Gene Information

Name : Flexsi_2146 (Flexsi_2146)
Accession : YP_004604336.1
Strain : Flexistipes sinusarabici DSM 4947
Genome accession: NC_015672
Putative virulence/resistance : Unknown
Product : replicative DNA helicase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0305
EC number : -
Position : 2295586 - 2296959 bp
Length : 1374 bp
Strand : +
Note : PFAM: DnaB-like helicase N terminal domain; DnaB-like helicase C terminal domain; TIGRFAM: replicative DNA helicase; COGs: COG0774 UDP-3-O-acyl-N-acetylglucosamine deacetylase; HAMAP: UDP-3-O-acyl N-acetylglucosamine deacetylase; InterPro IPR004463; KEGG:

DNA sequence :
ATGGCTAACGGTTATACTAAGAATTACAGAAACAATGCGAGTTATTCTGACAATAACAGTCCGGCTATAAAGAAGCCTCC
TTACAGTATGGAGGCCGAACAGGCTGTACTTGCTTCTATACTTATTGACGATAAGGCGCTTGATAAAATTGTGCATCTTC
TGGGGGTCAGTGATTTTTATTACCCCCCTCATAAAATAATATTTAAAGAACTTATGGAGCTTGCCCATAACAATAAGCCG
TTGGATATTGTAACCCTTGTTAGTTCCCTCAATGACAAAGAGCTCACAGAAAAAGCAGGCGGGGTGGATTATATTTCTGA
GCTGGTGAATATTATACCCAATTCGGCCAATATTGTTCATTACGCCAATATGGTAAAAGACAAAGCGCTGTTGCGGGCAT
TAATCGAGTTTAGCTCAGATATTGCCGAAAAGTCCTATTCATATACCGGTGAAATCAGCAGTCTGGTTGACGAAGCTGAG
AAGCATATTTTCAGTCTGGCTGAATTCAAACTTAAGAATGAAGTTCAGCCGATAGGTGTGGTAATAAAGGATACTTTTGA
AATTTTGGAAAGTCTTTACGGCAGGAACGAACAGATTACCGGAATACCAACCGGATTTATGGATCTGGACAGGCTAACAA
ACGGTCTTCAGAAGTCTGATCTTATTATTGTAGCCGGCAGACCCGGTATGGGCAAGACTGCTTTTGCAATGAATCTCGCC
CTGAACACCTGCAGCAAGTATGACAGGTCGGCAGCTGTTTTTTCTTTGGAGATGTCTTCCGGACAGCTTGTGCAAAGGCT
TTTGTCTTCCGAAGCGAAAATAGAGTCTACAAAGCTGCGTAACGGAAGGCTAAACAATGATGAATGGCAGAGACTTGCCA
GTGTTGGTTCGGAGCTGAATGATTTGAATCTGTTTCTTGATGACACACCTGCTATTTCATCTATGGAGCTTAGAGCGAAA
TGCAGAAGGCTTAAAAGGGAATATGATCTGGATGTGGTTATAGTTGATTATCTTCAGCTTATGTCAGGCAGCAGAGCTGA
AAGCAGGGAACAGCAAATCTCTGAAATTTCGAGGGCGCTGAAAGCCCTTGCAAAAGAGTTGAATATTCCGGTAATAGCAC
TTTCCCAGCTTAACAGGGGTGTTGAAAACAGAACGGATAAGAGACCTGTCCCCTCTGATTTGAGAGAGTCCGGGGCTATT
GAACAGGATGCAGATCTTATTATGTTTTTATATCGTGACGAGGTGTATCATCAGGATACAAAGCTTCCCGGAGTTGCCGA
ACTTATTGTGGCCAAGCATAGAAACGGTCCTACTGATACTATAAAGCTTGCTTTTCTTGAAGAGTACACCCGCTTCGAAA
ATGCTGAGATATAA

Protein sequence :
MANGYTKNYRNNASYSDNNSPAIKKPPYSMEAEQAVLASILIDDKALDKIVHLLGVSDFYYPPHKIIFKELMELAHNNKP
LDIVTLVSSLNDKELTEKAGGVDYISELVNIIPNSANIVHYANMVKDKALLRALIEFSSDIAEKSYSYTGEISSLVDEAE
KHIFSLAEFKLKNEVQPIGVVIKDTFEILESLYGRNEQITGIPTGFMDLDRLTNGLQKSDLIIVAGRPGMGKTAFAMNLA
LNTCSKYDRSAAVFSLEMSSGQLVQRLLSSEAKIESTKLRNGRLNNDEWQRLASVGSELNDLNLFLDDTPAISSMELRAK
CRRLKREYDLDVVIVDYLQLMSGSRAESREQQISEISRALKALAKELNIPVIALSQLNRGVENRTDKRPVPSDLRESGAI
EQDADLIMFLYRDEVYHQDTKLPGVAELIVAKHRNGPTDTIKLAFLEEYTRFENAEI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed ABR13456.1 replicative DNA helicase Not tested PAGI-5 Protein 8e-84 45
dnaB2 YP_001402701.1 replicative DNA helicase Not tested YAPI Protein 5e-79 43
api2 CAF28476.1 putative DNA binding protein with DNA-dependent ATPase activity Not tested YAPI Protein 2e-79 43
STY4522 NP_458617.1 DNA helicase Not tested SPI-7 Protein 2e-80 43
t4227 NP_807829.1 DNA helicase Not tested SPI-7 Protein 2e-80 43
PMI2640 YP_002152342.1 DNA helicase Not tested Not named Protein 1e-78 42
dnaB CAI36044.1 replicative DNA helicase DnaB Not tested PPHGI-1 Protein 1e-68 41
dnaB2 YP_001007676.1 putative DNA helicase Not tested YAPI Protein 2e-73 41