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Name : Mzhil_1435 (Mzhil_1435) Accession : YP_004616498.1 Strain : Methanosalsum zhilinae DSM 4017 Genome accession: NC_015676 Putative virulence/resistance : Unknown Product : HsdR family type I site-specific deoxyribonuclease Function : - COG functional category : V : Defense mechanisms COG ID : COG0610 EC number : - Position : 1546589 - 1549753 bp Length : 3165 bp Strand : + Note : COGs: COG0610 Type I site-specific restriction-modification system R (restriction) subunit and related helicase; InterProIPR004473:IPR014021:IPR001650:IPR007409:IPR 006935:IPR014001; KEGG: mmx:MmarC6_0040 HsdR family type I site-specific deoxyribonuclease DNA sequence : ATGGTCATTCCCAGCATTATCACAGAATCTGAAATTGAAGAACATGCACTGCATTTGCTAGATGAACTCGGATATGAGTG TATCTACGGTCCTGAAATATCACCTGGAGGGAATCTTGTTGAAAGAATGGATTATTCAGATGTAATTTTGAGAAATAGGC TGCAGGATGCTATTGAAAAAATTAATCCCAGCATTCCAGAAAAAGCCAGAGAGGAAGCCATAGAAAAACTTCTTCAGCCA TCTGCACAGGACCTTGTCTTCAATAATCACGAGTTCCATAATCATATTAAAAACGGTATTGATGTTGCATATGAAAGTGG GAATGAAACATATTATGATAAAGTATATCCGGTTGATTTCAATTGTTTAACCAATAATGATTTTCTTGCAGTCAACCAAT TCACAGTACTTGATGGTGAACATAAACGTAGACCGGACCTTATCCTGTTTGTAAACGGCCTTCCATTAGTCGTTATGGAA CTGAAACGACCTGACAATTATACTGACGACTCCGATCTTATTGATGAAGCCTATGACCAGCTGCAAACATATAAAAAAGA AATACCAAACCTTCTTCGATTCAATGAAATTCTAGTTATCAGTGATGGACAGGATGCTAAAGCAGGAACTCTTACATCTA ATAGTAATTTTTTCGCACCATGGAAACATGAGAATGATAACAAGTTCTCAACCGAACCTGAAATTACTACACTTATTAAT AATATGTGTTTACCTGAAGTACTGATTGATATTGTGCAGAACTTCATACTTTTCGAAGATGATAATGGAGTATTACTCAA AAAAATTGCACGATACCATCAATACTATGCTGTAAATAAAGCTGTACATTCAACAAAAGTAGCAGTGAGTCCTGAAGGTG ACAAAAGGTGTGGTGTGGTCTGGCACACTACCGGTGCTGGCAAAAGTATGGAAATGGTATTCTATACTCAAAAAATATCT CGTGATACAACACTTGAAAATCCAACAGTAGTTGTTATCACTGATAGAAATGACTTGGATGACCAGCTTTATGATACATT TTCCAGATGCATAACGTATCTTGGTCAAACTCCAATCCAGGCAGAAACTTCAAAGGATCTAATGGACAAATTAACCCGTA AATCGGGTGGAATAGTATTTACTACGCTCCAGAAATTTTCACCTGATGAAGACAAATATCCTTTACTTTCTGAACGCAAG AATATTATTGTTCTGGCAGATGAGGCACATAGAAGTCAATATGGTCTTGGTGCTAAAATAAACCGGAATACAGGAGAGAA ATCATACGGTTTTGCGAAATATTTGCGTGATGCTCTACCGAATGCATCTTTTATTGGTTTTACAGGTACTCCAATTGAAC TTTCAGATAAAAGCACAAAAGCAATTTTTGGAGATTACATTGATATTTACGACATTGAACAGTCCCTGCACGACCAGGTA ACTGTTCCCATCTCATATGAAAGCAGGTTAGCTAACTTAAAATTGCTTACAAATGATCTGGAAAAACTGGATGCTGGATT TAATGAGATTACAGATGGTGAAGAGTCTGAACGTATAGAGAAACTAAAATCCAAGGAATCCAGTGTTGAAGCAATTTTAA CAACTCCAGAAAACATGGATAAAATTGCTAATGATATAATAAACCACTTTGAATCTCGGAGTAAAGCCATGGATGGAAAA GCCATGATTGTTACTATGAGTCGACACATGGCTGCCCAATTATACGAGTCGATTATAAAATATAGGCCTGATTGGCACGA TGAAGATGATGCAAAAGGTCAAATCAAAGTGATAATTACAGGTAAAGCTTCGGAAACTGAATTAATAGACCATATAAGGC CAAAACAAAAACAAAAACAGATTCAGCAAAGAATGAAGGATCCAGAGGATGAATTAAAAATTGTGATTGTTTGTGATATG TGGCTGACCGGTTTTGATGTTCCCTGTCTGACAACAATGTATTTCCTGAAATATCTAAAAGGTCACAATATAATTCAAGC AATTTCACGTGTAAATAGAGTTTATTTGGATAAACCAGGTGGGCTGGTTGTCGATTATGTTGGTATTCTTTATGATCTCA