Gene Information

Name : EAE_21670 (EAE_21670)
Accession : YP_004594516.1
Strain : Enterobacter aerogenes KCTC 2190
Genome accession: NC_015663
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : -
Position : 4636234 - 4638183 bp
Length : 1950 bp
Strand : -
Note : COG0550 Topoisomerase IA

DNA sequence :
ATGCGGTTGTTTATTGCAGAAAAACCGAGTCTCGGTCGCGCTATCGCCGATGTGTTGCCGAAACCGCATCGCAAAGGCGA
TGGCTTTATTGAGTGCGGCAACGGGCAGGTGGTCACCTGGTGTATCGGCCACCTGCTGGAGCAGGCGCAGCCGGATGTTT
ACGACGGGCGCTATGCGCGCTGGAACCTGCTCGACCTGCCCATCGTTCCGGAAAAGTGGCAACTGCAACCAAAACCGTCG
GTCACCAAACAGCTGAACGTCATCAAGCGCCTGCTTGGCGAGGCGCAGGAAGTGGTTCACGCGGGCGACCCGGATAGAGA
AGGGCAACTGCTGGTCGATGAGGTGCTGGACTACCTGCAGCTGGCGCCGGAAAAGCGCCAGCAGGTGCAGCGTTGCCTTA
TTAACGACCTCAACCCACAGGCGGTTGAGCGGGCGATTAACCGCCTGCGCGCGAATAGCGAGTTTGTCCCGCTGTGCGTG
TCGGCGCTGGCCCGCGCTCGCGCCGACTGGCTGTATGGCATCAACATGACCCGCGCCTACACCATTCTCGGGCGTAATGC
CGGCTATCAGGGAGTGTTGTCAGTTGGTCGCGTACAGACGCCGGTGTTGGGGCTGGTGGTGCGTCGCGATGAAGAGATCG
AGAACTTCGTCGCCAAAGATTTCTTTGACGTCAAAGCGCATATTGTCACGCCGCAAGACGAGCGGTTTATCGCCACCTGG
GTGCCGAGCGAAGCCTGCGAACCCTATCAGGATGAAGAGGGGCGTTTACTGCATCGCCCGCTGGCCGAGCATGTGGTTAA
ACGCATTGAAGGCCAGCCGGCAATCGTGACCGGTTATAACGATAAGCGCGATTCCGAACCGGCGCCGCTACCGTTTTCAC
TGTCGGCGTTACAGATCGAAGCGGCCAAACGTTTCGGCTTCAGCGCCCAGAACGTGCTGGATATCTGCCAGAAGCTGTAT
GAGACCCACAAACTGATTACCTATCCGCGCTCGGATAGCCGCTACCTGCCGGAGGAACATTTTGCCGGCCGCCATGCGGT
ACTGAATGCGATTAGCGTCCATGCGCCGGATCTGCTGCCGCAGCCGGTGATGGATCCGGAGATCCGCAACCGCTGTTGGG
ATGATAAAAAGGTCGATGCGCACCACGCCATTATCCCGACCGCGCGCAGCAGTCAGGTCAAACTCAACGATAACGAAGAG
AAGGTATACAACCTGATCGCTCGTCAGTATCTGATGCAGTTCTGCCCGGATGCGGTGTTCCGCAAGTGCCAGATTGACCT
GGATATTGCTAACGGCAAATTTGTCGCCAAGGCGCGCTTCCTCGCCGAAGCGGGCTGGCGCGCGCTGCTTGGTAACAAAG
AGCGCGACGAAGAGAACGACGGTACGCCGCTGCCGGTGGTCGCCAAAGGCGATGAGCTATTGTGCGAGAAAGGTGAAGTG
GTGGAGCGACAGACCCAGCCGCCGCGCCACTTTACCGACGCGACGTTACTGTCGGCGATGACCGGTATTGCCCGCTTTGT
GCAGGATAAAGAACTGAAAAAGATCCTCCGCGCAACCGACGGTCTGGGGACGGAAGCGACCCGCGCCGGGATTATTGAGC
TGCTGTTTAAGCGCGGTTTCCTGAATAAAAAGGGGCGCTATATCCACTCATCGGATGCCGGTCGGGCGCTAATCCATTCT
CTGCCGGAAATGGCCGCGCGCCCGGATATGACCGCCCACTGGGAATCGGTATTGACGCAAATCAGCGAAAAACAGTGCCG
CTATCAGGACTTTATGCAGCCGCTGGTGGGGACGCTGTTCCAGCTTATCGATCAGGCGCGGAGCACGCCGGTGCGCCAGT
TCCGCGGGCTGGTCGCGCCAGGCGGAGCGAAAAAGTCGTTTAGTAAAGGGAAAGGCAAGCCGAAAGGGAAAAAGCCGGAG
GCGGACATCGCGCCGGAAAGTCCGCAATAA

Protein sequence :
MRLFIAEKPSLGRAIADVLPKPHRKGDGFIECGNGQVVTWCIGHLLEQAQPDVYDGRYARWNLLDLPIVPEKWQLQPKPS
VTKQLNVIKRLLGEAQEVVHAGDPDREGQLLVDEVLDYLQLAPEKRQQVQRCLINDLNPQAVERAINRLRANSEFVPLCV
SALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFDVKAHIVTPQDERFIATW
VPSEACEPYQDEEGRLLHRPLAEHVVKRIEGQPAIVTGYNDKRDSEPAPLPFSLSALQIEAAKRFGFSAQNVLDICQKLY
ETHKLITYPRSDSRYLPEEHFAGRHAVLNAISVHAPDLLPQPVMDPEIRNRCWDDKKVDAHHAIIPTARSSQVKLNDNEE
KVYNLIARQYLMQFCPDAVFRKCQIDLDIANGKFVAKARFLAEAGWRALLGNKERDEENDGTPLPVVAKGDELLCEKGEV
VERQTQPPRHFTDATLLSAMTGIARFVQDKELKKILRATDGLGTEATRAGIIELLFKRGFLNKKGRYIHSSDAGRALIHS
LPEMAARPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLFQLIDQARSTPVRQFRGLVAPGGAKKSFSKGKGKPKGKKPE
ADIAPESPQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 4e-110 41
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 3e-110 41
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 4e-110 41
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 1e-105 41
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 1e-102 41
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 2e-109 41