Gene Information

Name : folA (MLP_38770)
Accession : YP_004574294.1
Strain : Microlunatus phosphovorus NM-1
Genome accession: NC_015635
Putative virulence/resistance : Resistance
Product : dihydrofolate reductase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0262
EC number : 1.5.1.3
Position : 4178097 - 4178576 bp
Length : 480 bp
Strand : -
Note : -

DNA sequence :
GTGATCGGTATCGCCGCCGTCGCCCGCAACGGCGTGATCGGCGCAGGCAATGACATCCCATGGCGGATCAAGGAGGACTG
GGCCCGGTTCAAGGCGATCACCATGGGCCACGTCTTGATCATGGGTCGCAAGACGTATGACTCGATCGGCCGTCCGCTGC
CCGGCCGGACGACCATCGTGGTGACTCGTGATCCCGACTGGACCGCCGACGGCATCCGGACCGCCCACAACCTGGATGAC
GCGTTCGAGGTGGCGTACGCGTTGGCGCCGGAGAAGGTGTTCGTGGCAGGCGGCGGGCAGATCTATGCCGCGGCCTGGGA
CCGGCTGGACGTCTTGGAGATCACCGAGGTCGACATTGAACCGGCCGGCGAGGTGCGTTTCCCGCTGATCGGGCCCGAGT
GGGTGGTGGTCAGCCGCGAGCAGGCGGACGGCTATGCCTTCGTCACCCTCGAGAAGGATACTGAATCGATACTGAATTAG

Protein sequence :
MIGIAAVARNGVIGAGNDIPWRIKEDWARFKAITMGHVLIMGRKTYDSIGRPLPGRTTIVVTRDPDWTADGIRTAHNLDD
AFEVAYALAPEKVFVAGGGQIYAAAWDRLDVLEITEVDIEPAGEVRFPLIGPEWVVVSREQADGYAFVTLEKDTESILN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dfrA5 AET25387.1 dihydrofolate reductase Not tested PAGI-2(C) Protein 7e-16 42
dfrA5 AFG30110.1 dihydrofolate reductase Not tested PAGI-2 Protein 7e-16 42
dfrA1 ADZ05803.1 trimethoprim-insensitive dihydrofolate reductase Not tested AbaR3 Protein 6e-16 42
unnamed AEL12695.1 DfrA5 Not tested AbaR21 Protein 6e-16 42
dfrI CAJ77029.1 dihydrofolate reductase type I Not tested AbaR1 Protein 1e-15 41
dfrA1 AGF34987.1 DfrA1 dihydrofolate reductase Not tested SGI1 Protein 1e-15 41
dfrA15 AGK07099.1 DfrA15 dihydrofolate reductase Not tested SGI1 Protein 8e-17 41
dfrA1 AAX48777.1 DfrA1 trimethoprim-insensitive dihydrofolate reductase Not tested SGI2 Protein 1e-15 41