Gene Information

Name : clpB (MLP_06170)
Accession : YP_004571034.1
Strain : Microlunatus phosphovorus NM-1
Genome accession: NC_015635
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease ATP-binding subunit ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 678551 - 681145 bp
Length : 2595 bp
Strand : +
Note : -

DNA sequence :
ATGGACACCAACAAGCTCACTACCAAGAGTCGCGATGCGGTCTCGGCCGCGTTGCGCAACGCATTGACCGCCGGCAACCC
GACTGCTGAGCCGGTCCATCTTCTGCACGCCCTGCTGATGGTGCCGGGCAACACCGTCGCACCGCTGCTTGCTGCGGTCG
GCGCCGACCCGGCTGTGGTCGATGCCGCCGCCCAGGGCGCGATCACCAAGCTTCCGACGACCAGCGGCTCCTCGGTCAGC
CAACCGAACGTGTCCGGCTCGTTCGCCCGGGTGCTCGCCGACGCGGAGACTCGCGCCGAGCAGCTCGGCGACGCGTACGT
CGCCACCGAGCATCTGCTGATCGCGCTGTCCGCGGTCCAGTCCGATGCCAAGAAGATCCTCAGCGACCTGCGCGTGACCG
CCGACGGTCTGACCGCGGCGTTCAGCGCATCCCGGGGTAGCAAGCGGGTCACGTCGCAGGAGGCGGAGGGCACCTCCTCG
GCGCTCGACCAGTACGGTGTCGACCTCACCGAGCAGGCCCGCGAGGGCAAGCTCGACCCGGTGATCGGCCGCGACACCGA
GATCCGGCGTGTGGTGCAGGTGCTGGCCCGGCGGACGAAGAACAACCCGGTGCTGATCGGTGAGCCTGGCGTCGGCAAGA
CCGCCGTCGTGGAGGGACTTGCCCAGCGGCTGGTGGCTGGTGACGTGCCCGACTCCTTGAAGGGACGTCGGCTCGTCTCG
CTGGACCTGTCGGCGATGGTCGCCGGCGCGAAATACCGGGGCGAGTTCGAAGAGCGGCTCAAGGCGGTGCTGACCGAGAT
CCGCGACGCCGAGGGCCAGATCATCACGTTCATCGACGAACTGCACACCGTGGTCGGCGCCGGTGCTTCCGGCGACTCCT
CGATGGATGCCGGCAACATGCTGAAGCCGATGCTGGCTCGTGGCGAGCTGCGGATGATCGGTGCCACGACCCTGGACGAG
TATCGGGAGCGGATCGAGAAGGACCCCGCCCTCGAGCGCCGCTTCCAGCAGGTCTACGTCGGTGAGCCGAGCGTGGAGGA
CACGATCGCCATCCTGCGCGGGCTGCGGGAGCGGTACGAGGCGCACCACAAGGTGGTGATCACCGACGCCGCTCTGGTGG
CGGCGGCGAGCCTGTCCAACCGCTACATCACCTCCCGGCAACTGCCGGACAAGGCGATCGATCTGATCGACGAGTCCGCC
TCGCGGCTGCGGATGGAGATCGACTCATCCCCGGAGGAGATCGATCAGCTGCGCCGCACGGTGGACCGGATGAAGATGCA
GCAGTTCGCGCTGGAGAAGGAATCCGACACCGGCTCGGTCGAGCGGCTGCGCCGGCTGGAGAGCGAGCTGGCCGACGCCC
AGGAGGAGTTGCGCGGGCTCGAGGCGCGCTGGGACGCCGAGAAGCAGGGTCTCAACCAGGTCGGTGATCTGAAGGCTCGG
ATCGACGAGCTGCGGATCGAGGCCGACCGGGCATTGCGGGAGGGCAACCTCGTACGCGCCAGCGAGATCAACTATGGCGA
GATCCCGGAGTTGCAGCACCAGCTCGCACGTGCGGACCAAGCCGAGAGCCAGACGACCTCGATGGTCTCGGAGGAAGTCG
GCCCGGGCGACATCGCCGAGGTCGTCTCCAACTGGACCGGCATCCCGGTGGGTCGGCTGCTGCAGGGCGAGAGCGAGAAG
CTGCTGCACATGGAGGACCGGCTGGGCGAACGGCTGATCGGCCAGAAGAAGGCGGTCAAGGCCGTCTCCGATGCGGTACG
GCGGTCTCGCGCCGGGATCTCCGATCCAAACCGGCCGACCGGATCGTTCCTGTTCCTCGGCCCGACCGGCGTCGGCAAGA
CCGAACTGGCCAAGTCGCTGGCGGAGTTCTTGTTCGACGACGAGCACGCCATGATCCGGATCGACATGAGCGAATACTCC
GAGAAGCACTCGGTGGCGCGATTGGTCGGTGCGCCCCCTGGCTATGTCGGCTATGAGGAGGGTGGGCAGCTCACCGAGGC
GGTGCGGCGCCGTCCGTACGCGGTCGTGTTGCTGGACGAGGTCGAGAAGGCCCACAGCGAGGTCTTCGACATCTTGCTGC
AGGTGCTCGACGACGGTCGGCTGACCGACGGTCAGGGGCGGACGGTCGACTTCCGCAACGTGCTGCTGATCCTCACCTCC
AACCTGGGATCGCAGTTCCTCGCGGACCAGACCCTGAACCCGGAGACCAAGCGGGACGCGGTGATGGGCGTGGTCCGTGG
TGCCTTCAAGCCGGAGTTCCTCAACCGGCTCGACGAGATCGTGCTGTTCGACGCGCTCAACACCGAGGATCTGGCCAAGA
TCGTCGAGATCAGCCTGCGCCGGCTGAACGCCCGACTGGCCGATCGTCGGATCACCGTCGAGGTCACGTCGGCCGCGAAG
GACTGGCTGGCTCTGACCGGCTTCGACCCGGTCTACGGTGCTCGTCCGCTGCGTCGGCTGATCCAGACCACGATCGAGGA
CCAACTGGCTCAACTCGTGCTGAGCGGGGTAGTCACCGACGGCGACACGATCACCTTCGATGTCGACGAAACCTCCGACG
GTTTGGTCGTCCAGTCGGCAGGCGTGACGGTCTGA

