Gene Information

Name : aldA (CRES_0300)
Accession : YP_004604827.1
Strain : Corynebacterium resistens DSM 45100
Genome accession: NC_015673
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.3
Position : 353291 - 354811 bp
Length : 1521 bp
Strand : -
Note : NAD-dependent aldehyde dehydrogenases

DNA sequence :
ATGACCGTGTATGCCGATCCCGGAACCTCGGGTGCAATCGTCAATTTCGACAAGCAATACGAAAACTTCATCGGCGGAAA
GTGGACTCCACCAGTAGGTGGCGAGTACCTCGATAACGTCAGCCCGATCAACGGCGAAGTGTTCTGTCGCGTGCCACGTT
CCCAAAAGGAAGACATCGAAAAAGCGTTAGATGCTGCTCACGCGGCCAAAGAAGAATGGGGGCGCACCAGCCCGCAGGAA
CGCGGCAATATTTTGCTGAAAATTGCGGATCGGCTCGAGGATAACCTTGAGAAGCTCGCGGTTGCCGAAACTTGGGATAA
CGGCAAGGCAGTGCGCGAAACCCTCGCTGCTGACCTCCCACTCGCCGTCGATCACTTCCGCTACTACGCAGGTGCGATCC
GCGCGCAAGAGGATCGCACCAGTCAGATCGATGTTGATACAGTCGCGTACCACTTCCGTGAACCATTGGGTGTAGTTGGC
CAAATCATCCCGTGGAACTTCCCGATCCTGATGGCGGCGTGGAAACTCGCGCCCGCCTTGGTCGGCGGTAACTGCATCGT
CCTTAAGCCCGCCGAACAAACCCCAGCCAGCATCTTGTTGGTCGTTGAGCTCATTCAAGATCTGTTGCCAGCCGGGGTTC
TCAACGTTGTGAATGGTCTCGGCGAAGAAGCCGGTGCAGCCCTAACCGCCAGCGATCGTGTCGCCAAGATCGCCTTTACC
GGCTCCACTCAGGTCGGCCAGATTATCAACAAGGCTGTGGCTGAAAAGCTCATCCCCGTCACTCTTGAACTGGGTGGTAA
GAGTCCGTCCATTTTCTTCAAGGACGTCATGGATGAAGACGATGACTTCCGCGCCAAGTGTGTGGAAGGCTTGGCCATGT
TCGCGCTCAACCAAGGCGAAGTGTGCACCTGCCCTTCCCGCGCACTGGTTCATGAGGATATCGCCGAAGAGTTCCTCGAC
CTCGCCGTGCAACGCGTGAAGAACATCAAGATTGGTAACCCGCTGGATACCGAAACCATGATGGGGGCTCAGGCTTCGGA
AGAGCAGATGGACAAGATCACTGGCTACCTGCAGTCCGGCCCAGAAGAAGGCGCGGAAGTCCTCACCGGTGGAGGCATCA
ACAAGATTGAAGGTCGCGATGGTGGCTTCTACATTGAACCCACCATCTTCAAAGGCACCAACAATATGCGCCTCTTCCAA
GAGGAGATTTTCGGCCCCGTCCTCGCGGTGACAACGTTCAAGGACTTCGACGATGCCATCCGTATCGCGAACGATACGGA
GTATGGCCTAGGCGCCGGCGTATGGTCCCGTAACGGTAACACTGCATACCGGGCCGGGCGAGCCATCCAATCCGGGCGCG
TGTGGGTGAACAACTACCACAACTACCCAGCACACGCAGCGTTCGGTGGTTACAAGAAATCCGGAATCGGCCGCGAAACC
CACCTGATGATGCTCGATCACTACCAGCAGACCAAGAATCTGTTGTGGTCCTACAGCGAGAAGCCAACGGGGCTGTTCTA
A

Protein sequence :
MTVYADPGTSGAIVNFDKQYENFIGGKWTPPVGGEYLDNVSPINGEVFCRVPRSQKEDIEKALDAAHAAKEEWGRTSPQE
RGNILLKIADRLEDNLEKLAVAETWDNGKAVRETLAADLPLAVDHFRYYAGAIRAQEDRTSQIDVDTVAYHFREPLGVVG
QIIPWNFPILMAAWKLAPALVGGNCIVLKPAEQTPASILLVVELIQDLLPAGVLNVVNGLGEEAGAALTASDRVAKIAFT
GSTQVGQIINKAVAEKLIPVTLELGGKSPSIFFKDVMDEDDDFRAKCVEGLAMFALNQGEVCTCPSRALVHEDIAEEFLD
LAVQRVKNIKIGNPLDTETMMGAQASEEQMDKITGYLQSGPEEGAEVLTGGGINKIEGRDGGFYIEPTIFKGTNNMRLFQ
EEIFGPVLAVTTFKDFDDAIRIANDTEYGLGAGVWSRNGNTAYRAGRAIQSGRVWVNNYHNYPAHAAFGGYKKSGIGRET
HLMMLDHYQQTKNLLWSYSEKPTGLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-140 63
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 2e-148 61
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 2e-148 61
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 2e-148 61
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 4e-148 61

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
aldA YP_004604827.1 aldehyde dehydrogenase VFG0082 Protein 4e-141 63