AACATGCATTAAAGCAATATACAGAAAGTGGTGGTAAAGGTTTACTTGCTGAAGACCAACAGGTTGCCGTAGATTACATG CAGGAGAAGTACGAGCAAATTAATGGAATGCTTCATGGTTTTGATTATAGTAGAGTTTTCAAGGTTCCGGCTGGAGAAAA ACTGGAAATTGTTAGAGAAGGTGCAGATTTCATCTTACAAAAAGATATTCTCATTAACCAGGAAGTAGACCAGAAAATAC GTCCAAAGGGTGATAAGGATTATACTAGAAAGCAGTTTATCAAGTTTACTACAGAACTTTCTAAAGCGTTTGCCCTTGCA TCTCCCAGGCCAGAAACTGAAGCTATTAGAGATGAACTGGGATATTTCCAGTCAGTCAAATCTGTTTTGATTAGTCTTGA CAGAAAGAAAAAAGGATATAAATCTACCAAAGAACTCAAAACAGCAGTTCGTCAACTGGTAAGAGATACGGTTAAAACTG GTGAGATAATTGATGTTTTTGATTTCATGAATATGAAGAAAGAAGGTATAGGTATTCTTGATGAAAAATTCCTAAATGAA GTAAAAAGAATGCCACAGAAAAACCTTGCAGCTGAATTGCTGGAAAAGCTTCTTAATGACAAAATAAAAGCCTATTCTAA AAAGAATATAATCCGCAGTTCAATGTTTTCTGAAAAACTACAGCAATCTGTAAATTCATATCGAAACAAGAATATTACTA ACATTGCGGTTGTCGAAGAGCTAATAAAATTAGCCCATGAAATAAGAAATGAAGAGCAAAGAGAAGGTAATCTTGGACTT TCTACAGAGGAAATTGCATTCTATGACGCTTTAGTTGAAAATGGTAGTGCAGTTGAACAGCTAGGTGACGAGCAGCTAAA AAAGATAGCTACCGAGTTAGTAGAGGTTATTCATAAAAATGCAGGTGTAGATTGGACTGCTAGAAAAACTGTTAAAGCCA AATTAAGATTAAAAGTAAAGAAGCTTCTCAAAAAATACAAATATCCACCAGATCAACAAAAAGCAGCTGTAGAGCTGATT CTCAAGCAGGCACATACATCAGCAGAACAAGTTGCAGTTTTTTGA Protein sequence : MVIPSIITESEIEEHALHLLDELGYECIYGPEISPGGNLVERMDYSDVILRNRLQDAIEKINPSIPEKAREEAIEKLLQP SAQDLVFNNHEFHNHIKNGIDVAYESGNETYYDKVYPVDFNCLTNNDFLAVNQFTVLDGEHKRRPDLILFVNGLPLVVME LKRPDNYTDDSDLIDEAYDQLQTYKKEIPNLLRFNEILVISDGQDAKAGTLTSNSNFFAPWKHENDNKFSTEPEITTLIN NMCLPEVLIDIVQNFILFEDDNGVLLKKIARYHQYYAVNKAVHSTKVAVSPEGDKRCGVVWHTTGAGKSMEMVFYTQKIS RDTTLENPTVVVITDRNDLDDQLYDTFSRCITYLGQTPIQAETSKDLMDKLTRKSGGIVFTTLQKFSPDEDKYPLLSERK NIIVLADEAHRSQYGLGAKINRNTGEKSYGFAKYLRDALPNASFIGFTGTPIELSDKSTKAIFGDYIDIYDIEQSLHDQV TVPISYESRLANLKLLTNDLEKLDAGFNEITDGEESERIEKLKSKESSVEAILTTPENMDKIANDIINHFESRSKAMDGK AMIVTMSRHMAAQLYESIIKYRPDWHDEDDAKGQIKVIITGKASETELIDHIRPKQKQKQIQQRMKDPEDELKIVIVCDM WLTGFDVPCLTTMYFLKYLKGHNIIQAISRVNRVYLDKPGGLVVDYVGILYDLKHALKQYTESGGKGLLAEDQQVAVDYM QEKYEQINGMLHGFDYSRVFKVPAGEKLEIVREGADFILQKDILINQEVDQKIRPKGDKDYTRKQFIKFTTELSKAFALA SPRPETEAIRDELGYFQSVKSVLISLDRKKKGYKSTKELKTAVRQLVRDTVKTGEIIDVFDFMNMKKEGIGILDEKFLNE VKRMPQKNLAAELLEKLLNDKIKAYSKKNIIRSSMFSEKLQQSVNSYRNKNITNIAVVEELIKLAHEIRNEEQREGNLGL STEEIAFYDALVENGSAVEQLGDEQLKKIATELVEVIHKNAGVDWTARKTVKAKLRLKVKKLLKKYKYPPDQQKAAVELI LKQAHTSAEQVAVF |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| hsdR | BAH57699.1 | type I restriction-modification system endonuclease homologue | Not tested | Type-VII SCCmec | Protein | 0.0 | 46 |
| hsdR | BAD24840.1 | type I restriction-modification system endonuclease homologue | Not tested | Type-V SCCmec | Protein | 0.0 | 46 |
| hsdR | YP_251977.1 | type I restriction-modification system restriction subunit | Not tested | SCCmec | Protein | 0.0 | 46 |
| api52 | CAF28526.1 | hsdr-like Type I restriction enzyme | Not tested | YAPI | Protein | 0.0 | 44 |
