Gene Information

Name : Geoth_1573 (Geoth_1573)
Accession : YP_004587632.1
Strain : Geobacillus thermoglucosidasius C56-YS93
Genome accession: NC_015660
Putative virulence/resistance : Virulence
Product : betaine aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.8
Position : 1502363 - 1503832 bp
Length : 1470 bp
Strand : +
Note : KEGG: gmc:GY4MC1_1481 aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase

DNA sequence : 
ATGAAAAAGTATCAGCTGTTTATTGATGGAAAATGGGTAGATTCTGTTTCAGGAAAAACGTTTACATCGATTAATCCAGC
AACGAAAGAAGTCAACGGAATCATCGCGGAAGGGGATGCGGCCGATATTGATTTAGCGGTAAAAGCGGCCCGCAAAGCAT
TTGAATCGGGGCCATGGGCTTCGATGTCTCCAAGTGAGCGTGGCCGATTATTGTATCGAGCTGCCCAAAAACTATGGGAG
AATGTTGATTATCTAGCAGAAGTTGAATCAAATGATAACGGGCTCACGATTAATGAAACAAAGCTGATCGCCATTCCAGC
TGCCATTGATGTACTTGAATTTTACGCGGGGATAGCAAACAAAATTCAAGGGGATACGCTTGCATCTCCAGCAAATCGTT
TTAATTATACGCTTCGTGAGCCAGTTGGTGTGGTCGGTGCCATTGTTCCGTGGAATTTTCCAATCATGCTGACAATGTGG
AAATTGGCGCCGGCACTGGCAGCGGGAAATACGATTGTGATCAAGCCGGCGGAACAAACACCAATCAGTGTGCTCGAATT
AGCAAGATTGTTGCAAGAAGCCGGTATTCCAGACGGGGTCATTAATGTGGTGAACGGTTACGGTCCTACAGCAGGGGCTG
CACTTGCTTCTCATCCAGATGTGGACAAAATAGCATTTACCGGTTCAACAGCAACAGGAAGGCTGATCATGCAGGCGGCA
AGTAAACATTTAAAGCCGATTTCCCTAGAATTAGGAGGGAAATCTCCGAATATTGTATTTGATGATGCTGATATGGATGC
GGCAATTAGCGGCTCATTATTTGGCATTTACTTTGCGCAAGGGCAAGTTTGCGCGGCAGGTTCAAGGCTGTTTGTTCAAG
AAACTATTTACGACCATTTCGTAGAGGAGTTTGCCCGCAAAGCGGAGTCCATTCGCGTTGGCCATCCGCTTGACCCGGCG
ACACAAATGGGCCCGCAAGTATCCGAAGAACAGTTAAATATCATTGATAGGTATGTTGAAATGGGCAAGCAAGAAGGGGC
CACGCTTGTAACAGGGGGAAAGCGAAAGGAAGAGTGCGGAAATGGGTTTTATTATACTCCGACCGTATTTGCAGATGTTG
ACAACAATATGACGATAGCAAAGGAAGAAATTTTTGGGCCTGTCGTATCCATTATTCGTTTTAAAGACGAAGAAGATGTA
TTAAAAAAGGCAAACGAAAGTATTTACGGATTAGCATCAGGTGTATGGACAACCAATTTGGCCCGCGCCCATCGAATGGC
ACGCGGATTGAAAGCGGGAACAGTGTATGTTAACACGTTCAGTATGTTAGACAGCGCTGCCCCGTTTGGCGGAATGAAAC
AAAGCGGATTTGGACGTGAGCTTGGTATAGAAGCAATGAACATGTATACACAAACGAAACATGTATGGGTGGATTTAAGT
CAAGAGAAATTCAATTGGTACGGCTTATAA

Protein sequence : 
MKKYQLFIDGKWVDSVSGKTFTSINPATKEVNGIIAEGDAADIDLAVKAARKAFESGPWASMSPSERGRLLYRAAQKLWE
NVDYLAEVESNDNGLTINETKLIAIPAAIDVLEFYAGIANKIQGDTLASPANRFNYTLREPVGVVGAIVPWNFPIMLTMW
KLAPALAAGNTIVIKPAEQTPISVLELARLLQEAGIPDGVINVVNGYGPTAGAALASHPDVDKIAFTGSTATGRLIMQAA
SKHLKPISLELGGKSPNIVFDDADMDAAISGSLFGIYFAQGQVCAAGSRLFVQETIYDHFVEEFARKAESIRVGHPLDPA
TQMGPQVSEEQLNIIDRYVEMGKQEGATLVTGGKRKEECGNGFYYTPTVFADVDNNMTIAKEEIFGPVVSIIRFKDEEDV
LKKANESIYGLASGVWTTNLARAHRMARGLKAGTVYVNTFSMLDSAAPFGGMKQSGFGRELGIEAMNMYTQTKHVWVDLS
QEKFNWYGL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 9e-90 46
hpaE AAO17179.1 HpaE Not tested tcd island Protein 1e-92 45
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-88 44
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 3e-92 44
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 3e-92 44
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 3e-92 44
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 8e-92 44
unnamed AAK01506.1 putative aldehyde dehydrogenase Not tested PAGI-1 Protein 9e-86 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Geoth_1573 YP_004587632.1 betaine aldehyde dehydrogenase VFG0082 Protein 6e-89 44