Gene Information

Name : EAE_20750 (EAE_20750)
Accession : YP_004594334.1
Strain : Enterobacter aerogenes KCTC 2190
Genome accession: NC_015663
Putative virulence/resistance : Virulence
Product : type VI secretion ATPase, ClpV1 family protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 4444576 - 4447206 bp
Length : 2631 bp
Strand : -
Note : COG0542 ATPases with chaperone activity, ATP-binding subunit

DNA sequence :
ATGGAAAACCCAGCCATCCTGTTACGCCGTTTAAACCCTTACTGCGCCCGCGCCCTGGAAGGCGCCGCTTCGCTGTGTCA
GGCCCGCGCGCATGCGCAAATCCTTCCAGAACACTGGCTGCTAAAACTACTGGAGCAGGGCGAGGGAGACCTGACCGTTT
TAGCGCGGCGTTATGAGTGGGATATGGACGCTATCTGGCAGGATCTGCTCTCTTTTCTGGAAACGCTTCCACGTTCGGTA
CACAGCCGGCCGCAGCTGTCCGGCAGCATCCAGAGCCTGATGCAGGAGGCGTGGCTGCGGGCTTCACTGGCGGGGGAGAC
CTCTCTACGCAGTGTTCATCTACTGATGGCGTTAGTCAGCAACCCAACGCGGGTGCGCTGTGACAGTCTGTGGCCGCTGT
TAACGTTGGGACAAGCGCAGCTTGAACACCTGCGACCATTATTAGATATGCAGTCTGATGAGCGCCCGGAATTACAGCCA
GATGAGCCTGGCCACGCTGGCGATGTGGAGTTTGTCGGCCGCCCCGTGGAATCGGCCGTGAAGTCCGCTGAGATGAACCC
AGCATTACAGAACGCGCTGGATAAATTTACCCTTGATATCACTGCTCGTGCCCGTGAAGGCAAAATCGACCCGGTTTTTG
GTCGCGATAACGAAATTCGTCAAATGGTGGATATCCTGTCGCGCAGAAGAAAAAACAACCCAATCCTGGTTGGCGAACCC
GGTGTCGGCAAAACCGCGCTGGTCGAAGGGCTGGCGTTGCGTATCGCGGAGGGCAACGTGCCGGACAGTCTGAAGCCGGT
TTCATTGCGTACGTTGGATCTCGGCTTACTGCAGGCCGGCGCAGGCGTCAAAGGGGAATTCGAACAGCGGCTTAAGAACA
TTATCGAAGCGGTACAGCAGTCGCCTGTCCCGGTGCTGCTGTTTATCGATGAAGCTCATACTATCATCGGCGCAGGCAAC
CAGGCCGGTGGCGCGGATGCCGCTAATTTGCTCAAACCGGCCCTGGCGCGCGGCGAACTGCGAACTATCGCCGCCACGAC
CTGGAGTGAGTATAAGCAGTACTTCGAGCGTGATGCCGCGCTGGAGCGCCGCTTCCAGATGGTCAAAGTCGACGAACCGG
ACGATGACACCGCCTGTCTGATGCTGCGCGGGCTGAAATCTCGCTATGCTCATCATCACGGGGTACATATCACCGATGAA
GCCATTCGCGCCGCCGTGACACTTTCCCGACGCTATCTCACCGGTCGCCAGTTGCCAGATAAAGCGGTGGACCTACTGGA
TACCGCATCGGCCCGCATTCGCATGGGAATCGATACGGTGCCGGAATTGTTGACGCGTATGAAAGCGCAAATCACGGCGC
TGGAAATGGAAAAACAGGCGCTACTGGAAGATGCCATGGTCGGTAGCGGTAGCGACGAAGCGCGGCTGGCGGCAATTGAG
CTGGAAGAATCGCGTATGATTTTACAGCTTGATGACCTGGAAACGCAGTACGGCCTGGAACTTAAGCTGACCGAGCAACT
GCTGAGCTGCCGAGCCGATCCTTCCCGCCGCAAGGAGATCGGTGAATTACAGAGCCAACTTGCCAGCGTCCAGAATAACC
ATCCGCTGCTGGGGCTGGATGTCGATTTACGTACCGTAGCAACGGTGATTGCCGACTGGACCGGGGTACCGCTCTCTCCA
TTGCTGAAGGACGAGCAGACGGAACTGCTGAGTCTCGAATCTAATCTGGATAAACGAGTGGTGGGGCAGGATATGGCGCT
AAACGCCATTGCCCAGAGACTGCGGGCGACCAAAACCGGGCTTGCACCGGATAACGGCCCGCAGGGCGTATTTCTGCTTG
TCGGTCCGAGCGGTACTGGAAAAACGGAAACCGCGCTGGCGCTGGCTGATGAACTGTTCGGTGGTGAAAGATCGCTGATT
ACCATCAATCTTTCCGAATATCAGGAGCCGCATACGGTGTCCCAACTGAAAGGATCGCCTCCCGGTTATGTCGGCTACGG
TCAGGGGGGGATTCTCACCGAAGCGGTACGCAAACGTCCGTACAGCGTGGTCCTGCTTGATGAAGTGGAAAAAGCGCATC
GCGATGTGATGAATTTATTCTACCAGGTGTTCGACCGTGGCTTTATGCGCGATGGCGAAGGACGCGAAATCGACTTCCGT
AATACGGTGATCCTGATGACCTCAAACCTCGGCAGCGATCGGCTGATGCAGATGCTGAAGGAACATCCGGAAGCGACAGA
ATCCGATTTACATGACCTGTTGCGGCCGGTGCTGCGAGAACATTTTCAACCAGCGCTGCTCGCGCGTTTCCAGACCATTA
TTTACCGGCCGCTCAGCCAGCCGGCGATGCGCAAAATTGTCAACATGAAACTCAACCAGGTCAGCCAGCGTTTGTATCGT
CATTACGGTATGACAACCGATATTGCCGAAGGCCTGTACGATGCGTTGACGGACGCCTGCCTGCTGCCGGATACCGGCGC
GCGTAACATTGACAGCCTGCTTAATCAACAAATTCTACCAGTGCTGAGTCAGCAACTGTTGAGCCATCTGGCGGCAGGGC
TGAAGCCGCAGAGCCTTTCTCTGGATGTCGATGAAGAAGGCGGCGTGGTCATGGAATTTAGCCACTCCTGA

