Gene Information

Name : EAE_09990 (EAE_09990)
Accession : YP_004592193.1
Strain : Enterobacter aerogenes KCTC 2190
Genome accession: NC_015663
Putative virulence/resistance : Virulence
Product : DNA-binding transcriptional activator CusR
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 2124512 - 2125195 bp
Length : 684 bp
Strand : +
Note : COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

DNA sequence : 
GTGAAGATTTTGATTGTCGAAGATGAGAAGAAAACCGGGGAGTACCTGACCAAAGGGCTTACCGAAGCCGGATTCGTCGT
CGACCTGGCCGACAACGGCCTTAACGGTTATCACCTGGCGATGACCAGCGACTACGATCTGCTGATCCTCGACATCATGC
TGCCGGACGTCAACGGCTGGGATATCGTGCGCATGCTGCGCGCCGCCAATAAAGGGATGCCGATCCTGCTGCTCACCGCG
CTTGGCACTATCGAGCATCGGGTGAAGGGGCTGGAGCTGGGCGCCGACGACTATCTGGTGAAGCCCTTTGCTTTTGCGGA
ACTGCTGGCGCGGGTGCGCACTCTGCTGCGTCGCGGGGCGGCGGTAATAGTAGAAAGCCAGTTTCAGGCGGCCGATCTCA
GCGTTGATTTGGTCAGCCGCAAGGTGACGCGTGGCGCGACTCGTATCACCCTGACCAGCAAAGAGTTTACCCTGCTGGAG
TTCTTCTTGCGCCATCAGGGCGAGGTGCTACCCCGTTCGCTGATCGCGTCGCAGGTGTGGGATATGAATTTCGACAGCGA
CACTAACGCTATCGACGTGGCAGTGAAGCGGCTGCGCGCCAAAATCGATAACGACTTCGAGCCGAAGCTTATCCAGACCG
TGCGCGGCGTCGGCTATATGCTTGAGGTGCCGGATGGCCGCTAA

Protein sequence : 
MKILIVEDEKKTGEYLTKGLTEAGFVVDLADNGLNGYHLAMTSDYDLLILDIMLPDVNGWDIVRMLRAANKGMPILLLTA
LGTIEHRVKGLELGADDYLVKPFAFAELLARVRTLLRRGAAVIVESQFQAADLSVDLVSRKVTRGATRITLTSKEFTLLE
FFLRHQGEVLPRSLIASQVWDMNFDSDTNAIDVAVKRLRAKIDNDFEPKLIQTVRGVGYMLEVPDGR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 2e-55 52
copR AAC33719.1 regulatory protein CopR Not tested SPI-5 Protein 2e-55 52

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
EAE_09990 YP_004592193.1 DNA-binding transcriptional activator CusR BAC0111 Protein 1e-100 96
EAE_09990 YP_004592193.1 DNA-binding transcriptional activator CusR BAC0347 Protein 3e-87 83
EAE_09990 YP_004592193.1 DNA-binding transcriptional activator CusR BAC0083 Protein 2e-70 63
EAE_09990 YP_004592193.1 DNA-binding transcriptional activator CusR BAC0638 Protein 3e-63 62
EAE_09990 YP_004592193.1 DNA-binding transcriptional activator CusR BAC0308 Protein 5e-63 59
EAE_09990 YP_004592193.1 DNA-binding transcriptional activator CusR BAC0197 Protein 4e-63 59
EAE_09990 YP_004592193.1 DNA-binding transcriptional activator CusR BAC0125 Protein 5e-65 56
EAE_09990 YP_004592193.1 DNA-binding transcriptional activator CusR AE000516.2.gene3505. Protein 4e-27 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
EAE_09990 YP_004592193.1 DNA-binding transcriptional activator CusR VFG0596 Protein 8e-56 52
EAE_09990 YP_004592193.1 DNA-binding transcriptional activator CusR VFG1390 Protein 9e-45 45