Gene Information

Name : Desru_3588 (Desru_3588)
Accession : YP_004547076.1
Strain : Desulfotomaculum ruminis DSM 2154
Genome accession: NC_015589
Putative virulence/resistance : Unknown
Product : type I site-specific deoxyribonuclease HsdR family
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0610
EC number : -
Position : 3631693 - 3634707 bp
Length : 3015 bp
Strand : +
Note : TIGRFAM: type I site-specific deoxyribonuclease, HsdR family; PFAM: protein of unknown function DUF450; type III restriction protein res subunit; KEGG: mpi:Mpet_1680 type I site-specific deoxyribonuclease; SMART: DEAD-like helicase

DNA sequence :
ATGCCATATACCGAAGCAAATTATGAAAATGCGGTGCTTGAGGTTTTCCGCGACACATTGGGTTACGGCTATTCCTACGG
GCCTGATGTTGTGCGCGATTATTCCGACCCACTGTATACAGACGAGTTGCTGCCTGCCCTGCGGCGCGTCAACTCGAAAC
TCCCGGAAGTTGCACTCTCCGAGGCGGTTTATAAGCTGCGCAATTTCGAAGGTGGCACGGTGTTGCAGAAAAACGTCCAA
TTTATGGACTACCTCCAAAACGGCGTATCAGTGAATTATTATGACAAGGGTGAACAACGTTCCGCACTCGTTCAGCTTGT
GGACTTTGATAACATCAAGCAAAACACTTTCACTGTCGCTAACCAGTGGACTATTACCGAAAACAGTGAGAAACGTCCAG
ATGTTATTGTGTTCCTGAACGGTCTGCCTGTAGTGGTATTCGAGTTAAAGTCACCGAGTCGCGAGGAAACCGATGCTAGC
GAAGCTTATCGCCAGCTTCGTAACTATATGAAAGAGATCCCATCCCTGTTCATCTACAACGCTTTTCTTGTGATGAGCGA
CCTCGCCACTTCCAAAGCGGGTACAATCACCGCCGATGAAGACCGTTTTATGGAATGGAAAACAAAAGACGGCAGTTACG
AAAATACGCAGTACGCCCAGTTCGACACCTTCATTGAAGGAATGTTCGAGAAGGGGCGACTGCTTGATATTATCAAGAAT
TTTATCTGCTTCTCCGGCGACGCGAAGATTCTTGGTGCCTATCACCAATATTTTGCCGTGCGGAAGGCCATTACTTCCAC
CGCCAAGGCAACCGAAACAGACGGGCGTGGCGGTGTTTTTTGGCATACGCAAGGCAGTGGCAAGTCATTGTCTATGGTAT
TCTACGCCCATCTTTTACAGGAGATATTGAACTCCCCTACAATCGTTGTGCTGACCGACCGTAACGACCTTGACGATCAG
CTGTTCGGGCAATTTGCAAAGTGTGCGGACTTCCTGCGCCAAACGCCCCAACAAGCCGAAAGCCGTATTCATTTAAAAGA
GCTTCTCGCGGGGCGGCAAGCGAACGGTATTATCTTCACTACGATGCAAAAGTTTGAGGAATCCTCCGAAGCCCTCTCCG
ACCGACGCAACATCATCGTTATGGCGGACGAGGCGCACCGTGGGCAATATGGACTTGAGGAAAAGGTGGATGCCAAGACA
GGACGTGTTATCCTCGGTACGGCTCGGATTATCCGTGACAGCCTGCCAAATGCGACCTACATAGGATTTACTGGCACCCC
CATCTCCTCGAAAGACCGCTCGACAATTGAGGTTTTCGGCAATTACATTGATATCTACGATATGACTCAAGCTGTGGAGG
ACGGCGCAACTCGCCCGGTCTACTATGAGAGCCGGGTTATTCACTTGAAATTAGACGAGGATGTTTTGCAGCTAATCGAT
GCCGAATACGACATTATGGGTGAGAATGCCGAACCATATGCCATAGAGAAAAGCAAAAAGGAACTTGGGCAGATGGAAAG
CATCCTTGGTGCCGACCAGACGATAACTGCCCTGTGTGAGGACATCGTAAAGCATTATGAGGAAAACCGCCAGTATGAAC
TGACTGGCAAGGCAATGATAGTTGCTTACTCTCGCCCGATTGCTATGAAGATTTACCATAAGATTCTTCAAATGCGTCCA
GATTGGACAGAAAAACTTGGTGTGGTGATGACAAGCGGTAACAACGACCCTGAAGAATGGCGCGAGATCATCGGCAATAA
GCGCCACAAAGACGAAATGGCGAAGAAGTTCAAGGATAATAACAGCCCCCTTAAAATCGCCATTGTGGTGGATATGTGGC
TAACAGGATTCGATGTTCCGAGCCTTGCAACGATGTACGTTTACAAGCCGATGGCGGGTCATAATCTTATGCAGGCAATC
GCACGCGTCAATCGCGTTTATAAGAATAAAGAAGGCGGCTTAGTGGTTGATTATGTTGGTATCGCGTCCGCGCTGAAACA
GGCGATGAACGACTACACCAACCGTGATAAACAGAACTACGGGGAACAGGATATTGCCAAGACCGCCCTCCCGAAGTTTA
TTGAAAAGTTGGAAGTTTGCCGTGACTTGTTCCATGGGTTTGACTACGCCGGCTTTATGGACGCGAAAGCTACAGACCTT
GCCCGCGCCAAGGCAATCAGTGGCGGCGTAAACTTCCTGTCTGGTATAGATAAAGAAAAGCAGCGCGAGTCTTTCGTTAA
AGAGGCTATGCTGCTCCGTCAGGCGTTGTCACTCTGTCGCTCACTCCTTAAGCCTGAACAGCGATTTGAAGCGGCATATT
TTGAAGCAGTTCGGACTCTCCTAACCCGTATTACGGGCGAAGGTAAGCCGCTGTCCCTGAAAGAAATAAATGCCCGCGTC
AACGAACTGTTAAAAGCGAGCATTCAGAGCGAAGGCGTTATAAACCTGTTTTCTGATATAGATACGGGGTTCTCGCTTTT
CGACCCGAAGTTTCTCGAGGAAATCGCTAAGATGAAGGAACGCAACCTCGCGGTAGAAATCCTTAAAAAACTTCTCGCCG
AGCAAGTATCGCTCTACCGTCGAACGAATCTTGTTAAGTCAGAAAAGTTTTCCGAAATGCTATCCCGTGCAATGAAAGCG
TACTTGAACGGGATGCTTTCCAATGAGGAAGTTATTGCCGAACTAATGAAGATGGCAAAGGACATGGCAAACGCTCAAGC
GGAGGGCGACGCGCTTGGACTGAATGATGAAGAGCTGGCATTCTATGATGCTCTGACTCGTCCCGAAGCAGTAAAGGATT
TCTATCAAAATGAAGAACTTGTAGCAATGACTCATGAGCTTACCGATATGCTCCGCAAGAACCGCACTATCGACTGGCAG
AAGAAAGAATCTGCTCGCGCCGGAATGCGACGCATGGTAAAGAAGCTGTTGAAAAAATATAAATACCCGCCTGATGGTAT
GGAAGATGCAATCGCCACCGTAATTGGTCAGTGCGAGATGTGGGCAGATAACTAA