Protein sequence :
MENPAILLRRLNPYCARALEGAASLCQARAHAQILPEHWLLKLLEQGEGDLTVLARRYEWDMDAIWQDLLSFLETLPRSV
HSRPQLSGSIQSLMQEAWLRASLAGETSLRSVHLLMALVSNPTRVRCDSLWPLLTLGQAQLEHLRPLLDMQSDERPELQP
DEPGHAGDVEFVGRPVESAVKSAEMNPALQNALDKFTLDITARAREGKIDPVFGRDNEIRQMVDILSRRRKNNPILVGEP
GVGKTALVEGLALRIAEGNVPDSLKPVSLRTLDLGLLQAGAGVKGEFEQRLKNIIEAVQQSPVPVLLFIDEAHTIIGAGN
QAGGADAANLLKPALARGELRTIAATTWSEYKQYFERDAALERRFQMVKVDEPDDDTACLMLRGLKSRYAHHHGVHITDE
AIRAAVTLSRRYLTGRQLPDKAVDLLDTASARIRMGIDTVPELLTRMKAQITALEMEKQALLEDAMVGSGSDEARLAAIE
LEESRMILQLDDLETQYGLELKLTEQLLSCRADPSRRKEIGELQSQLASVQNNHPLLGLDVDLRTVATVIADWTGVPLSP
LLKDEQTELLSLESNLDKRVVGQDMALNAIAQRLRATKTGLAPDNGPQGVFLLVGPSGTGKTETALALADELFGGERSLI
TINLSEYQEPHTVSQLKGSPPGYVGYGQGGILTEAVRKRPYSVVLLDEVEKAHRDVMNLFYQVFDRGFMRDGEGREIDFR
NTVILMTSNLGSDRLMQMLKEHPEATESDLHDLLRPVLREHFQPALLARFQTIIYRPLSQPAMRKIVNMKLNQVSQRLYR
HYGMTTDIAEGLYDALTDACLLPDTGARNIDSLLNQQILPVLSQQLLSHLAAGLKPQSLSLDVDEEGGVVMEFSHS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 1e-145 44
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 1e-131 43
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 8e-132 43
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 3e-110 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
EAE_20750 YP_004594334.1 type VI secretion ATPase, ClpV1 family protein VFG2076 Protein 5e-166 45
EAE_20750 YP_004594334.1 type VI secretion ATPase, ClpV1 family protein VFG2084 Protein 4e-135 43