Gene Information

Name : metB (CRES_0467)
Accession : YP_004604994.1
Strain : Corynebacterium resistens DSM 45100
Genome accession: NC_015673
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 558685 - 559860 bp
Length : 1176 bp
Strand : +
Note : Cystathionine beta-lyases/cystathionine gamma- synthases

DNA sequence : 
ATGAATCAGCCGCGCCACCCCGGTTTCGATACAAACGCTATCCATGCGGGATATGAACCGGATGGGCACATGGGTTCGAT
CAACGTACCTATCTATGCCTCCACCACGTTTGCCCAGAATGCCCCAAATGATCTGCGAGGCGGATTCGAGTACGGGCGCG
TGGCAAACCCCACCGTCACTTCGCTAGCCAACACAATTGCTGCCCTTGAGGGCGCTAGTCACGGCAAGGTTTTTGCTTCG
GGAATGGCCGCGACCGATCTGCTGCTACGCGCTATTTTGCGGCCGGGTGACCATTTGGTGATGGGCCACGATGCTTATGG
GGGAACGTATCGACTGATTAACACTGTCTTCGTGGAATGGGGCGTGGAATTCTCCGTGGTGGATACCACCAAGCCCGATC
AAGTCGCGGCTGCTTTGCAGTCGAATACTAAGCTCGTCTGGCTGGAGACCCCCACAAATCCGCTGCTGGCAATCACGGAT
ATCGCTGCCATTGCCGAGGTGCTGGATGCGCATTCATTAGGTGATCGCCCTCGACTGATCGTAGATAACACCTTCGCGTC
CCCGTACCTGCAGCGCCCGCTGGATCTCGGCGCGGATGTCGTTTTGCACTCCACTACCAAATACATCGGTGGTCACTCGG
ATGTTATTGGTGGCGCGGTCGTCTCCAACGATGCGCACCTCGATGAGGCGCTCGACTTCCTTCTAGGGGGAGTGGGCCCT
ACTTCTTCTCCCTTCGACGCCTACCTCACTGCCCGCGGAGTGAAAACCCTAGGCGTACGGATGGACCGGCACTGCGCAAA
TGCGCAGTCAGTGGCAGAATTTTTGGATGCACGTCCTGAGGTAACCGAGGTTTTGTACCCCGGATTGGAATCGCACCCCG
GTCACGAGGTCGCAGCTCGGCAGGGCACGGGCAAGGGTTTTGGCGGAATGATCTCCGTGCGATTTGGCGCGGAAGAAAAG
GCGCTTGCTTTTTGCCAGACAACGAAGCTCATCTGTCTGGCTGAATCCCTTGGCGGAGTGGAAAGCCTGTTGGAGCACCC
CGCTATGATGACGCACCAATCCGTTGCCGGCTCTCAGCTGGAAGTTCCGCGAGACTTAGTCCGGATCTCCATCGGCATCG
AAAACGAAGAGGACCTGCTGGCGGATGTGCAGCAGGCCCTAGAACAGCTGCCTTAA

Protein sequence : 
MNQPRHPGFDTNAIHAGYEPDGHMGSINVPIYASTTFAQNAPNDLRGGFEYGRVANPTVTSLANTIAALEGASHGKVFAS
GMAATDLLLRAILRPGDHLVMGHDAYGGTYRLINTVFVEWGVEFSVVDTTKPDQVAAALQSNTKLVWLETPTNPLLAITD
IAAIAEVLDAHSLGDRPRLIVDNTFASPYLQRPLDLGADVVLHSTTKYIGGHSDVIGGAVVSNDAHLDEALDFLLGGVGP
TSSPFDAYLTARGVKTLGVRMDRHCANAQSVAEFLDARPEVTEVLYPGLESHPGHEVAARQGTGKGFGGMISVRFGAEEK
ALAFCQTTKLICLAESLGGVESLLEHPAMMTHQSVAGSQLEVPRDLVRISIGIENEEDLLADVQQALEQLP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-73 44
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-74 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metB YP_004604994.1 cystathionine gamma-synthase BAC0207 Protein 3e-63 42