Gene Information

Name : FsymDg_1191 (FsymDg_1191)
Accession : YP_004582606.1
Strain : Frankia sp. 4085684
Genome accession: NC_015656
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : 3.5.1.5
Position : 1405040 - 1406770 bp
Length : 1731 bp
Strand : -
Note : PFAM: Amidohydrolase 1; Urease alpha-subunit, N-terminal; TIGRFAM: Urease, alpha subunit; HAMAP: Urease subunit alpha; KEGG: fal:FRAAL1447 urease subunit alpha

DNA sequence :
GTGAGCCGCCACCTCGACCGGGCCCGCTACGCCGACCTGTACGGGCCGACCGTCGGCGACCGCGTCCGCCTCGCCGACAC
CGACCTGTTCATCGAGGTCACCGAGGACCGCAGCCGCGGGCCCGCCGGTGCCGGCACCGGCGACGAGGCGGTGTTCGGCG
GCGGCAAGGTGATCCGGGAGTCCATGGGGCAGGCCCGGGCGTCGCGCGCCGAAGGCGCCCCGGACCTGGTCATCACCGGC
GCGGTCGTCCTCGACCACTGGGGGGTCGTCAAGGCCGACGTCGGCATCCGCGACGGGCGGATCGTCGCGCTCGGCAAGGC
CGGCAACCCCGACATCATGGACGGCGTCCATCCCGACCTGGTCATCGGACCGGGCACGGAGATCCTCGCCGGCAACGGGA
AGATCCTCACCGCGGGGGCGGTGGACTGCCACGTCCACCTGATCTGCCCGCAGCAGGTCCCCGAAGCCCTCGGCGCCGGC
ATCACCACCCTGATCGGCGGCGGGACCGGGCCCGCCGAGGGCACCAAGGCCACGACCGTCACCCCCGGCCCGTGGAACCT
CGCCCGGATGCTGTCGGCGATGGACGCGCTGCCGGTCAACGTCGTCCTGCTCGGCAAGGGCAACACCGTGGGTGAGGGCG
CCCTGTGGGAGCAGCTGCGCGGCGGTGCCGCCGGCTTCAAACTGCACGAGGACTGGGGCTCCACACCGGCGGCGATCGAC
GCCTGCCTGCGGGTCGCGGACGCCTCCGGGGTGCAGGTCGCGCTGCACTCCGACACCCTCAACGAGGCCGGTTTCGTCGA
GGACACCCTGGCCGCGATCGCCGGCCGGGCCATCCACGCCTACCACACCGAGGGTGCCGGCGGTGGGCACGCCCCGGACA
TCATCACCGTGGCCGCGGCAGCGAACGTCCTGCCGAGCTCGACGAACCCGACCCGCCCGCACACCGTCAACACCCTCGAC
GAGCACCTCGACATGCTCATGGTCTGCCACCATCTGAATCCGACCGTGCCCGAGGACCTGGCCTTCGCCGAGAGCCGCAT
CCGGCCGTCCACGATCGCCGCCGAGGACGTCCTGCACGACCTCGGCGCCATCTCGATGATCGGTTCGGACTCGCAGGCCA
TGGGACGCATCGGCGAGGTCGTGCTGCGCACCTGGCAGACCGCGCACGTGATGAAGGCCAGGCGCGGCCCACTGCCCGGG
GACGGGCGCGCCGACAACGCCCGCGCCCGCCGGTACGTCGCCAAGTACACGATCTGCCCGGCCGTCGCGCATGGCCTGGA
CGCCGAGATCGGCTCGGTGGAGCCGGGCAAGCTCGCCGACCTGGTGCTCTACGATCCGGCGTTCTTCGGCGTCCGGCCGG
CCGTCGTCATCAAGGGCGGGTTCGTGGCCTGGGCGGCGATGGGCGACGCGAACGCCTCCATCCCCACCCCGCAGCCGGTG
CTGCCGCGCCCGATGTGGGGGGCGGCGGCGGGCCCGGCCGCGGCGTCGTCACTGTCGTTCGTCGCCCCCGCGGCCCTCGA
CGCCGGCCTGCCGGCGCGCCTCGGCCTGGCCAAACCGATGGCCGCGGTCGCCGACGTCCGCCGCCGCGGCAAGGCGGACC
TGCCCGAGAACACCGCCACCCCCGACATCCACGTCGACCCGGAAACATTCACCGTCACCGTCGACGGCGACACGATAGAA
CCCGCCCCGGTAGCCGAACTCCCCATGGCCCAGCGCTATTTCCTCTTCTGA

Protein sequence :
MSRHLDRARYADLYGPTVGDRVRLADTDLFIEVTEDRSRGPAGAGTGDEAVFGGGKVIRESMGQARASRAEGAPDLVITG
AVVLDHWGVVKADVGIRDGRIVALGKAGNPDIMDGVHPDLVIGPGTEILAGNGKILTAGAVDCHVHLICPQQVPEALGAG
ITTLIGGGTGPAEGTKATTVTPGPWNLARMLSAMDALPVNVVLLGKGNTVGEGALWEQLRGGAAGFKLHEDWGSTPAAID
ACLRVADASGVQVALHSDTLNEAGFVEDTLAAIAGRAIHAYHTEGAGGGHAPDIITVAAAANVLPSSTNPTRPHTVNTLD
EHLDMLMVCHHLNPTVPEDLAFAESRIRPSTIAAEDVLHDLGAISMIGSDSQAMGRIGEVVLRTWQTAHVMKARRGPLPG
DGRADNARARRYVAKYTICPAVAHGLDAEIGSVEPGKLADLVLYDPAFFGVRPAVVIKGGFVAWAAMGDANASIPTPQPV
LPRPMWGAAAGPAAASSLSFVAPAALDAGLPARLGLAKPMAAVADVRRRGKADLPENTATPDIHVDPETFTVTVDGDTIE
PAPVAELPMAQRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 8e-151 60
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 8e-151 60
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-148 57
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 5e-149 57
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 5e-149 57
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 5e-149 57

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
FsymDg_1191 YP_004582606.1 urease subunit alpha VFG0270 Protein 4e-132 54