Gene Information

Name : BCO26_2556 (BCO26_2556)
Accession : YP_004570000.1
Strain : Bacillus coagulans 2-6
Genome accession: NC_015634
Putative virulence/resistance : Resistance
Product : heavy metal translocating P-type ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 2623872 - 2626007 bp
Length : 2136 bp
Strand : -
Note : PFAM: E1-E2_ATPase; Hydrolase; HMA

DNA sequence :
ATGTCTAATCAACAAACCTTACCATCTGAACAAGAAATGAAAACCTATCGCGTTCAAGGATTATCTTGTACAAATTGTGC
AGCCAAATTTGAAAATAACGTGAAAAATTTAGAAGGTGTAAAGGACGCAAAAGTAAATTTTGGAGCATCCAAAATTACAG
TTTATGGTGAAACAACGATTGAAGAATTAGAAAAAGCAGGGGCCTTTGAGAATTTAAAGATTCAGGATGAAAAAGAACAA
AGGATAGAGTATAAGCCTTTTTGGAAGGAAAAAGAAAATATTAAGGTTTATATTTCGGATGCATTGCTCATTATTAGTTG
GTTTCTAGGAAGGCAATTTGGTGAAAATAATATTATCCCTACGATTGGATATGCTGCATCGATTTTAATAGGTGGATATT
CCTTATTTATTGAAGGCCTTAGAAATTTAAGTAAATTTAAATTCGATATGGATACGCTCATGACGATCGCCATAATAGGA
GCCGCGTTGATTGGACAATGGGGTGAAGGAGCAACCGTTGTGATCCTTTTCGCCATTAGCGAAGCCTTAGAGCGTTATTC
AATGGATAAAGCTCGTCAATCGATTGGAATGTTGATGGATATCGCTCCAAAAGAAGCGTTAATTCGCCGTGAAAATGAAG
AAATAATGGTTCACGTGGAGGATATTCAAATCGGTGATATTATGATCGTCAAGCCTGGGCAAAAATTAGCGATGGACGGA
ATAGTTATAAAGGGTACATCCACATTAAATGAGGCTGCTATCACTGGAGAAAGTGTTCCAGTAACCAAAACCATTGATGA
TGAGGTCTATGCTGGCACATTAAATGAAGAAGGATTATTAGAAGTAAAAGTAACCAAACGGGTTGAAGATAACACATTAT
CGAAAATTATTCATTTAGTAGAAGAAGCTCAAGCAGAGAAAGCACCTTCTCAAGCATTTGTTGATAAATTTGCAAAATAT
TACACACCAGCTATCATCATTTTGGCTACATTAATTGCGATTATTCCACCGTTATTATTCGGAGGAGATTGGAGTTACTG
GATATATGAAGGATTAGCTGTATTAGTGGTTGGTTGCCCTTGTGCCTTAGTTGTTTCAACTCCAGTTGCAGTAGTTACTG
CCATAGGAAATGCGGCAAGAAACGGTGTTTTAATTAAAGGTGGGATTCATTTAGAAGAAGCAGGTCACTTAAAGGTTATT
GCTTTTGATAAAACAGGTACACTTACAAAAGGTATTCCAGCGGTTACAGATATTGTGACATTTGGTGGAAATGAAAATGA
GTTGATGACGATTACAGCTGCCATCGAAAAGGGTTCCCAGCATCCACTTGGTACAGCCATTATAAGAAAAGTAGAAGAAA
ATGGATTGAATATTAATGGAGTTTCGGTTGAAGAGTTTCAATCCATTACAGGTAAAGGCGTAAAAGCGAAAGTAAATAAT
GAAATGTATTATGTAGGAAGTCCAACTCTTTTTGAAGAATTGCACGGTAGTATCGAAAACGATAAAAAACAAAAAATTGA
AAAGATGCAAACACAAGGGAAAACGGTGATAGTGTTAGGAACGGAAAAAGAAATTCTTTCGTTTATTGCTGTTGCTGATG
AAATAAGAGAATCATCGAAATCCGTGATCCGTAAACTTCATCAAATTGGAATTGAAAAAACTGTTATGCTTACAGGTGAT
AACAAAAGAACAGCAGAAGTCGTCGGAAAAGAAGTAGGTGTTTCTGATATTAAGGCCGATTTGCTACCAGAAGATAAATT
AAATTTCATTAAAGAACTTCGAGGGAAAAATCAAGGTGTCGCAATGGTCGGTGATGGTGTGAACGATGCACCTGCTCTTG
CAGCTTCAACTGTTGGTGTTGCGATGGGAGGAGCTGGAACCGATACAGCATTAGAAACAGCTGATATTGCGTTAATGTCT
GATGATTTAAGTAAATTGCCATATACCATCAAATTAAGTCGTAAGGCTTTATCTATCATCAAACAAAACATTACATTCTC
TTTAGCAATTAAATTAGTAGCATTGTTGTTAGTAATCCCCGGTTGGTTAACGCTTTGGATAGCGATATTTTCCGATATGG
GAGCAACATTACTTGTAACGCTAAACAGTTTAAGGTTATTGAAGGTTAAAGAATGA

Protein sequence :
MSNQQTLPSEQEMKTYRVQGLSCTNCAAKFENNVKNLEGVKDAKVNFGASKITVYGETTIEELEKAGAFENLKIQDEKEQ
RIEYKPFWKEKENIKVYISDALLIISWFLGRQFGENNIIPTIGYAASILIGGYSLFIEGLRNLSKFKFDMDTLMTIAIIG
AALIGQWGEGATVVILFAISEALERYSMDKARQSIGMLMDIAPKEALIRRENEEIMVHVEDIQIGDIMIVKPGQKLAMDG
IVIKGTSTLNEAAITGESVPVTKTIDDEVYAGTLNEEGLLEVKVTKRVEDNTLSKIIHLVEEAQAEKAPSQAFVDKFAKY
YTPAIIILATLIAIIPPLLFGGDWSYWIYEGLAVLVVGCPCALVVSTPVAVVTAIGNAARNGVLIKGGIHLEEAGHLKVI
AFDKTGTLTKGIPAVTDIVTFGGNENELMTITAAIEKGSQHPLGTAIIRKVEENGLNINGVSVEEFQSITGKGVKAKVNN
EMYYVGSPTLFEELHGSIENDKKQKIEKMQTQGKTVIVLGTEKEILSFIAVADEIRESSKSVIRKLHQIGIEKTVMLTGD
NKRTAEVVGKEVGVSDIKADLLPEDKLNFIKELRGKNQGVAMVGDGVNDAPALAASTVGVAMGGAGTDTALETADIALMS
DDLSKLPYTIKLSRKALSIIKQNITFSLAIKLVALLLVIPGWLTLWIAIFSDMGATLLVTLNSLRLLKVKE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 0.0 65
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 0.0 63
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 0.0 63

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BCO26_2556 YP_004570000.1 heavy metal translocating P-type ATPase BAC0298 Protein 3e-112 46
BCO26_2556 YP_004570000.1 heavy metal translocating P-type ATPase BAC0092 Protein 4e-95 42
BCO26_2556 YP_004570000.1 heavy metal translocating P-type ATPase BAC0124 Protein 2e-91 41