Gene Information

Name : Halxa_0428 (Halxa_0428)
Accession : YP_004585835.1
Strain :
Genome accession: NC_015658
Putative virulence/resistance : Resistance
Product : heavy metal translocating P-type ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : 3.6.3.3
Position : 144780 - 147149 bp
Length : 2370 bp
Strand : +
Note : TIGRFAM: ATPase, P-type, heavy metal translocating; ATPase, P-type, heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating; ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; KEGG: hma:pNG6135 cation-transporting ATPase; PFAM: ATPase, P-type, ATPase-associated reg

DNA sequence : 
ATGACAGACGGAACCGCAGCGCGGCAGACGAGTGGGGGTGGGCAGCAGACGTTGACCGCCCGGCTCGCGGTCCCCGAGAT
GGACTGTCCCTCCTGCGCGGGGAAGGTGGACAAGAGCCTGCAACGCGTCGAGGGCGTTGTCGACGCCGATCTCAATCCGA
CGACCGGGACGGCAACCGTCACGTACGATCCCGAGCAAACTGCCGAGAGCGATGTAGTGGCAGCGATCGAAGGAGCGGGA
TACGAGGTGACTGGCGGAACCGGCGGTGACGCCGACACCGAGACCGGCCAGTCGTCCGACGGCGTCGACGTCGCACCGCC
TACGGAAGTCTGGACGACTCCGCGAGCGAAGAAGACGTGGCTCGGCGCGGCGTTCGTCGTCTTCGGGCTACTCTTCGAGT
TCGTCCTCGAGGCGCAGAACGTCGCCGTCGCGAGCGTCCTCGGGACGCCGCTTTCGATCGCCGATGTCCTGTTTCTCGGA
GCCGTCGCAGCCAGCGGCGTGCCGGTCGTCCGGAGCGGCTACTACTCGGCGCGCAACCGCAGCCTCGACATCGACCTCCT
GATGGGGACGGCGATCGTCGCCGCCACCGGGATCGGCTACTTCGTCGAGGCGGCGACGCTGGCCGTCCTGTTCAGCATCG
CCGAACTGCTCGAGGACTACGCGATGGACAGGGCCCGCGACTCCCTGCGCGAGCTGATGGAGCTCTCGCCCGACGAGGCG
ACGGTCTACCGCGACGGCGAGGAAGTGACCGTCCCCGCGGAGGACGTCAGCGTCGGCGAAACCGTCATCGTCCGCCCGGG
TGAGAAGATACCGCTCGACGGGACCGTCCAGGACGGCGAGAGCGCGGTCGACGAGTCGCCGATCACCGGCGAGAGCGTCC
CCGTCGACAAGACGCCCGGCGACGAAGTGTACGCCGGCGCGATCAACGAGGAGGGGTACCTCGAGGTCGAGGTGACCTCG
ACGGCGGGCGACTCGACGCTCTCGCGGATCATCGAGTTGGTGCAGGGCGCACAGGCCAAGCAGACGGACACCGAGCAGTT
CGTCGACCGGTTCGCGGGCTACTACACGCCGCTGGTAGTGGCGCTGGCGATCCTGACCGCGGCCGTCCCGCCGCTTCTCA
TCGGTGATTCCGTCGCGACGAGCGTCCTCGGCTACGAGTTCGTCTTCGCCGCCGACTGGGGAACGTGGTTCGTGCGCGGG
CTCACGCTGCTGGTGATCGCCTGTCCTTGCGCGTTCGTCATCTCGACGCCGGTCTCGGTGGTCTCGGGGATTACGAGCGC
CGCGAAGAACGGCGTCCTTATCAAGGGCGGCAACTACCTCGAGGCGATGGGCGAGGTCGACGCCGTGGCCCTCGACAAGA
CGGGCACGCTCACGAAGGGCGAGCTCGCGGTTACCGACGTCGTCCCGCTCGACGAAACGAGCGAGACCGATCTCCTCCGG
TACGGTGCCGGCTTGGAGCGACGCAGCGAACACCCGATCGCCGACGCAGTGCTGACCCGCGCCGACGAGGCGGGGCTGGA
CGACTTGCCCGAGCCGTCGTCGTTCGAGAGCCTCACCGGCAAGGGAATTCGCGGCGAGATCGACGGCGAAACCTACTACG
CCGGCAAGCCGGCACTCTTCGAAGACCTCGGCTTCGATCTCTCTCGAGCGCGTCGTCCGACAGAGACCGACGGCGGCGTC
GCTGCGGGCTCGACTACGGTGGCGGATGACTCCGCCTTCAGCGAAGAGACGCTCGCCGAACTCGAGCGGGAGGGAAAGAC
GGTCGTCCTCGTCGGCACGGCGTCGAGGCTGCTCGGTGCGATTGCGATCGCCGACGAGGTTCGGCCCGCTTCGAAGCGAG
CCGTCGAACGCCTCCACGAGTTGGGCGTCGACCGCGTCGTGATGCTCACCGGCGACAACGAGGGGACCGCCCGCGCGATC
GCCGACGAGGTCGGCGTCGACGAGTACCGCGCCGAACTCCTGCCCGACGAGAAAGTCGACGCGATCGAGGCCTTGCAGCG
CGAGTATGGAACCGTGGCGATGGTCGGCGACGGCATCAACGACGCGCCGGCGCTTGCGACCGCTGAGGTCGGGATCGCGA
TGGGCGCTGCAGGGACGGACGCAGCTCTCGAGACAGCCGACATCGCGCTGATGGGCGACGATATCGGCAAGCTTCCGTAC
CTGTACGCGCTCTCGAACACGGCAAACGGCGTCATCCGCCAGAACATCTGGGCGAGTCTCGGCGTGAAACTCCTGCTCGC
GATCGGCGTGCCGTTGGGACTCGTCAGCGTCGCGATGGCCGTCGTCGTCGGCGACATGGGGATGAGCCTCGGCGTGACCG
GGAACGCGATGCGACTCTCCCGGCTACAGCCCGACCGGTTCTTCGACTGA

