Gene Information

Name : Geoth_1804 (Geoth_1804)
Accession : YP_004587851.1
Strain : Geobacillus thermoglucosidasius C56-YS93
Genome accession: NC_015660
Putative virulence/resistance : Resistance
Product : heavy metal translocating P-type ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : 3.6.3.3
Position : 1719357 - 1721474 bp
Length : 2118 bp
Strand : +
Note : TIGRFAM: ATPase, P-type, heavy metal translocating; ATPase, P-type, heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating; ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; KEGG: gmc:GY4MC1_1725 cadmium-translocating P-type ATPase; PFAM: ATPase, P-type, ATPase-a

DNA sequence :
ATGGAAAATAAACAAGTGTACCGTCTTCAAGGACTTTCATGCGCCAATTGCGCAGCAACGTTTGAAAAAAATGTGAAGGC
GATTGCGACGGTGAAAGATGCCAAAGTCAATTTCGGCGCGGCGACACTGACGGTCATCGGCGAAGCGTCGATCGAAGAAC
TTGAAAAAGCGGGAGCGTTTGACAGGATTGCCGTTATTCCGGAAACGGAGCGAAAAGACCAAAAGGCAGAACCGTTTTGG
AAAAAGAAAACAAACGTCATCGCGCTGATATCGGCTTTCTTTCTTCTTGCCGGCTACGTGTCTGCTTATGCGATGGGGGA
ACGGCATATTGCCACCATTTTGTTATTTGCGGCAAGCATTATCATTGGCGGTTATTCTTTATTAAAAACAGGACTTGCCA
ATCTTGTGCGGCTTCAATTTGATATGAACACTTTAATGACGATCGCTGTCATTGGGGCGGCGTGCATCGGAGAATGGAAA
GAAGGAGCGGTTGTCGTCTTCCTGTTTGCGATCAGTGAAGCGCTCGAGCGCTATTCCATGGATACGGCGCGCCGTTCGCT
TCAGCGGCTCATGGATATCGCTCCGAAAAAAGCGACCGTGCTTCGGGATGGCAAAGAGTATGAAGTGGATGTGGAAGATG
TCGTTGTCGGCGATACGATTCTTGTGAAGCCGGGGCAAAAAATCGCGATGGACGGCGTTGTGCTTCGCGGGGAGTCGTTG
GTTAACGAAGCGGCGATTACCGGCGAATCGATGCCAGTCGCCAAAACCGTCGGCGATGAAGTATATGCGGGAACGATGAA
CGAAGATGGCGCCCTTGAAGTACGGGTGACAAAGCGCGTAGAAGACACAACGATTGCGAAAATCATTCATCTTGTCGAAG
AAGCGCAGGCCGAGCGGGCGCCAACCCAGCAGTTTGTCGACCGCTTTGCCCGCTACTATACACCAACGATTATGCTGATC
GCCTTGTTTGTTGCCACTGTGCCGCCGCTGTGGCTTGGCGGAGAATGGCTGACATGGGTTTACCGCGGCTTAACGGTGCT
TGTTGTCGGCTGTCCGTGCGCGCTTGTCATAAGCACGCCGGTAGCGATCGTAACTGCCATTGGACAAGCGGCGCGGCAAG
GGGTGCTGATTAAAGGCGGGGTGTATTTAGAAGAAATCGGAAAGATATCGGCAATTGCATTTGATAAAACAGGAACGTTA
ACGACAGGGATACCGGAAGTGGCTGATATTTATTCATTTAGCGACTTGGATGAAGAGGAATTGTTAAAAATCGCCGCAGC
CATTGAGAAACAGTCGGAGCATCCGCTTGCTTCCGCCATTTTGCGCAAGGCAGAGGCATTGCAAATATCATCCGACGATT
TGCAAGTAAGCGAGTTTCGCGCTATGGCTGGCAAAGGTGCGGCAGCCCGTGTGAATGGAGTTATGTATTATATTGGGAAA
CCGTCTTTGTTCTCTGAGGCTATACATGAAGACATTCGTGCGCAAATTGCCCGCGAACAAACACAAGGAAAAACAGTCAT
GTTGCTTGGAAATGAAACAAAAGTGCTTGGCATGATTGCCGTTTCCGATCAACTGCGTGAAAATGCCGCTTCTGTGCTAG
AAACATTACGCAACTTAGGAATCTCGCAAACTATCATGTTAACCGGCGATCACGAAACGACCGCGCGGGCCATTGCCTCT
TCCCTTCCGCTTACCGATATTCGCGCTGAATTGCTTCCAGAAGAAAAATGGACGGCGATTCAAACGCTGCAGCGTCAATC
AGGACGCATCGCGATGGTCGGCGATGGTGTCAACGACGCTCCCGCGCTTGCTGCGGCAGATGTTGGCATTGCGATGGGGG
ATATTGGCACCGATGTGGCGTTAGAAACAGCGGACGTTGTCTTAATTGGCGATGATCTTGAAAAGCTTCCGTATGTCATC
CGGTTAGGACGAAAAGCAATGCGCATTATTCAAGAGAACATCGCGGTTGCCTTGTTGTTAAAAGTGTTGGCGCTCGTTCT
CATTGTTCCTGGCTGGCTTACATTGTGGATGGCCATTTTTGCGGATATGGGGGCGACGCTGCTCGTATTGCTCAATTCGC
TGCGGCTGCTCCGCCTTGATGGGATCAGCAAAAAATGA

Protein sequence :
MENKQVYRLQGLSCANCAATFEKNVKAIATVKDAKVNFGAATLTVIGEASIEELEKAGAFDRIAVIPETERKDQKAEPFW
KKKTNVIALISAFFLLAGYVSAYAMGERHIATILLFAASIIIGGYSLLKTGLANLVRLQFDMNTLMTIAVIGAACIGEWK
EGAVVVFLFAISEALERYSMDTARRSLQRLMDIAPKKATVLRDGKEYEVDVEDVVVGDTILVKPGQKIAMDGVVLRGESL
VNEAAITGESMPVAKTVGDEVYAGTMNEDGALEVRVTKRVEDTTIAKIIHLVEEAQAERAPTQQFVDRFARYYTPTIMLI
ALFVATVPPLWLGGEWLTWVYRGLTVLVVGCPCALVISTPVAIVTAIGQAARQGVLIKGGVYLEEIGKISAIAFDKTGTL
TTGIPEVADIYSFSDLDEEELLKIAAAIEKQSEHPLASAILRKAEALQISSDDLQVSEFRAMAGKGAAARVNGVMYYIGK
PSLFSEAIHEDIRAQIAREQTQGKTVMLLGNETKVLGMIAVSDQLRENAASVLETLRNLGISQTIMLTGDHETTARAIAS
SLPLTDIRAELLPEEKWTAIQTLQRQSGRIAMVGDGVNDAPALAAADVGIAMGDIGTDVALETADVVLIGDDLEKLPYVI
RLGRKAMRIIQENIAVALLLKVLALVLIVPGWLTLWMAIFADMGATLLVLLNSLRLLRLDGISKK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 0.0 58
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 0.0 58
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 0.0 56

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Geoth_1804 YP_004587851.1 heavy metal translocating P-type ATPase BAC0298 Protein 1e-98 46
Geoth_1804 YP_004587851.1 heavy metal translocating P-type ATPase BAC0092 Protein 4e-92 44