Gene Information

Name : Halxa_3908 (Halxa_3908)
Accession : YP_004598392.1
Strain : Halopiger xanaduensis SH-6
Genome accession: NC_015666
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 3260293 - 3262050 bp
Length : 1758 bp
Strand : +
Note : TIGRFAM: Pyruvate kinase; KEGG: htu:Htur_0844 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, alpha/beta; PEP-utilising enzyme, mobile region

DNA sequence :
ATGAGAAACGCGAAGATCGTCTGTACCCTCGGTCCGGCCTCGAGCGACCGCCGGACCATCCGCGAGCTGGCCGACGCCGG
CATGTCCGTCGCGCGGCTGAACGCCAGCCACGGCAGCCCCGAAGACCGAGCCGAACTCGTCGACCGCGTCCGCGACGTCG
ACGAGGAGCGCGACGAGCCGGTCGCCGTCATGCTCGACACGCAGGGCCCCGAGATCCGAACCGCTCCCCTGCCGGACGGC
GAAACCGTCACCCTCGAGACGGGCTCGGAGATCGAGTTCGTCGAGGGCGACGAGGCCTCGTCCGACCGCGTCGGCCTCTC
CCTGCCGATCGACGAGGTCGAGGAAGGCGACCGCATCCTGCTCGACGACGGCCTCATCGAGACCACCGTCCTCGAGCGCG
ACGGCGGCGCGATCCGAGCCCGAGTCGACACCGGCGGCGAACTGGCCGGCCGGAAAGGCGTCAACGTCCCCGGCGTCGAT
CTGGATCTGGACGTCGTCACCGAGAAGGATCGGCAGGATCTCGAGCTGGCCGCCGAGAAGGAGGTCGACTTCGTCGCGGC
GAGTTTCGTCCGCGACGCCGAGGACGTCTACGAGGTCAGCGAGGTCCTCGAGGAGTTCGACGCCGAGATTCCGATCATCT
CGAAGATCGAACGCGCCGGCGCCGTGGAGAACCTCGACGAAATCATGGAAGCCTCCTACGGCATCATGGTCGCGCGCGGC
GACTTGGGCGTCGAGTGTCCCATGGAGGACGTCCCGATGATTCAAAAGCGGATCATCCGACAGTGCCGCGAGGCCGGGCT
CCCGGTCATCACCGCGACGGAGATGCTCGACTCGATGGTCCACGCCCGCCGACCCACCCGCGCGGAGGCCTCGGACGTGG
CCAACGCCGTCCTCGACGGCACCGACGCCGTGATGCTCTCGGCGGAGACGGCCGTCGGCGACCACCCCGCCGAGGTCGTC
GACGCGATGGACAGCATCATCCGCGAGGTCGAGGCGTCCGGCGAGTACGCCGAACTCTTGGAGCAGCGCGTGCCCGCTGC
CGGCGAGGCCCGAACCGACGCGCTTGCCCGCTCCGCCCGGTTCCTCGCGCGCGACATCAGCGCGGACGCGGTCGTGGCCG
CGACCGAGTCGGGTTACACGGCGCTGAAGACCGCGAAGTACCGGCCCGGCGTCCCGGTCGTCGCCTCGACGCCGAGCCAC
GAGGTTCGCCGTCGACTCGCGCTCTCGTGGGGCGTGACGCCGCTGTACGCCCGCGTCTCCGATCAGGGGGCCGGCGCCGT
CGTCGAGCGCGCCGTCCAGGCAGCCCTCAACGCCGGCGTCGCGGAGAGCGGCGACACCGTCGTCGTCCTCTGCGGCATGA
TGACCGAACTCGAGGGCGCGAACACGACGAACATGCTGAAGGTCCACGTCGCCGCGGAGGCGCTGACGACGGGCCGGGTC
GTCGTCGAAGGTCGCGCGACGGGGCCGCTCGTCCACCTGACCGACGGCGACCTCTCGGACGTCCCGGACGGCGCGATCGT
CGCCGTCCCCTCCGATTTCGACGAGGAGTTCGAGGGCGACCTCGAGAAGATTGCCGGTATCATCGACGCCCAGCGGGGCA
TGACCGGCTATCCGTCGCTGGTGGCCCGCGAGATGGATCTCCCGATGATCAGCGGCGCGGACGTCTCCGAGGAGGCCGAG
GGGGAGACCGTGACGATCGACGCCGAACGCGGCGTCGTCTACGGCGGCGATATCGGCGACCAAGCGGTGCGAGAGTAA

Protein sequence :
MRNAKIVCTLGPASSDRRTIRELADAGMSVARLNASHGSPEDRAELVDRVRDVDEERDEPVAVMLDTQGPEIRTAPLPDG
ETVTLETGSEIEFVEGDEASSDRVGLSLPIDEVEEGDRILLDDGLIETTVLERDGGAIRARVDTGGELAGRKGVNVPGVD
LDLDVVTEKDRQDLELAAEKEVDFVAASFVRDAEDVYEVSEVLEEFDAEIPIISKIERAGAVENLDEIMEASYGIMVARG
DLGVECPMEDVPMIQKRIIRQCREAGLPVITATEMLDSMVHARRPTRAEASDVANAVLDGTDAVMLSAETAVGDHPAEVV
DAMDSIIREVEASGEYAELLEQRVPAAGEARTDALARSARFLARDISADAVVAATESGYTALKTAKYRPGVPVVASTPSH
EVRRRLALSWGVTPLYARVSDQGAGAVVERAVQAALNAGVAESGDTVVVLCGMMTELEGANTTNMLKVHVAAEALTTGRV
VVEGRATGPLVHLTDGDLSDVPDGAIVAVPSDFDEEFEGDLEKIAGIIDAQRGMTGYPSLVAREMDLPMISGADVSEEAE
GETVTIDAERGVVYGGDIGDQAVRE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 2e-62 41
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 2e-62 41
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 1e-62 41
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 5e-62 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Halxa_3908 YP_004598392.1 pyruvate kinase VFG0479 Protein 7e-63 41