Gene Information

Name : Geoth_0268 (Geoth_0268)
Accession : YP_004586397.1
Strain : Geobacillus thermoglucosidasius C56-YS93
Genome accession: NC_015660
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 274717 - 276237 bp
Length : 1521 bp
Strand : -
Note : PFAM: Aldehyde dehydrogenase; KEGG: gmc:GY4MC1_0254 aldehyde dehydrogenase

DNA sequence : 
ATGATTTACGCTCAACCTGGGCAGCCTGGTTCGCTCATCACTTTCAAAAAACGCTATGAAAATTTCATTGGCGGCAAATG
GGTTCCGCCGGTCGATGGCGAGTATTTTGAAAACATCTCTCCAGTCACCGGGAAACCTTATTGTGAAGTGCCGCGTTCCA
AAGCAGCAGACATTGAGTTAGCGTTAGACGCTGCCCATGCCGCGAAAGACGCGTGGGGCCGCACTTCCCCTGCCGAACGC
GCGCGAATCCTCAACAAAATCGCCGACCGCATCGAAGAAAACTTGGAAATGCTCGCTGTTGCGGAAACATGGGAAAACGG
CAAGCCGATTCGCGAAACGCTGAATGCGGACATTCCGCTTGCCATCGATCATTTCCGCTATTTTGCCGGCTGCATCCGCG
CAGAAGAAGGGACGTTAGCGGAAATCGACAATGATACAGTCGCCTATCACTTTAAAGAACCGCTTGGGGTTGTCGGGCAA
ATCATCCCATGGAACTTCCCGCTTTTAATGGCAACTTGGAAGCTCGCGCCAGCATTAGCCGCGGGAAACTGCGTTGTCCT
GAAACCTGCAGAACAAACGCCAACTTCGATCCTCGTGCTTATGGAACTCATTGAAGATTTGCTTCCTCCAGGTGTTGTCA
ACATCGTCAACGGATTCGGCTTGGAAGCCGGAAAACCGCTCGCTTCAAGCAACCGCATTGCGAAAATTGCATTCACCGGT
GAAACGACAACAGGGCGTTTAATTATGCAATACGCATCGCAAAACATTATCCCAGTAACATTAGAGCTTGGCGGAAAATC
GCCGAACATTTTCTTCGAAGATGTTGCGGCAAAAGATGATGAATTTTTCGATAAAGCCATTGAAGGCTTTACGCTGTTCG
CGTTAAACCAAGGTGAAATATGTACGTGCCCTTCCCGCGCTCTCATTCAAGAATCGATTTACGACCAATTTATAGAGCGT
GCGTTAGAGCGCGTTAAACAAATAAAACAAGGCAACCCGCTCGACACGGAAACGATGATCGGCGCCCAAGCATCTTCGGA
ACAATTGGAAAAAATATTATCGTACATTGATATCGGCAAGCAAGAAGGTGCCGAATTGCTTATCGGCGGAGAACGCAACT
TCTTAGAAGGAGACTTAAGAGACGGCTATTATGTGAAACCGACGGTTTTCAAAGGCCATAATAAAATGCGCATTTTCCAA
GAAGAAATTTTCGGGCCGGTTGTCTCCGTCACGACGTTTAAAGATGTCAACGAGGCGTTGGAGATCGCCAACGAAACATT
GTACGGTTTAGGCGCCGGCGTCTGGACACGCGACATTAACACCGCTTATCGCGTCGGACGCGGCATCCAGGCAGGACGCG
TCTGGACAAACTGCTACCACATCTATCCTGCGCACGCGGCATTCGGGGGCTATAAGTTATCCGGATTCGGCCGTGAAACG
CATAAAATGATGCTTGAACATTATCAACAAACGAAAAACTTGCTTGTCAGCTATTCGCCGAAAAAACTTGGGCTCTTCTA
A

Protein sequence : 
MIYAQPGQPGSLITFKKRYENFIGGKWVPPVDGEYFENISPVTGKPYCEVPRSKAADIELALDAAHAAKDAWGRTSPAER
ARILNKIADRIEENLEMLAVAETWENGKPIRETLNADIPLAIDHFRYFAGCIRAEEGTLAEIDNDTVAYHFKEPLGVVGQ
IIPWNFPLLMATWKLAPALAAGNCVVLKPAEQTPTSILVLMELIEDLLPPGVVNIVNGFGLEAGKPLASSNRIAKIAFTG
ETTTGRLIMQYASQNIIPVTLELGGKSPNIFFEDVAAKDDEFFDKAIEGFTLFALNQGEICTCPSRALIQESIYDQFIER
ALERVKQIKQGNPLDTETMIGAQASSEQLEKILSYIDIGKQEGAELLIGGERNFLEGDLRDGYYVKPTVFKGHNKMRIFQ
EEIFGPVVSVTTFKDVNEALEIANETLYGLGAGVWTRDINTAYRVGRGIQAGRVWTNCYHIYPAHAAFGGYKLSGFGRET
HKMMLEHYQQTKNLLVSYSPKKLGLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-151 66
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 1e-159 65
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 1e-159 65
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 1e-159 65
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 9e-159 65
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 1e-70 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Geoth_0268 YP_004586397.1 aldehyde dehydrogenase VFG0082 Protein 1e-151 66