Gene Information

Name : Geoth_1097 (Geoth_1097)
Accession : YP_004587175.1
Strain : Geobacillus thermoglucosidasius C56-YS93
Genome accession: NC_015660
Putative virulence/resistance : Resistance
Product : homocysteine desulfhydrase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.2
Position : 1077083 - 1078219 bp
Length : 1137 bp
Strand : +
Note : KEGG: gmc:GY4MC1_1027 Cys/Met metabolism pyridoxal-phosphate-dependent protein; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme

DNA sequence :
ATGAGACGAAAAACAAAACTGATTCATGGCGGCATCCCGGGCGATCCGCATACGGGAGCGGTTTCTGTTCCTATTTATCA
AGTCAGCACGTATAAACAAGAAGGAATCGGCGGCCATAAAGGCTTTGAATATTCGCGCACTGGCAACCCAACCCGCCACG
CATTGGAGCAACTGATTAAAGATCTGGAAGAAGGTTATGCCGGTTTTGCGTTTGGCTCCGGAATGGCGGCAATTACGGCG
GTCATGATGCTGTTTAACAGCGGCGACCACGTCATTTTAACGGACGACGTGTATGGCGGCACATACCGAGTCATGACGAA
AGTGTTAAACCGTTTGGGGCTTGAATCGACTTTTATTGATACAAGCGACCTTGCCAACATCGAAAAGCATATCCGGCCGA
ATACGAAGGCGCTCTACATTGAAACGCCAACCAACCCGCTTTTAAAAATTACTGACATTCAAGCTGCTTCCGCCATTGCC
AAAAACAATGGCCTGCTTACGATCGTGGACAACACGTTCAGCACCCCGTATTGGCAAACGCCGCTTGCTCTTGGCGCTGA
TATTGTTGTCCATAGTGCGACGAAATATTTAGGCGGCCATAGCGATGTTGTCGCTGGATTGGCGGTTGTCAATTCGGAAG
AGCTGGCAGAAAAACTGCATTTTGTGCAAAACTCTACCGGAGGAATTCTCGGCCCGCAAGATTCATGGCTTTTAATCCGA
GGCATCAAGACGCTTGGCGTGCGCATGGAGGAGCATGAAGAAAACACGAGAAACATCGTGGAATTTTTAGTGAACCATCC
GGCGGTCCAAAAAGTGTATTATCCGGGATTGGAAACACATCCAAACCATGAGATTGCCAAAAAACAAATGCGCGGATTTG
GCGGCATGGTCTCTTTTGATGTCGGAAGCGCGGAAAAGGCTGAGCAAGTGTTAAACCGCGTCCGTTATTTTACGCTCGCG
GAAAGCTTGGGAGCAGTCGAAAGCTTAATTTCGCTGCCAGCGAAAATGACGCATGCGTCCATTCCGAAAGAGCGCCGCGA
ACAATTGGGCATTACCGATGGACTGATCCGCATTTCTGTTGGATTGGAAGATGCCGAAGATTTAATCGAAGATTTAGCCC
AAGCATTGCATGGTTAA

Protein sequence :
MRRKTKLIHGGIPGDPHTGAVSVPIYQVSTYKQEGIGGHKGFEYSRTGNPTRHALEQLIKDLEEGYAGFAFGSGMAAITA
VMMLFNSGDHVILTDDVYGGTYRVMTKVLNRLGLESTFIDTSDLANIEKHIRPNTKALYIETPTNPLLKITDIQAASAIA
KNNGLLTIVDNTFSTPYWQTPLALGADIVVHSATKYLGGHSDVVAGLAVVNSEELAEKLHFVQNSTGGILGPQDSWLLIR
GIKTLGVRMEEHEENTRNIVEFLVNHPAVQKVYYPGLETHPNHEIAKKQMRGFGGMVSFDVGSAEKAEQVLNRVRYFTLA
ESLGAVESLISLPAKMTHASIPKERREQLGITDGLIRISVGLEDAEDLIEDLAQALHG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-112 60
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 9e-114 60
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-80 47

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Geoth_1097 YP_004587175.1 homocysteine desulfhydrase BAC0207 Protein 3e-69 42