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Name : Geoth_1583 (Geoth_1583) Accession : YP_004587642.1 Strain : Geobacillus thermoglucosidasius C56-YS93 Genome accession: NC_015660 Putative virulence/resistance : Virulence Product : betaine aldehyde dehydrogenase Function : - COG functional category : C : Energy production and conversion COG ID : COG1012 EC number : 1.2.1.8 Position : 1511158 - 1512675 bp Length : 1518 bp Strand : + Note : KEGG: gmc:GY4MC1_1491 aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase DNA sequence : ATGGCGACCGTGAAAGAACAAAAAATGGAGAAGCTTGAAACAAAACGTGAAATGTATCATCTGATTATTAACGGGGAACG TGTCGAAAGCGCTTCCGGGGAAACGTTTACGACATACAACCCGGCAACAGGGGAGCCGGTTGCGAAAGTAGCGAAAGGAA CGAAAGAAGATGCGGAGCGTGCTATTCAAGCGGCGCGTCAAGCTTTTGATCATGGCAAATGGCGCCATTTTCCTGTCAAC AAACGGGCGCGTATTTTAAACAAAATTGCTTCTATTATGCGTTCCCGTTTTCATGAGTTAGTAGAATTAGAGATTTTAGA TACAGGGAAAGCACTTTCCGCCGCACAAGGGCAAGTGATGCAGGCGATTGAAGATTTTGAATTTTACGCCAGTGCCATTA TCAGCCATCGCGGCACGGTCAACAATATGCCAGGTGCGTTTCATAATTTTACCGAAAAAGAGCCTGTCGGGGTATGTGCG CAAATTATCCCATGGAATTATCCATTGATGATGGCAGCGTGGAAAATTGCCCCAGCCATTGCAGCAGGGTGTTCCGTTGT TGTCAAGCCGGCTTCATTAACACCGCTGACATGTATCGTACTTGCAGAAATTTGTCATGAAGCTGGCGTCCCGGAAGGTG TCGTCAACGTAGTGACCGGGTCTGGCTCTGAAGTCGGGAATTATTTAGTTGAGCATCCGCTTGTTGATAAAGTTGCCTTT ACTGGTTCGACTCCAGTTGGAAAAAATATTATGGAAAAAGCGTCGAAAACGTTAAAACGGGTAACATTAGAACTCGGCGG CAAATCGCCGAACATCATCTTCGAGGATGCAGACATTGATGCCGCTGTTAACGGTTCATTATTCGGAATTTTCTATAATA CCGGACAATCTTGTGAAGCGCGTTCCCGTTTATACGTACATGAAAGTATTTACGATCAATTCATCGAAAAATTTGTTGAA AAAACGAAAAAATTGAAGCTTGGCAATCCGTTTGAGCAAGATACCCATGTTGGTGCCATCATTAGCCGCGAACAACTAGA AGTTATTGACGGCTATGTGAAATCTGCCATCGAAGAGGGAGCTACGATTGTCACTGGCGGGAGAAAAGCGAAAGTGGAAG GGTTTGAAAACGGTTTTTGGTACGAACCAACCATTATTACGGATGTCAATCATCAAATGAAAGTCGTTAAAGAAGAAATT TTCGGCCCGGTCGTCGTTGTAATGAAATTTAATGATGAAAATGAGGTCATTAAATTGGCTAATGACAGTGAATATGGCTT GGGATCGGCCATCTGGACAAAAGATCATGCACGTGCGATTCGTGTGGCGAAACAAATTCAAGCTGGTATTGTCATGGTTA ATAGCCCGTTCTCCGCGTTCCCAGGAACGCCGTTTGGCGGATATAAACAGTCCGGATTCGGACGTGAGCTTTGCATCGAA ACACTCGACTTATATACGGAAACGAAAAGCATCCTGTCTTATTATGGAAGCCGTCCGCTCAATCCTTTCGGCGTGTAA Protein sequence : MATVKEQKMEKLETKREMYHLIINGERVESASGETFTTYNPATGEPVAKVAKGTKEDAERAIQAARQAFDHGKWRHFPVN KRARILNKIASIMRSRFHELVELEILDTGKALSAAQGQVMQAIEDFEFYASAIISHRGTVNNMPGAFHNFTEKEPVGVCA QIIPWNYPLMMAAWKIAPAIAAGCSVVVKPASLTPLTCIVLAEICHEAGVPEGVVNVVTGSGSEVGNYLVEHPLVDKVAF TGSTPVGKNIMEKASKTLKRVTLELGGKSPNIIFEDADIDAAVNGSLFGIFYNTGQSCEARSRLYVHESIYDQFIEKFVE KTKKLKLGNPFEQDTHVGAIISREQLEVIDGYVKSAIEEGATIVTGGRKAKVEGFENGFWYEPTIITDVNHQMKVVKEEI FGPVVVVMKFNDENEVIKLANDSEYGLGSAIWTKDHARAIRVAKQIQAGIVMVNSPFSAFPGTPFGGYKQSGFGRELCIE TLDLYTETKSILSYYGSRPLNPFGV |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| VC0819 | NP_230467.2 | aldehyde dehydrogenase | Not tested | VPI-1 | Protein | 2e-76 | 42 |
| hpaE | AAO17179.1 | HpaE | Not tested | tcd island | Protein | 5e-82 | 42 |
| aldA | AAC12273.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 4e-79 | 41 |
| aldA | AAK20747.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 4e-79 | 41 |
| aldA | AAK20776.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 4e-79 | 41 |
| aldA-1 | YP_001216300.1 | aldehyde dehydrogenase | Not tested | VPI-1 | Protein | 1e-78 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| Geoth_1583 | YP_004587642.1 | betaine aldehyde dehydrogenase | VFG0082 | Protein | 8e-77 | 42 |
