Gene Information

Name : EAE_09085 (EAE_09085)
Accession : YP_004592016.1
Strain : Enterobacter aerogenes KCTC 2190
Genome accession: NC_015663
Putative virulence/resistance : Unknown
Product : prothage integrase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0582
EC number : -
Position : 1922832 - 1924088 bp
Length : 1257 bp
Strand : -
Note : COG0582 Integrase

DNA sequence :
ATGGCGCTCACTGACGCTAAAATCCGTGCAGCTAAACCGGATGAAAAACCTTATAAACTTGCCGACAGCGGCAACATGTT
TTTGCTCGTTCACCCTAACGGCTCGCGCTACTGGCGACTGCGTTACCGGTTTCTGGGCAAAGAAAAAACGCTCGCTCTGG
GCGTCTACCCAGAAGTCTCGTTATCAGAAGCAAGGGAAAAACGCGATACGGCGAGGAAGCTGATAGCTGAGGGAACTGAC
CCGTGCGAACATAAACGGATCAAAAAGTCTGTGCCTGAAACAGCTCAGACATTCGAAGGCATCGCAAGGCAGTGGCATAA
GAGCAACAAAAAATGGTCAGATTCACACAGTGAGAAAATACTGAAAAGCCTCGAAACTCATGTGTTTCCCTTTATTGGCT
CACGTGACATTACCACCCTCAGAACTCCCGATTTACTTGTTCCAGTAAAGGCAGCCGAAGCCAAAGAGATCTATGAGATT
GCAGCGCGCCTTCAGCAGCGTATCACTGCAATCATGCGCTATGCTGCCCAGTCAGGCATTATCACCTATAACCCTGCCGT
TGATATGGCTGGCGCTTTAACGACGGTGAAACGCCAGCACCGCCCTGCCCTCGCCTTAAATCGCATTTCAGAGCTACTTG
AACGACTGGATGCATACAGAGGGCAACCTCTCACCCGACTGGCAACTAAACTTACCCTACTCATCTTCATCCGTTCCAGT
GAACTACGCTTTGCCAGGTGGTCTGAGATCGACTTCAAGAAAGCCATGTGGACCATTCCTCCTGAGCGGAAACCTATTGA
GGGGGTAAAGTATTCCCATCGTGGCTCAAAAATGCGTACAGAGCATCTGGTACCACTCTCAACTCAGGCACTGGATATTC
TGCAGCAGATCCACACCATCAGCGGTGAATATGAGTTGATTTTCACTGGCGACCATAATCCCTGGAAACCCATGAGTGAA
AATACGGTGAATAACGCATTACGCCTGATGGGCTACGATACAAAGATCGATGTCTGTGGTCACGGCTTCCGGGCAATGGC
CTGTAGTTCGTTGATTGAGTCAGGATTATGGTCGAGAGATGCAGTGGAGCGCCAGATGAGCCATCAGGAACGAAATGGCG
TACGTGCGGCTTATATCCATAAAGCGGAGTTTCTGGATGAACGCAGACTGATGCTGCAGTGGTGGGCTGATTTTCTGGAT
GCAAATGAGGAAAAAACAGTGAGCCCGTTTGACTTCGCAAAACTCCATTCTCGATAG

