Gene Information

Name : Flexsi_0362 (Flexsi_0362)
Accession : YP_004602618.1
Strain : Flexistipes sinusarabici DSM 4947
Genome accession: NC_015672
Putative virulence/resistance : Virulence
Product : polysaccharide biosynthesis protein CapD
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1086
EC number : -
Position : 383216 - 385069 bp
Length : 1854 bp
Strand : -
Note : PFAM: Polysaccharide biosynthesis protein; COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: wsu:WS0037 aminotransferase-like protein; PFAM: DegT/DnrJ/EryC1/StrS aminotr

DNA sequence :
TTGAGCAATATTTTAAGACCCACTCAGATCAAAAGGGCTTTGTTTTTTCTCATCGGTGATTTGATACTTCTCACTTTCAG
CTATTATCTGTCTTTTCTTTTAAGATTCGATTTTAACTTTAGTCATGATTTTGTATTTCAAGCGAATATTACATTTATAC
CCGTTGTTCTGATAAAAATTTTTCTTCTCAACTTGTTCGGTCAGTATAAAATCAGCTGGAAATTTGTCAGTCTGAGCGAA
TTTTACAAAATTACAGTATCTTTCTTTATATTTTTTGTCATCTTTTTTGCTGTGGATATTTTATTTTTGATGTTTAGAGA
TACTGTGCTTGTACCCCGTTCTATCCCTATCCTGGATTTTATTATTTCAACTCTTCTCATCTGCACGTTTAGAATTTCAA
AACGTATTTACAATGAGATTCTTTTTACCAACTCATCCTCCAGAACAAAAACACTCATTGTAGGTGCCAATACTCAGGGT
GAAAGGATCGCCCGTGAACTGCTGCGGGATGAAAAACAGGTTTTTTATCCTTATTGCTTTATTGACAACGATATTACAAA
AAAGGGAGTAATGATATCAAATATCCCCGTATATGTGGGATATGAAAAGATATATGAAATTTTGGATAAGAATATCATTG
AAGCCGTTATTATTGCCAACCCTTCCATTACTCACAAAGAAATCAGGGAAATAGTTGAGGCGGCTAAGCAGCATAATATA
AATGAGATTAAGATTGCTCCTTCTATTTACCAAATGAGAGACAGAACACTTGATGTAACGGATATCCGGGATATTAATGT
TGAGGATTTGCTTGCGAGAAATGTTGTGCAGGTGGAAAATAATAAAATTCGGGATATGGTTGAAAACAGGTCAGTATTGA
TAACAGGTGCGGGCGGATCGATTGGCTCGGAAATAGCGAGACAAATTATGCAATTTTCCCCTGTGAGGATTGTATGTTTT
GAGATTGATGAGACGGAACTTTTTGATTTAACAAATGAGCTTTTGCTGTTAAATAACGGAAATTCCACTACTGTTGTCCC
CTGGGTGGGTGATATAAGAAATAAAAGTACGCTTGATAATCTTTTTAAAAAGGAGAAAATCGATATAATTTTTCATTCGG
CTGCGTATAAACATGTCCCGCTAATGGAATATTTTCCCAAAGAAGCATTTTGTACAAATGTAATGGGTACATATTATCTT
GCACAAACCGCTTCGGCTTATGGAGTTGAAAAGTTTATAAACATATCCACGGACAAAGCTGTCAGCCCGACAAGCATAAT
GGGTGCCACAAAGAGAATATCGGAAATGATTTTAACTACCCTTGATAAGAAAAGCAGCGATACCGATTTTATCTCGGTAA
GATTCGGTAATGTGCTGGGGAGCAGAGGCAGTGTCGTTCCTGTTTTCCTGAATCAGATAAAACAGGGAGGACCTGTCACG
GTAACACATCCGGAAATTAAAAGATACTTTATGACAATTCCCGAAGCCGTTTTGCTTGTGTTTCAGGCAGCATCTATGGG
GGAAGGCGGAGAGGTGTTTGTGCTTGATATGGGCGAACCGGTTAAAATAGTTTCAATTGCTGAAGAGCTTATTAAACTCC
AAAATCTGGAGCCTTATGAAGATATAGAAATTAAATTTACAGGATTAAGACCGGGGGAAAAGCTGTTTGAGGAGATACTG
ACAGCCGAAGAGGGTACAAATACAACAACCCACGAAAAAATATATATTGCTAGAGGAAGCACTGAATATGATTTTAATAC
ATTAACATCAAACATACAGGGTATTATGGAATGCTGTACCGATGAGGAAATAATCGCCAGAATCAAACAGCTTGTGCCTT
TTTATACAGGATAA

Protein sequence :
MSNILRPTQIKRALFFLIGDLILLTFSYYLSFLLRFDFNFSHDFVFQANITFIPVVLIKIFLLNLFGQYKISWKFVSLSE
FYKITVSFFIFFVIFFAVDILFLMFRDTVLVPRSIPILDFIISTLLICTFRISKRIYNEILFTNSSSRTKTLIVGANTQG
ERIARELLRDEKQVFYPYCFIDNDITKKGVMISNIPVYVGYEKIYEILDKNIIEAVIIANPSITHKEIREIVEAAKQHNI
NEIKIAPSIYQMRDRTLDVTDIRDINVEDLLARNVVQVENNKIRDMVENRSVLITGAGGSIGSEIARQIMQFSPVRIVCF
EIDETELFDLTNELLLLNNGNSTTVVPWVGDIRNKSTLDNLFKKEKIDIIFHSAAYKHVPLMEYFPKEAFCTNVMGTYYL
AQTASAYGVEKFINISTDKAVSPTSIMGATKRISEMILTTLDKKSSDTDFISVRFGNVLGSRGSVVPVFLNQIKQGGPVT
VTHPEIKRYFMTIPEAVLLVFQAASMGEGGEVFVLDMGEPVKIVSIAEELIKLQNLEPYEDIEIKFTGLRPGEKLFEEIL
TAEEGTNTTTHEKIYIARGSTEYDFNTLTSNIQGIMECCTDEEIIARIKQLVPFYTG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cap1D AAA64643.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 7e-76 44
SSP0063 YP_300153.1 capsular polysaccharide biosynthesis protein Not tested SCC15305cap Protein 1e-73 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Flexsi_0362 YP_004602618.1 polysaccharide biosynthesis protein CapD VFG1300 Protein 5e-73 43
Flexsi_0362 YP_004602618.1 polysaccharide biosynthesis protein CapD VFG0029 Protein 1e-71 42