Gene Information

Name : FsymDg_0713 (FsymDg_0713)
Accession : YP_004582156.1
Strain : Frankia sp. 4085684
Genome accession: NC_015656
Putative virulence/resistance : Resistance
Product : cystathionine gamma-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.1
Position : 830748 - 832061 bp
Length : 1314 bp
Strand : -
Note : KEGG: fri:FraEuI1c_6724 Cys/Met metabolism pyridoxal-phosphate-dependent protein; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme

DNA sequence : 
ATGACCAGCGCCGACGATCCTGTGACCAGCGATCCTGTGGCCAACGATCCTGTGGCCGACAACGCGGTAACCGGTGTGGA
CGGCTCCGCGGCCCGTGCCGACGGCCCGCGCCGCCCGGCGCCCGTCGGCGCATGGCCGGCCGGCGCCGAGGCCTGGGCCG
GTACCGGCTTCGAGACGGTGGCGATCCACGCGGGACAGGACCCCGACCCCGTCACCGGCGCGGTGGTCGTCCCCATCCAC
CCGTCGTCGACGTTCGCGCAGGACGCTGTCGGGGTCCCGCGCGGGGCGTACGAGTACGCCCGCTCGTCCAACCCGACCCG
CACCGCGCTGGAGACCTCCCTGGCCGCGCTGGAGGCGGGTGCGGTGGGGCTCGCCTTCGCCTCCGGTATGGCCGCCGTGG
ACGCGGTGCTGCGCACGGTGTGCCGACCCGGCGACCACGCGGTGATCCCGTTGGACGCCTACGGTGGCACCTACCGACTG
TTCTCGCGGGTGCTCGCCGAGTGGGGCGTGGAGTACACCCCGGCGCCGCTGAACGATCTCGACGCGGTGCGGGCGGCGAT
CCGCCCGGGCCGTACCCGGCTACTGTGGTCCGAGACGCCGACGAATCCGACGCTGGGTGTCTCCGACATCGCCGCGCTGG
CCGATATCGCGCACTCCGCCGACGCGCTGCTCGTCGTCGACAACACCTTCGCCACCCCGTACCTGCAGCAGCCCCTGGCC
CTCGGTGCCGACGTGACGGTCCACTCGACCACGAAGTACCTCGGCGGACACAGTGACGTCGTCGGTGGCGCCGCGGTGGT
GGCCGACCCGGGGCTGGGGGAACGGCTGCGGTTCATCCAGAACGCCACCGGGGCGGTTCCCAGCCCGTTCGATGCCTGGC
TGGTGCTGCGGGGGGCGAAGACCCTGGCGGTCCGGATGGACCGGCACTGCACGAACGCCCGCCGCGTCGCGGAGCTGCTG
GCGGGGCATCCCGCGGTGGCGGCCGTGCACTACCCGGGCCTGCCGGACGACCCGGGCCACCAGGTGGCGGCGAAGCAGAT
GCGTGACTTCGGCGGGATGGTGTCGTTCGCCCTGCGCGGGGGCGAGGAGGCTGCGGTCGAGGTGTGCCGGCGGACCAGGG
TGTTCACCCTCGCCGAGTCCCTGGGCGGCGTCGAGTCGCTCATCGAGCATCCCGGGCGGATGACGCACGTCTCGGTGGCC
GGTTCTCCGCTGGAGGTGCCCGCGAACCTCATCCGGCTGTCGGTCGGCATCGAGTCGATCGACGACCTGCTCGAGGACCT
CACCGAAGCCCTCCCCGACCGCCGGGATCCGTAG

Protein sequence : 
MTSADDPVTSDPVANDPVADNAVTGVDGSAARADGPRRPAPVGAWPAGAEAWAGTGFETVAIHAGQDPDPVTGAVVVPIH
PSSTFAQDAVGVPRGAYEYARSSNPTRTALETSLAALEAGAVGLAFASGMAAVDAVLRTVCRPGDHAVIPLDAYGGTYRL
FSRVLAEWGVEYTPAPLNDLDAVRAAIRPGRTRLLWSETPTNPTLGVSDIAALADIAHSADALLVVDNTFATPYLQQPLA
LGADVTVHSTTKYLGGHSDVVGGAAVVADPGLGERLRFIQNATGAVPSPFDAWLVLRGAKTLAVRMDRHCTNARRVAELL
AGHPAVAAVHYPGLPDDPGHQVAAKQMRDFGGMVSFALRGGEEAAVEVCRRTRVFTLAESLGGVESLIEHPGRMTHVSVA
GSPLEVPANLIRLSVGIESIDDLLEDLTEALPDRRDP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-57 44
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-58 44
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 7e-52 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
FsymDg_0713 YP_004582156.1 cystathionine gamma-lyase BAC0207 Protein 9e-55 45