Protein sequence :
MALTDAKIRAAKPDEKPYKLADSGNMFLLVHPNGSRYWRLRYRFLGKEKTLALGVYPEVSLSEAREKRDTARKLIAEGTD
PCEHKRIKKSVPETAQTFEGIARQWHKSNKKWSDSHSEKILKSLETHVFPFIGSRDITTLRTPDLLVPVKAAEAKEIYEI
AARLQQRITAIMRYAAQSGIITYNPAVDMAGALTTVKRQHRPALALNRISELLERLDAYRGQPLTRLATKLTLLIFIRSS
ELRFARWSEIDFKKAMWTIPPERKPIEGVKYSHRGSKMRTEHLVPLSTQALDILQQIHTISGEYELIFTGDHNPWKPMSE
NTVNNALRLMGYDTKIDVCGHGFRAMACSSLIESGLWSRDAVERQMSHQERNGVRAAYIHKAEFLDERRLMLQWWADFLD
ANEEKTVSPFDFAKLHSR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ECO111_3718 YP_003236059.1 putative integrase Not tested LEE Protein 2e-157 78
ORF_1 AAZ04412.1 phage integrase Not tested PAI I APEC-O1 Protein 1e-159 78
c5216 NP_757064.1 prophage P4 integrase Not tested PAI II CFT073 Protein 6e-159 78
APECO1_3534 YP_854214.1 P4-like integrase Not tested PAI I APEC-O1 Protein 2e-159 78
S4822 NP_838459.1 P4-type integrase Not tested SHI-1 Protein 7e-160 78
SF2964 NP_708738.1 P4-type integrase Not tested SHI-1 Protein 7e-160 78
int AAK00456.1 Int Not tested SHI-1 Protein 3e-150 78
int AAT48697.1 CP4-like integrase Not tested PAI I 4787 Protein 8e-159 78
c3556 NP_755431.1 prophage P4 integrase Not tested PAI I CFT073 Protein 5e-159 78
int AAL51003.1 CP4-like integrase Not tested LEE Protein 8e-159 78
intP4 CAE85151.1 CP4 integrase protein Not tested PAI V 536 Protein 4e-159 78
int AAK16198.1 Int Not tested PAI-I AL862 Protein 2e-159 78
int CAC81896.1 integrase Not tested LEE II Protein 2e-148 78
int ADD91747.1 P4 integrase Not tested PAI-I AL862 Protein 2e-159 78
int-phe AAL57571.1 CP4-like integrase Not tested LEE Protein 3e-158 77
ECO103_3550 YP_003223418.1 integrase Not tested LEE Protein 4e-158 77
int AAL51028.1 CP4-like integrase Not tested LEE Protein 3e-158 77
ECO26_5300 YP_003232178.1 integrase Not tested LEE Protein 4e-158 77
int-phe AAL60261.1 Int-phe Not tested LEE Protein 3e-158 77
ECUMN_3322 YP_002414004.1 integrase Not tested Not named Protein 1e-156 77
Z4313 NP_289539.1 pathogenicity island integrase Not tested OI-122 Protein 2e-157 77
intB CAD42017.1 bacteriophage P4 integrase Not tested PAI II 536 Protein 2e-133 68
SESS1296_03598 AFO66301.1 bacteriophage integrase Not tested SESS LEE Protein 8e-123 60
SESS1635_03816 AFO66367.1 bacteriophage integrase Not tested SESS LEE Protein 8e-123 60
STY4821 NP_458899.1 integrase Not tested SPI-10 Protein 2e-114 56
int CAB59974.1 integrase Not tested HPI Protein 3e-108 55
APECO1_1051 YP_853069.1 phage integrase Not tested PAI IV APEC-O1 Protein 1e-75 54
int NP_458759.1 bacteriophage integrase Not tested SPI-7 Protein 9e-111 54
int NP_807963.1 bacteriophage integrase Not tested SPI-7 Protein 9e-111 54
int2 NP_993013.1 integrase Not tested HPI Protein 8e-107 54
int CAA08754.1 integrase Not tested HPI Protein 2e-107 54
int CAA21384.1 - Not tested HPI Protein 8e-107 54
int YP_002346908.1 integrase Not tested HPI Protein 8e-107 54
y2393 NP_669700.1 prophage integrase Not tested HPI Protein 8e-107 54
unnamed AAD17660.1 unknown Not tested HPI Protein 3e-104 53
intB AAD37509.1 P4-like integrase Not tested PAI IV 536 Protein 2e-87 53
unnamed ABR13507.1 phage integrase Not tested PAGI-6 Protein 7e-107 52
unnamed AFX83955.1 integrase Not tested SE-PAI Protein 1e-76 43
int AAD44730.1 Int Not tested SHI-2 Protein 2e-82 43
aec33 AAW51716.1 Int Not tested AGI-3 Protein 4e-83 43
int CAC39282.1 integrase Not tested LPA Protein 4e-83 43
ESA_03025 YP_001439090.1 hypothetical protein Not tested Not named Protein 6e-76 42
int AAC31482.1 CP4-like integrase Not tested LEE Protein 1e-81 41
int ACU09430.1 integrase Not tested LEE Protein 1e-81 41
intL NP_290239.1 integrase for prophage 933L and the LEE pathogenicity island Not tested LEE Protein 2e-81 41
ECs4534 NP_312561.1 integrase Not tested LEE Protein 2e-81 41
int AAD54663.1 Sai integrase Not tested SHI-2 Protein 5e-81 41
S4835 NP_839238.1 integrase Not tested SHI-2 Protein 6e-81 41
SF3698 NP_709437.1 integrase Not tested SHI-2 Protein 6e-81 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
EAE_09085 YP_004592016.1 prothage integrase VFG0626 Protein 3e-160 78
EAE_09085 YP_004592016.1 prothage integrase VFG1693 Protein 2e-159 78
EAE_09085 YP_004592016.1 prothage integrase VFG1536 Protein 1e-133 68
EAE_09085 YP_004592016.1 prothage integrase VFG0783 Protein 7e-82 41
EAE_09085 YP_004592016.1 prothage integrase VFG0598 Protein 3e-81 41