Gene Information

Name : pyk (SGPB_0855)
Accession : YP_004559019.1
Strain : Streptococcus pasteurianus ATCC 43144
Genome accession: NC_015600
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 894897 - 896399 bp
Length : 1503 bp
Strand : +
Note : functional classification: COG0469(G)

DNA sequence :
ATGAATAAACGCGTAAAAATCGTTGCAACACTTGGTCCTGCGGTAGAACTCCGCGGTGGTAAAAAATTCGGCGAAGCTGG
ATATTGGGGTGAAAGCCTTGATGTTGAAGCATCAGCTCAAAAAATCGCTGAATTGATTAAAGAAGGTGCGAACGTCTTCC
GTTTCAACTTCTCACACGGTGACCACGCAGAACAAGGTGACCGTATGGCAACTGTACGTCGTGCAGAAGAAATTGCTGGT
CAAAAAGTTGGTTTCCTTCTTGACACTAAAGGTCCAGAAATCCGTACTGAACTTTTTGAAGGTGACGCTAAAGAGTATTC
ATACAAAACTGGTGAAAAAATCCGTGTTGCTACTAAACAAGGTATCAAATCAACTCGTGAAGTTATTGCATTGAACGTTG
CTGGCGCTCTTGACATCTACGATGATGTTGAAGTTGGTAAACAAGTTCTTGTTGATGATGGTAAACTTGGTCTTCGTGTT
ATTGCTAAAGATGATGCAACTCGTGAATTCGAAGTTGAAGTTGAAAACGATGGTGTCATCGCTAAGCAAAAAGGTGTAAA
CATTCCTTACACTAAAATCCCATTCCCAGCTCTTGCTGATCGTGACAACGCTGATATCCGTTTCGGTCTTGAACAAGGTC
TTAACTTTATCGCTATCTCATTCGTACGTACTGCAAAAGACGTTAACGAAGTTCGTGCTATCTGTGAAGAAACTGGTAAC
GGACACGTTCGTTTGTTTGCTAAAATCGAAAACCAACAAGGTATTGACAACATTGATGAAATCATCGAAGCTGCTGACGG
TATCATGATTGCTCGTGGTGATATGGGTATTGAAGTACCATTCGAAATGGTTCCAGTTTACCAAAAAATGATTATCACTA
AAGTTAATGCAGCTGGTAAAGCAGTTATCACAGCAACTAACATGCTTGAATCAATGACTGACAAACCACGTGCTACTCGT
TCTGAAGTATCTGACGTATTCAACGCTGTTATCGATGGTACTGATGCAACTATGCTTTCAGGTGAATCTGCAAATGGTAA
ATACCCAGTTGAAGCTGTTCGTGCAATGGCTACAATCGATAAAAATGCTCAAACTCTTCTTAACGAATACGGACGTCTTG
ATTCAACATCATTCGCTCGTACTTCTAAAACAGAAGTTGTGGCTTCAGCAGTTAAAGATGCAACAAGCTCAATGGATATT
AAACTTGTCGTAGCTCTTACTGAATCTGGTAACACTGCTCGTCTTATCTCTAAATACCGTCCAGATGCTGACATCTTGGC
TGTAACATTTGACGAAAAAACTCAAAAATCACTTATGATTAACTGGGGTGTTATTCCGGTTGTAACTGAAAAACCTGCAT
CAACTGATGACATGTTTGAAGTTGCTGAAAAAGCTGCCCTTGAATCAGGATTAGTTCAATCAGGTGATAACATCGTTATC
GTCGCTGGTGTTCCAGTTGGTTCAGGTGGTACAAACACAATGCGTATCCGCACTGTAAAATAA

Protein sequence :
MNKRVKIVATLGPAVELRGGKKFGEAGYWGESLDVEASAQKIAELIKEGANVFRFNFSHGDHAEQGDRMATVRRAEEIAG
QKVGFLLDTKGPEIRTELFEGDAKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGKQVLVDDGKLGLRV
IAKDDATREFEVEVENDGVIAKQKGVNIPYTKIPFPALADRDNADIRFGLEQGLNFIAISFVRTAKDVNEVRAICEETGN
GHVRLFAKIENQQGIDNIDEIIEAADGIMIARGDMGIEVPFEMVPVYQKMIITKVNAAGKAVITATNMLESMTDKPRATR
SEVSDVFNAVIDGTDATMLSGESANGKYPVEAVRAMATIDKNAQTLLNEYGRLDSTSFARTSKTEVVASAVKDATSSMDI
KLVVALTESGNTARLISKYRPDADILAVTFDEKTQKSLMINWGVIPVVTEKPASTDDMFEVAEKAALESGLVQSGDNIVI
VAGVPVGSGGTNTMRIRTVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 2e-70 44
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 6e-71 44
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 6e-71 44
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 5e-71 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_004559019.1 pyruvate kinase VFG0479 Protein 3e-71 44