Gene Information

Name : Desru_3582 (Desru_3582)
Accession : YP_004547071.1
Strain : Desulfotomaculum ruminis DSM 2154
Genome accession: NC_015589
Putative virulence/resistance : Unknown
Product : adenine-specific DNA-methyltransferase
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0286
EC number : -
Position : 3625814 - 3627355 bp
Length : 1542 bp
Strand : +
Note : KEGG: pmz:HMPREF0659_A6123 putative type I restriction-modification system, M subunit; PFAM: N-6 DNA methylase

DNA sequence :
ATGGCAAACGGGAATAACACAGCCGATATCGGTTTCGAACAACAAATCTGGGCGGCAGCAGACATTTTGCGCGGAAATAT
GGATGCCGCCGAGTATAAGCACGTGGTCCTGGGGCTTATCTTCCTAAAGTACATATCGGACAAGTTCGAGGAGCGCTATC
AGGAACTCCTCGCTGATGATGACGATGTGGAGGATAAGGATGCTTACACTGAAGCGAACATCTTTTACGTACCGCCTATC
GCACGGTGGAGTGTGATTGCTGAATGGGCACACAAAACCGGAAAAATAACAGATGAAAACGGCAAGGAAGAGTTTTTCGA
CATTGGCGGTATAATTGACCGCGCTATGAGAGCTATTGAAAAGGAAAACAAACGGCTTAAGGATGTTCTCCCTAAGAACT
ATGCCCGTAGCGAACTTGATAAGCGCCGACTCGGGAATGTGGTTGATTTATTTACCAACATACAGATGATTGAGCACGGC
ACGGATAAGGACATCCTTGGTCGTACCTATGAATATTGCCTCGCCAAATTCGCTGAGCAAGAAGGCAAACGCGCGGGTGA
ATTCTATACGCCGTCCTGCGTTGTTCGGACGCTTGTTGAGGTGTTGAAGCCCTTCAAAGGGCGAGTGTACGACCCCTGCT
GCGGTTCGGGCGGAATGTTCGTGCAATCCGCAGACTTCGTAAGTCACCATGCCGGCAATATCAACAATTTATCTATTTTC
GGACAAGATGCGAACCCGACAACACGCAAAATGGCATTAATGAACCTTGCTATTCGCGGCATCGAAGCTGACCTGGGCGG
GTATAACGCTGATACTTTTCATAATGACTTGCACCCCACGCTGAAAGCGGACTTTATACTTGCCAATCCGCCGTTCAATC
TTTCGGACTGGAATGACGGATCGTTAAACGATGACCCGCGCTGGAAGTACGGCTTACCGCCATCGGGCAATGCCAACTTT
GCGTGGCTTCAACATATGATTTACCACCTTTCACCAAACGGCAAAATTGGTATGGTGCTTGCCAACGGCTCGCTGTCCTC
TCAAAGCGGAGGAGAGGGTGATATTCGTCGCAAAATTGTAGAGGATGATCTCGTAGAGGGAATTGTCGCGATGCCGACGC
AGCTCTTCTACACCACGCAGATTCCAGTTTCGCTATGGTTTATCAATCGTAACAAGAAACAGAAGGGCAAGACATTATTT
GTTGACGCCCGCAAGATGGGGACGATGGTTAATCGCCGCTTGCGCGAGATGACTACCGAGGACATTGCCAAAATAGCTGC
TACTTTCGAGGCGTTTGACAACGGGACGCTGGAGGATGTGAAGGGCTATTGCGCCGCTGTAACGACCGCTGATATCGCAA
AGCAGGACTACATACTTACACCAGGGCGCTATGTTGGAATTGAGGAGCAAGAGGACGACGGCGAACCCTTTGATGAGAAA
ATGGCTCGGCTGACAAGCGAACTATCCGAAATGTTCAAACGCTCTCATGAATTGGAGGACGAAATACGCAAAAGACTGGG
GGCAATTGGATATGACATCTAA

Protein sequence :
MANGNNTADIGFEQQIWAAADILRGNMDAAEYKHVVLGLIFLKYISDKFEERYQELLADDDDVEDKDAYTEANIFYVPPI
ARWSVIAEWAHKTGKITDENGKEEFFDIGGIIDRAMRAIEKENKRLKDVLPKNYARSELDKRRLGNVVDLFTNIQMIEHG
TDKDILGRTYEYCLAKFAEQEGKRAGEFYTPSCVVRTLVEVLKPFKGRVYDPCCGSGGMFVQSADFVSHHAGNINNLSIF
GQDANPTTRKMALMNLAIRGIEADLGGYNADTFHNDLHPTLKADFILANPPFNLSDWNDGSLNDDPRWKYGLPPSGNANF
AWLQHMIYHLSPNGKIGMVLANGSLSSQSGGEGDIRRKIVEDDLVEGIVAMPTQLFYTTQIPVSLWFINRNKKQKGKTLF
VDARKMGTMVNRRLREMTTEDIAKIAATFEAFDNGTLEDVKGYCAAVTTADIAKQDYILTPGRYVGIEEQEDDGEPFDEK
MARLTSELSEMFKRSHELEDEIRKRLGAIGYDI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hsdM YP_251979.1 type I restriction-modification system DNA methylase Not tested SCCmec Protein 4e-140 57
hsdM BAH57701.1 type I restriction-modification system DNA methylase Not tested Type-VII SCCmec Protein 8e-141 57
hsdM BAD24842.1 HsdM protein Not tested Type-V SCCmec Protein 1e-139 56
api49 CAF28523.1 putative HsdM-like N-methyl transferase Not tested YAPI Protein 2e-108 46