Gene Information

Name : Mzhil_0707 (Mzhil_0707)
Accession : YP_004615793.1
Strain : Methanosalsum zhilinae DSM 4017
Genome accession: NC_015676
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 773953 - 775431 bp
Length : 1479 bp
Strand : +
Note : COGs: COG0469 Pyruvate kinase; InterProIPR015793:IPR015794:IPR015813:IPR015795:IPR 011037:IPR001697; KEGG: mac:MA3890 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PRIAM: Pyruvate kinase; SPTR: Q8TJ98 Pyruvate kinase; TIGRFAM:

DNA sequence :
TTGCAAGAGAATGAACCTAAAAATGTGCTGGAAGACGTTTCATGTTTTAAGCTTCCTGATCATAAGACCAAAATCGTCTG
TACCCTGGGCCCGGCTTCTTCATCTGAAAATATAATCCGGAAACTAATAATGAAGGGAATGAATATTTCCAGACTTAACT
TTTCCCATGGTAATTTTCAGGATCATAAAGATGTGATTCAGAAGATAAGGAATATTTCCAGAGAGCTATGCATAGAAATT
GCTATTATGGCAGATCTTCCGGGTCCAAAGATCAGAACCGGAAAGCTGGAGACCGAGCCTATACACCTGTCAAAGGGTGA
TGAAGTAATATTGACCACAGAAAATGTTCGGGGAGAAGGCCAGATCATTCCTGTAAATTATAAAAAACTTCCAGAATCTG
TATCCCCTGGAAACTTTATTTACCTCAATGACGGATTTATCCAGCTTGAATGCCTGAAAATTTTAAAAAACAATGTCTAT
TGCAGGGTAATCACTGAAGGTCCACTTTCATCAAATAAAGGTGTTAATCTCCCGGGAATCGATATTGATCTTGAGCCAGT
AACTGAAAATGATCTTAAGGTAATCGATTTTGCACTTGATGCAGGAGTGGATATATTCAGCATTTCATTTGTAGAAAAGG
CAGAAGATATTGAAAAGGTTAGGAATTTTGCTTTGAAGAGGGGCAAGTCGGTTTTTCTTATTGCAAAGATCGAACGTGAG
AAAGCAGTCCGGGATATTGACCGGATTATAGAGGTTTCTGATGGACTTATGATTGCAAGGGGTGATATGGGAGTAGAATT
ACCAATCCAGAATGTGCCCCAGGTCCAAAAGGAACTTATCGCTAAAGCTACAATGAAAGGCATACCTGTAATAACAGCAA
CACATATGCTTGAATCAATGACGGAGAACATCCGGCCTACCCGGGCAGAAGTGACTGATGTTGCAAATGCGATACTTGAT
GGAACTGATGCTGTGATGCTTTCTGGTGAAACTGCAGTAGGAAAATATCCTGTAGAAAGTGTAGAAATGATGTCATCGAT
AGCAAAAGCCTCTGAAGAGTGGAGGGACAGGACCAGATGGGGAATTGAAAGAATAGAGACCCGAATATGTGGTGTTGAAA
TGAATATCGATGATGTTATTTCCCATCATGTCAATGAAGCGGTACAGAGGTTATCGGTCGATTATGTTGTAACTCCCACA
ATGTCGGGACAAACCGCAAGAAGAATCTCCAGGTTCAGGCCATCTACATGGATCCTAGCCTTTAGCCGCTATCCGCTAAC
TGCCCAGAGTCTCACTTTATCTTATGGTGTATTTCCTGTATATGTAAAAAAATTAGAAACAGACTGGGAAAATACAGTCC
TTGGTAAAATGAAAGAGTGGGGAATATATCAGTCTGGAGATATTGTAGTCCTTACTCAGGGACAATCACCTGGCAGGCCG
GGCGGAACAAACCTGCTAAAAATACTTACACTTGTCTGA

Protein sequence :
MQENEPKNVLEDVSCFKLPDHKTKIVCTLGPASSSENIIRKLIMKGMNISRLNFSHGNFQDHKDVIQKIRNISRELCIEI
AIMADLPGPKIRTGKLETEPIHLSKGDEVILTTENVRGEGQIIPVNYKKLPESVSPGNFIYLNDGFIQLECLKILKNNVY
CRVITEGPLSSNKGVNLPGIDIDLEPVTENDLKVIDFALDAGVDIFSISFVEKAEDIEKVRNFALKRGKSVFLIAKIERE
KAVRDIDRIIEVSDGLMIARGDMGVELPIQNVPQVQKELIAKATMKGIPVITATHMLESMTENIRPTRAEVTDVANAILD
GTDAVMLSGETAVGKYPVESVEMMSSIAKASEEWRDRTRWGIERIETRICGVEMNIDDVISHHVNEAVQRLSVDYVVTPT
MSGQTARRISRFRPSTWILAFSRYPLTAQSLTLSYGVFPVYVKKLETDWENTVLGKMKEWGIYQSGDIVVLTQGQSPGRP
GGTNLLKILTLV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 3e-70 41
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 8e-71 41
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 8e-71 41
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 8e-71 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mzhil_0707 YP_004615793.1 pyruvate kinase VFG0479 Protein 4e-71 41