Gene Information

Name : Geoth_2305 (Geoth_2305)
Accession : YP_004588312.1
Strain : Geobacillus thermoglucosidasius C56-YS93
Genome accession: NC_015660
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : 3.5.1.5
Position : 2229831 - 2231543 bp
Length : 1713 bp
Strand : -
Note : PFAM: Amidohydrolase 1; Urease alpha-subunit, N-terminal; TIGRFAM: Urease, alpha subunit; HAMAP: Urease subunit alpha; KEGG: gmc:GY4MC1_2219 urease, alpha subunit

DNA sequence :
ATGAGTTTTTCCATGTCACGAAAACAATATGCGGACATGTTTGGACCGACAACAGGAGATTGTGTTCGTTTAGCGGATAC
CGATTTATGGATTGAGATGGAACAGGACTTTACCGTCTATGGCGATGAAGTAAAATTTGGCGGCGGAAAAGTCATTCGTG
ATGGAATGGGGCAACACCCGCTTGCCACGCGTGCGGAATCGGTGGATTTAGTGCTGACGAACGCGATGATTGTCGACTAT
ACCGGAATTTATAAAGCCGATATCGGGATTAAAGACGGGAAAATTGCCGCCATTGGGAAAGCGGGCAATCCGTTGTTAAT
GGACGGAGTCAATATCATCATCGGAGCGGCGACAGAAGTGATTGCGGCGGAGGGGAAAATTGTTACCGCAGGAGGAATTG
ACGCCCATATTCACTTTATTTGTCCGCAACAAATCGAAACGGCTTTGTCATCGGGGATTACGACGATGATCGGCGGGGGA
ACCGGGCCGGCGACGGGAACCAATGCGACGACATGCACCCCTGGGGAATGGAACATCTATCGCATGTTGGAAGCGGCCGA
AGCGTTTCCGATGAATCTTGGATTTTTAGGGAAAGGCAACGCATCGGCGAAAGAGCCGTTAGCGGAGCAAATTCGCGCAG
GAGCCATTGGCTTAAAGCTTCATGAAGATTGGGGGACAACAGCGGCAGCCATTGATGCCAGTTTGCAGGTTGCGGACGAA
TATGATGTGCAAGTGGCGATTCATACCGATACGCTGAATGAAGGGGGATTTGTCGAAGATACATTACGGGCGATTAACGG
GCGCGTCATTCACACCTATCATACGGAAGGAGCGGGCGGAGGACATGCGCCAGATATTATGAAAGTAGCGAGTTTTCCAA
ATATATTGCCTTCTTCTACCAATCCAACGCGGCCTTATACAAAAAATACGTTAGCGGAGCATTTAGACATGTTGATGGTT
TGCCATCATTTAGACCCGTCTGTTCCGGAAGATATTGCCTTTGCCGACTCGCGCATTCGCAAAGAAACGATTGCGGCGGA
AGATATTCTCCATGATTTCGGTGCTTTTAGCATGATCAGTTCTGATTCGCAAGCAATGGGGCGTGTCGGGGAAGTAATTT
TGCGCACATGGCAAACAGCGGATAAGATGAAAAAGCAATTTGGGAAATTGCCAGAAGACAAAGGAAGAAAAGGAGATAAT
TTTCGCGTAAAGCGTTATATTGCCAAATATACGATAAATCCGGCGCTTACCCACGGGATTGCGAAGCATGTCGGATCGGT
TGAAGTGGGGAAATTGGCCGATTTAGTCGTTTGGCATCCTGCGTTTTTCGGCGTTAAACCAGAACTTGTGCTGAAAGGGG
GAATGATTGCCTATAGCGTCATGGGAGATCCCAATGCCAGCATTCCGACTCCGCAGCCAGCCATGTATCGGCCGATGTTT
GCAAGCTATGGAAAGGCTTTATATAACACTTCGATTACATTTGTATCAAAAGCAGCTTTTGAGCGCGGAATCCCGCAGAA
ATTGAAGTTGCAAAAAATCATTCAACCAGTAGAGCACATTCGCCGTTTGTCGAAAAAGGATATGGTGTTCAACAATGCAA
TGCCAAAGATTGATGTCGATCCGCAAACGTATGAAGTAAAAGTGGACGGAACCATTATTACGTGTGAACCAGCCGAAGTA
ATCCCGATGGCGCAACGATATTTTTTATTTTGA

Protein sequence :
MSFSMSRKQYADMFGPTTGDCVRLADTDLWIEMEQDFTVYGDEVKFGGGKVIRDGMGQHPLATRAESVDLVLTNAMIVDY
TGIYKADIGIKDGKIAAIGKAGNPLLMDGVNIIIGAATEVIAAEGKIVTAGGIDAHIHFICPQQIETALSSGITTMIGGG
TGPATGTNATTCTPGEWNIYRMLEAAEAFPMNLGFLGKGNASAKEPLAEQIRAGAIGLKLHEDWGTTAAAIDASLQVADE
YDVQVAIHTDTLNEGGFVEDTLRAINGRVIHTYHTEGAGGGHAPDIMKVASFPNILPSSTNPTRPYTKNTLAEHLDMLMV
CHHLDPSVPEDIAFADSRIRKETIAAEDILHDFGAFSMISSDSQAMGRVGEVILRTWQTADKMKKQFGKLPEDKGRKGDN
FRVKRYIAKYTINPALTHGIAKHVGSVEVGKLADLVVWHPAFFGVKPELVLKGGMIAYSVMGDPNASIPTPQPAMYRPMF
ASYGKALYNTSITFVSKAAFERGIPQKLKLQKIIQPVEHIRRLSKKDMVFNNAMPKIDVDPQTYEVKVDGTIITCEPAEV
IPMAQRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 3e-168 68
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 3e-168 68
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 6e-164 65
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-165 65
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 1e-165 65
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-165 65

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Geoth_2305 YP_004588312.1 urease subunit alpha VFG0270 Protein 1e-160 67