Gene Information

Name : Metok_1382 (Metok_1382)
Accession : YP_004577125.1
Strain : Methanothermococcus okinawensis IH1
Genome accession: NC_015636
Putative virulence/resistance : Unknown
Product : adenine-specific DNA methyltransferase
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0286
EC number : 2.1.1.72
Position : 1426762 - 1428381 bp
Length : 1620 bp
Strand : -
Note : KEGG: mhu:Mhun_2789 N-6 DNA methylase; PFAM: DNA methylase, adenine-specific

DNA sequence :
ATGAAGTTAAAGAAGAAACAGGAAATGTTAAAAAAACTTGAAAAAACATTATGGGGTAGTGCTGAAAAACTAAGGGGTAG
TGTTGACCCTTCAAGATATAAAGATATAGTATTGGGCATTATATTCTTAAAATATGCTTCTGATATGTTTGAAGAAAGAA
GAAGAGAATTAATTGATTTATCTAAAAATCCCAAAAGTGATTATTATTGTGAAACAGAAGATGAGCTCATAGGACTTTTA
GAAGATAATGAGGAATATATTTCTGAAAATGTTTTTTATGTTCCTGAACAATCAAGGTGGGATTATTTAATAAAAAATGC
GAAAAATCCAAATATTGCCAAGTTATTGGATGATGCAATGATTTTGCTTGAAAAACATAACAGTAAATTAAAGGGAGTAT
TACCTAAGGAATATGTAAGGGCAGAAATTCCACATGAGAAATTAGGGGCATTACTTGATTTATTTAATAATATTAATTAT
AAGGAATTTATAGAAAACAAGGATGAAAGTATAGGGGATGTATTCGGAACAATTTATGGGTATTTTATGAGGAACTTTTC
CCAGAAATTGGGGCAGAAAGGGGGTGAGTTCTTTACTCCTGAATGTATTGTAAAACTGCTTGTTGAGTTGGTGGAGCCGT
TAAGAGGTAGAATATACGACCCTGCATGTGGTAGTGGTGGAATGTTTGTTCAGAGCTCTAAGTTTGTAAAGGAGTATTTA
AAAAATGGAAATGGTATAGATTTAGCAATATATGGTCAGGAGTTGAATTCCTCAAATGTTAGAATATGTAAAATGAACCT
TGCGATACATAGATTATCCCATGACCAGATAAAACAGGGAGACACGCTATCAAATGATAAACATAGGGATTTAAAAGCAG
ATTATATTATTACAAATCCGCCGTTTAACTACAAGGATTATGACCAAAAGGTTTTGGAAGGAGATGTAAGGTTTCCCTAT
GGAATTGTTCCAAAAAAGGCAGAAAATGCAAAAAGTGGGAATGCAAACTTTTTATGGATACAGCATTTTATTTATCATTT
ATCGGATAATGGCATAGCTGCTTTTATTATGGCTAATGGTTCCCTATCTGCTGGTGGTAAAGAAGGGGAGATAAGAAAAA
AGATAATAGAAGAAGGTATTGTAGATTGTATAATATCACTACCTAATAAGATGTTTTATACTACGCAAATTCCCGCTTGT
ATATGGGTAATAGACAAAAACAAAGAGAATGGAAGGTTTAGAAGTAGGAAATGGGAAACTCTATTTATAGATGCAAGGGA
AATTTACACCCCCGTAGCAAGAAATCAGAACGAATTTTCAGATGAACAGATTAAAAAAATAGCTGATGTTTATAGATGTT
ATAGGGGAGAGGATGGCTATCCAGATTATAAGGATGAAAAGGGATTCTGTAAAGTTGCTACGATAGATGAAATAAGAGAA
CAAGATTATATTTTAACTCCTGGGCGTTATGTTGGAATTGCAGATGTTGAAGAAGACTCAGAACCTTTTGAAGATAAAAT
GGAAAGATTGACTAAGGAATTATCAGAACACTTTAAAAAATCGAGAGAATTAGAAGAAAGAATAAAGAATAATTTAAGTG
AATTGGGATTTAAGGCATAA

Protein sequence :
MKLKKKQEMLKKLEKTLWGSAEKLRGSVDPSRYKDIVLGIIFLKYASDMFEERRRELIDLSKNPKSDYYCETEDELIGLL
EDNEEYISENVFYVPEQSRWDYLIKNAKNPNIAKLLDDAMILLEKHNSKLKGVLPKEYVRAEIPHEKLGALLDLFNNINY
KEFIENKDESIGDVFGTIYGYFMRNFSQKLGQKGGEFFTPECIVKLLVELVEPLRGRIYDPACGSGGMFVQSSKFVKEYL
KNGNGIDLAIYGQELNSSNVRICKMNLAIHRLSHDQIKQGDTLSNDKHRDLKADYIITNPPFNYKDYDQKVLEGDVRFPY
GIVPKKAENAKSGNANFLWIQHFIYHLSDNGIAAFIMANGSLSAGGKEGEIRKKIIEEGIVDCIISLPNKMFYTTQIPAC
IWVIDKNKENGRFRSRKWETLFIDAREIYTPVARNQNEFSDEQIKKIADVYRCYRGEDGYPDYKDEKGFCKVATIDEIRE
QDYILTPGRYVGIADVEEDSEPFEDKMERLTKELSEHFKKSRELEERIKNNLSELGFKA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hsdM YP_251979.1 type I restriction-modification system DNA methylase Not tested SCCmec Protein 2e-117 50
hsdM BAH57701.1 type I restriction-modification system DNA methylase Not tested Type-VII SCCmec Protein 2e-117 50
hsdM BAD24842.1 HsdM protein Not tested Type-V SCCmec Protein 5e-115 48