Protein sequence :
MPYTEANYENAVLEVFRDTLGYGYSYGPDVVRDYSDPLYTDELLPALRRVNSKLPEVALSEAVYKLRNFEGGTVLQKNVQ
FMDYLQNGVSVNYYDKGEQRSALVQLVDFDNIKQNTFTVANQWTITENSEKRPDVIVFLNGLPVVVFELKSPSREETDAS
EAYRQLRNYMKEIPSLFIYNAFLVMSDLATSKAGTITADEDRFMEWKTKDGSYENTQYAQFDTFIEGMFEKGRLLDIIKN
FICFSGDAKILGAYHQYFAVRKAITSTAKATETDGRGGVFWHTQGSGKSLSMVFYAHLLQEILNSPTIVVLTDRNDLDDQ
LFGQFAKCADFLRQTPQQAESRIHLKELLAGRQANGIIFTTMQKFEESSEALSDRRNIIVMADEAHRGQYGLEEKVDAKT
GRVILGTARIIRDSLPNATYIGFTGTPISSKDRSTIEVFGNYIDIYDMTQAVEDGATRPVYYESRVIHLKLDEDVLQLID
AEYDIMGENAEPYAIEKSKKELGQMESILGADQTITALCEDIVKHYEENRQYELTGKAMIVAYSRPIAMKIYHKILQMRP
DWTEKLGVVMTSGNNDPEEWREIIGNKRHKDEMAKKFKDNNSPLKIAIVVDMWLTGFDVPSLATMYVYKPMAGHNLMQAI
ARVNRVYKNKEGGLVVDYVGIASALKQAMNDYTNRDKQNYGEQDIAKTALPKFIEKLEVCRDLFHGFDYAGFMDAKATDL
ARAKAISGGVNFLSGIDKEKQRESFVKEAMLLRQALSLCRSLLKPEQRFEAAYFEAVRTLLTRITGEGKPLSLKEINARV
NELLKASIQSEGVINLFSDIDTGFSLFDPKFLEEIAKMKERNLAVEILKKLLAEQVSLYRRTNLVKSEKFSEMLSRAMKA
YLNGMLSNEEVIAELMKMAKDMANAQAEGDALGLNDEELAFYDALTRPEAVKDFYQNEELVAMTHELTDMLRKNRTIDWQ
KKESARAGMRRMVKKLLKKYKYPPDGMEDAIATVIGQCEMWADN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hsdR BAH57699.1 type I restriction-modification system endonuclease homologue Not tested Type-VII SCCmec Protein 0.0 42
hsdR BAD24840.1 type I restriction-modification system endonuclease homologue Not tested Type-V SCCmec Protein 0.0 42
hsdR YP_251977.1 type I restriction-modification system restriction subunit Not tested SCCmec Protein 0.0 42
api52 CAF28526.1 hsdr-like Type I restriction enzyme Not tested YAPI Protein 3e-167 42