Protein sequence : 
MTDGTAARQTSGGGQQTLTARLAVPEMDCPSCAGKVDKSLQRVEGVVDADLNPTTGTATVTYDPEQTAESDVVAAIEGAG
YEVTGGTGGDADTETGQSSDGVDVAPPTEVWTTPRAKKTWLGAAFVVFGLLFEFVLEAQNVAVASVLGTPLSIADVLFLG
AVAASGVPVVRSGYYSARNRSLDIDLLMGTAIVAATGIGYFVEAATLAVLFSIAELLEDYAMDRARDSLRELMELSPDEA
TVYRDGEEVTVPAEDVSVGETVIVRPGEKIPLDGTVQDGESAVDESPITGESVPVDKTPGDEVYAGAINEEGYLEVEVTS
TAGDSTLSRIIELVQGAQAKQTDTEQFVDRFAGYYTPLVVALAILTAAVPPLLIGDSVATSVLGYEFVFAADWGTWFVRG
LTLLVIACPCAFVISTPVSVVSGITSAAKNGVLIKGGNYLEAMGEVDAVALDKTGTLTKGELAVTDVVPLDETSETDLLR
YGAGLERRSEHPIADAVLTRADEAGLDDLPEPSSFESLTGKGIRGEIDGETYYAGKPALFEDLGFDLSRARRPTETDGGV
AAGSTTVADDSAFSEETLAELEREGKTVVLVGTASRLLGAIAIADEVRPASKRAVERLHELGVDRVVMLTGDNEGTARAI
ADEVGVDEYRAELLPDEKVDAIEALQREYGTVAMVGDGINDAPALATAEVGIAMGAAGTDAALETADIALMGDDIGKLPY
LYALSNTANGVIRQNIWASLGVKLLLAIGVPLGLVSVAMAVVVGDMGMSLGVTGNAMRLSRLQPDRFFD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 9e-122 46
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 2e-121 45
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 2e-121 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Halxa_0428 YP_004585835.1 heavy metal translocating P-type ATPase BAC0298 Protein 1e-98 44
Halxa_0428 YP_004585835.1 heavy metal translocating P-type ATPase BAC0092 Protein 2e-87 41
Halxa_0428 YP_004585835.1 heavy metal translocating P-type ATPase BAC0100 Protein 3e-65 41