Protein sequence :
MDTNKLTTKSRDAVSAALRNALTAGNPTAEPVHLLHALLMVPGNTVAPLLAAVGADPAVVDAAAQGAITKLPTTSGSSVS
QPNVSGSFARVLADAETRAEQLGDAYVATEHLLIALSAVQSDAKKILSDLRVTADGLTAAFSASRGSKRVTSQEAEGTSS
ALDQYGVDLTEQAREGKLDPVIGRDTEIRRVVQVLARRTKNNPVLIGEPGVGKTAVVEGLAQRLVAGDVPDSLKGRRLVS
LDLSAMVAGAKYRGEFEERLKAVLTEIRDAEGQIITFIDELHTVVGAGASGDSSMDAGNMLKPMLARGELRMIGATTLDE
YRERIEKDPALERRFQQVYVGEPSVEDTIAILRGLRERYEAHHKVVITDAALVAAASLSNRYITSRQLPDKAIDLIDESA
SRLRMEIDSSPEEIDQLRRTVDRMKMQQFALEKESDTGSVERLRRLESELADAQEELRGLEARWDAEKQGLNQVGDLKAR
IDELRIEADRALREGNLVRASEINYGEIPELQHQLARADQAESQTTSMVSEEVGPGDIAEVVSNWTGIPVGRLLQGESEK
LLHMEDRLGERLIGQKKAVKAVSDAVRRSRAGISDPNRPTGSFLFLGPTGVGKTELAKSLAEFLFDDEHAMIRIDMSEYS
EKHSVARLVGAPPGYVGYEEGGQLTEAVRRRPYAVVLLDEVEKAHSEVFDILLQVLDDGRLTDGQGRTVDFRNVLLILTS
NLGSQFLADQTLNPETKRDAVMGVVRGAFKPEFLNRLDEIVLFDALNTEDLAKIVEISLRRLNARLADRRITVEVTSAAK
DWLALTGFDPVYGARPLRRLIQTTIEDQLAQLVLSGVVTDGDTITFDVDETSDGLVVQSAGVTV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 3e-162 52
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 5e-111 42
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 2e-110 41
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 2e-110 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB YP_004571034.1 ATP-dependent Clp protease ATP-binding subunit ClpB VFG2076 Protein 4e-122 45
clpB YP_004571034.1 ATP-dependent Clp protease ATP-binding subunit ClpB VFG2084 Protein 2e-114 43