Gene Information

Name : Geoth_1557 (Geoth_1557)
Accession : YP_004587620.1
Strain : Geobacillus thermoglucosidasius C56-YS93
Genome accession: NC_015660
Putative virulence/resistance : Resistance
Product : methionine gamma-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.11
Position : 1485890 - 1487077 bp
Length : 1188 bp
Strand : +
Note : TIGRFAM: Methionine gamma-lyase; KEGG: gmc:GY4MC1_1463 methionine gamma-lyase; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme

DNA sequence : 
ATGAACAATACGAATAAACGAATGGAAACGATTGTTATTCATCATGGATATGATGTGGGATGGCATTTTGGCAGTTTGTC
CGTGCCGATTTTTCAAACATCGACATTTACGTTTGCCACGGCGGAACAAGGAGAAGCGCGGTTCGCAGGACGAGAAGACG
GATATATTTATTCGCGCCTGGCTAATCCGACAGTGCGGGTGCTGGAGGAAAAAATGGCGCGTTTGGAAGGAGGGGAAGCG
GCGCATGCGTTTAGTTCTGGGATGGCGGCCGTGTCCGCGGTATTGTTTGCGTTAACGAAAGCCAATGACCATATTATATG
TTCTCAGGGAGTATACGGCTGTACGTTTGGGCTGTTGCAATTGTTAAAAAAGAAATATCACGTTTCTCACGATTTTTGCG
CAATGGAAACGGAAGAGGAAATCCGCCGCCTTATCCGCCCGGAAACGGTTTGTATTTATGTGGAAACACCGATTAACCCA
ACGATGAAACTCATTGATTTGCAAATGGTCGTGAAAGTGGCAAAAGAGCATGGCATTACGGTTGTGGTGGACAATACGTT
TTGTTCGCCGTATTTGCAGCGGCCGCTTGAGCTTGGCTGTGATATCGTCGTGCATAGTGCGACGAAATATATCGGCGGCC
ATGGCGATGTCATTGCCGGCATCGCGGTTGGGAAAAAAGAATGGATGGAGGAAATCGCGAAAACAACGCAAAAAGATATC
GGCGGCGTCCTTTCTCCGTTTGCTGCTTGGCTGTTGTTGCGAGGATTAAAGACGCTTCCGGTGCGGATGGATCGGCATTG
CGATAATGCGGAGAAAATTGCCAAACGGTTAAAAGCCCATCCGCTCGTTGAACGCGTTAACTACCCTGCTGATTCAGACA
GCCGCGATTATCCGATTTACCGAAAACAAATGAAACGCGGCGGCGGCTTGATTTCGTTTGAAGTGAAAGGAACAAAACGA
GACGCCCAGCGTTTTCTTAATCACCTCCAGCTCATTCAAATCGCTGTCAGCCTTGGCGATACGGAAACATTAATTCAACA
TCCGGCAACGATGACCCATTCTGTTGTGCCGGAAGAAGCAAGAATAAAGATGGGGATCAGCGACCAATTGATCCGTTTAT
CCGTCGGTTTGGAGGCGTGGGAAGATATTTGGGATGATTTGGAGCAGGCGCTTGCTTCATTAAGATGA

Protein sequence : 
MNNTNKRMETIVIHHGYDVGWHFGSLSVPIFQTSTFTFATAEQGEARFAGREDGYIYSRLANPTVRVLEEKMARLEGGEA
AHAFSSGMAAVSAVLFALTKANDHIICSQGVYGCTFGLLQLLKKKYHVSHDFCAMETEEEIRRLIRPETVCIYVETPINP
TMKLIDLQMVVKVAKEHGITVVVDNTFCSPYLQRPLELGCDIVVHSATKYIGGHGDVIAGIAVGKKEWMEEIAKTTQKDI
GGVLSPFAAWLLLRGLKTLPVRMDRHCDNAEKIAKRLKAHPLVERVNYPADSDSRDYPIYRKQMKRGGGLISFEVKGTKR
DAQRFLNHLQLIQIAVSLGDTETLIQHPATMTHSVVPEEARIKMGISDQLIRLSVGLEAWEDIWDDLEQALASLR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-60 42
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-61 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Geoth_1557 YP_004587620.1 methionine gamma-lyase BAC0207 Protein 4e-88 49