Gene Information

Name : guaA (EAE_00660)
Accession : YP_004590349.1
Strain : Enterobacter aerogenes KCTC 2190
Genome accession: NC_015663
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 137431 - 139008 bp
Length : 1578 bp
Strand : -
Note : COG0518 GMP synthase - Glutamine amidotransferase domain

DNA sequence :
ATGACGGATAACATTCATAAACATCGCATTCTTATCCTGGACTTCGGTTCTCAGTACACCCAGCTGGTTGCGCGTCGCGT
ACGTGAATTAGGGGTCTATTGCGAGCTCTGGGCTTGGGACGTGACCGAAGCTCAAATCCGCGAGTTCAACCCGAACGGCA
TTATTCTTTCCGGCGGCCCGGAAAGCACCACCGAAGACAACAGCCCGCGTGCGCCGCAGTACGTCTTCGAAGCCGGCGTA
CCGGTATTCGGCGTATGCTATGGCATGCAGACCATGGCCATGCAGCTGGGCGGCCACGTTGAAGCTTCCAACGAGCGCGA
GTTCGGTTACGCGCAGGTGGAAGTGCAGACCGACAGCGCGCTGATCAAGGGCATCGAAGATGCGCTGAGCGCTGACGGTA
AGCCGCTGCTGGACGTGTGGATGAGCCATGGTGATAAAGTCACCGCTATCCCTTCCGACTTTGTGACCGTCGCCAGCACT
GAAAGCTGCCCGTTCGCCATCATGGCGAATGAAGAAAAACGCTTCTACGGCGTACAGTTCCACCCGGAAGTCACCCACAC
CCGTCAGGGGCTGCGTATGCTGGAGCGCTTCGTGCGCGACATCTGCCAGTGTGAAGCGCTGTGGACGCCGGCGAAGATCA
TCGACGACGCGGTTGAGCGTATTCGTCAGCAGGTGGGTGAAGATAAAGTCATCCTCGGCCTGTCCGGCGGCGTTGACTCT
TCCGTTACCGCGATGCTGCTGCACCGCGCCATCGGCAAAAATCTGACCTGCGTATTCGTGGATAACGGCCTGCTGCGCCT
GAACGAAGCCGAGCAGGTTATGGATATGTTCGGCGACCGTTTCGGCCTGAACATCGTACACGTTGCGGCGGAAGATCGCT
TCCTGACCGCGCTGAAGGGCGAAAACGATCCGGAAGCGAAGCGTAAAATCATTGGCCGCGTCTTCGTTGAAGTGTTTGAC
GAAGAAGCGCTGAAGCTGGAAGACGTGAAATGGCTGGCGCAGGGCACTATCTACCCTGACGTGATCGAATCCGCTGCTTC
CGCGACCGGTAAAGCGCACGTCATCAAGTCTCACCACAACGTGGGCGGTCTGCCGAAAGAAATGAAGATGGGCCTCGTTG
AGCCGCTGAAAGAGCTGTTCAAAGACGAAGTGCGTAAGATTGGTCTGGAGCTGGGCCTGCCGTACGACATGCTGTTCCGC
CACCCGTTCCCGGGGCCGGGCCTCGGCGTTCGCGTACTTGGCGAAGTGAAGAAAGAGTACTGCGACCTGCTGCGTCGCGC
GGACGCTATCTTCATTGAAGAACTGCGCAAAGCCGACCTGTATGACAAAGTAAGCCAGGCATTCACCGTGTTCCTGCCGG
TTCGCTCCGTCGGCGTGATGGGCGATGGTCGTAAGTACGACTGGGTCGTCTCCCTGCGTGCGGTAGAAACCATCGACTTT
ATGACCGCGCACTGGGCGCACCTGCCGTATGATTTCCTCGGCCGTGTTTCCAACCGCATCATCAACGAAGTTAACGGTAT
TTCCCGCGTGGTGTACGACATCAGCGGTAAGCCGCCAGCGACTATTGAGTGGGAATAA

Protein sequence :
MTDNIHKHRILILDFGSQYTQLVARRVRELGVYCELWAWDVTEAQIREFNPNGIILSGGPESTTEDNSPRAPQYVFEAGV
PVFGVCYGMQTMAMQLGGHVEASNEREFGYAQVEVQTDSALIKGIEDALSADGKPLLDVWMSHGDKVTAIPSDFVTVAST
ESCPFAIMANEEKRFYGVQFHPEVTHTRQGLRMLERFVRDICQCEALWTPAKIIDDAVERIRQQVGEDKVILGLSGGVDS
SVTAMLLHRAIGKNLTCVFVDNGLLRLNEAEQVMDMFGDRFGLNIVHVAAEDRFLTALKGENDPEAKRKIIGRVFVEVFD
EEALKLEDVKWLAQGTIYPDVIESAASATGKAHVIKSHHNVGGLPKEMKMGLVEPLKELFKDEVRKIGLELGLPYDMLFR
HPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELRKADLYDKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDF
MTAHWAHLPYDFLGRVSNRIINEVNGISRVVYDISGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-129 52
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-129 52
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-129 52
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-110 48