Gene Information

Name : hsdM (BCO26_2939)
Accession : YP_004570381.1
Strain : Bacillus coagulans 2-6
Genome accession: NC_015634
Putative virulence/resistance : Unknown
Product : type I restriction-modification system DNA methylase
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0286
EC number : -
Position : 3035352 - 3036872 bp
Length : 1521 bp
Strand : -
Note : PFAM: N6_Mtase; HsdM_N

DNA sequence :
ATGATGGAAACAGCAAAGATTGGATTCGAAGAAACACTTTGGAAATCTGCTGACAAATTACGTGGAAGCATGGATGCATC
CGAATATAAACACGTAGTCTTAGGATTGATTTTCTTAAAATACATTTCTGATAAGTTTGAAATGAAGTATAACGAGTTAG
TTGAAGAAGGAGAAGGTTTTGAAGAAGACCGCGATGAATATACAGCAGAGAATATTTTCTGGGTACCGAAACAGTCACGT
TGGAGCTTCATTAAAGACCGTGCGAAAGACCCGAAAATCGGTCAATATATTGATGAAGCGATGATTGAAATTGAAAAAGA
AAACCCGTCACTCAGAGGTGTGTTAGATAAACGTTATGCCCGCCCTGAGATTGATAAACGCCGATTAGGAGAACTGATAG
ACCTCATTTCAACCATTAAATTGCACAGCAAACAAGAAAAAGACTTACTTGGTCGAGTTTATGAATATTTCTTAGGTAAG
TTTGCCAGTGCAGAAGGAAAAGGCGGTGGCGAGTTCTATACGCCACAAAGTGTTGTTAAAACATTGGTTGAAATGACTGA
ACCTTATGAAGGGCGGATTTATGACCCTTGTTGTGGTAGTGGCGGCATGTTTGTTCAAAGTGAAAAGTTTGTTGAACGCC
ATCAAGGAAAAATTGATAATCTCTCTATTTATGGTCAGGAACTCAATTCAACGACTTGGAAGCTTTGTAAAATGAATCTT
GCTATCCGTGGAATAGAGGGGAATATCGGCGAACATCATGCGGATACGTTCCATAATGATTTACATAAAACGTTGAAAGC
AGATTTCATCCTTGCCAATCCTCCATTCAATGTGAGTGACTGGGGCGGAAATGAATTAGTGGATGATGTTCGTTGGAAAT
TCGGCACACCGCCAGCGAGCAATGCCAATTATGCATGGTTACAGCATATGATTTATCACCTTTCACCAAATGGCGCAGCT
GGTATTGTATTAGCAAATGGTTCGTTAAGTTCCAATACATCGAATGAAGGGGAAATCCGTAAAAACATACTTGAAGCGGA
TTTAGTCGATGCCATTGTTGCTTTGCCTGACAAATTATTCTATTCAACAGGAATACCAGTGAGCTTATGGATTTTAAACC
GTAATAAGAAAAATCATCCTAAATACCGAAGCCGTGAACATGAAATTCTATTTATCGATGCCAGAAACTTAGGAAAAATG
GTTGACCGCCGCCTGCGTGAATTAACAGAAGAAGATATTCAAAAAATTGCAGGAACATACCGAAACTGGCGTAAACCAGA
TGGGAAATATGAAGACATCAAGGGATTCTGTAAATCAGTGACTTTAGAAGATGTCCGTCAAAATGACTATGTCTTAACGC
CCGGACGCTATGTTGGAATAAGTGATGTCGAGGATGATGGTATACCATTTGAAGAAAAAATGGAAACTTTAACTGTAGAA
TTAAGAGGGTTGTTCGATAAATCCCACCAACTAGAAGAAGAAATTAAGAAGAAATTAGGGGGAATTGGTTATGACTTCTA
G

Protein sequence :
MMETAKIGFEETLWKSADKLRGSMDASEYKHVVLGLIFLKYISDKFEMKYNELVEEGEGFEEDRDEYTAENIFWVPKQSR
WSFIKDRAKDPKIGQYIDEAMIEIEKENPSLRGVLDKRYARPEIDKRRLGELIDLISTIKLHSKQEKDLLGRVYEYFLGK
FASAEGKGGGEFYTPQSVVKTLVEMTEPYEGRIYDPCCGSGGMFVQSEKFVERHQGKIDNLSIYGQELNSTTWKLCKMNL
AIRGIEGNIGEHHADTFHNDLHKTLKADFILANPPFNVSDWGGNELVDDVRWKFGTPPASNANYAWLQHMIYHLSPNGAA
GIVLANGSLSSNTSNEGEIRKNILEADLVDAIVALPDKLFYSTGIPVSLWILNRNKKNHPKYRSREHEILFIDARNLGKM
VDRRLRELTEEDIQKIAGTYRNWRKPDGKYEDIKGFCKSVTLEDVRQNDYVLTPGRYVGISDVEDDGIPFEEKMETLTVE
LRGLFDKSHQLEEEIKKKLGGIGYDF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hsdM YP_251979.1 type I restriction-modification system DNA methylase Not tested SCCmec Protein 6e-163 66
hsdM BAH57701.1 type I restriction-modification system DNA methylase Not tested Type-VII SCCmec Protein 2e-163 65
hsdM BAD24842.1 HsdM protein Not tested Type-V SCCmec Protein 7e-161 64
api49 CAF28523.1 putative HsdM-like N-methyl transferase Not tested YAPI Protein 8e-115 47