622316.1 ATP-dependent Clp protease ATP-binding subunit ClpC VFG0080 Protein 5e-125 46