Gene Information

Name : Desru_2499 (Desru_2499)
Accession : YP_004546016.1
Strain : Desulfotomaculum ruminis DSM 2154
Genome accession: NC_015589
Putative virulence/resistance : Unknown
Product : DNA polymerase I
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0749
EC number : -
Position : 2544706 - 2547342 bp
Length : 2637 bp
Strand : +
Note : TIGRFAM: DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease, N-terminal resolvase-like domain; 5'-3' exonuclease, SAM-fold domain; 3'-5' exonuclease; KEGG: drm:Dred_1599 DNA polymerase I; SMART: 5'-3' exonuclease; Helix-hairpin-helix d

DNA sequence :
TTGTCCCTGGATATCCTCTTGGTTATAGACGGAAATAGTTTGATACACCGGGCTTTTCATGCCCTCCCCCTGTTAAGCAA
CAGCAAAGGCGTTTTTACCAATGCCGCTTACGGGTTTACCACCATGCTGATGAAAGTACTAAATGAAGAGCAGCCGGGTC
TGGTTACCGTGGCCTTTGATAAAGGAAAGAAAACCTTTCGTAATGAACAGTATGCTGATTACAAAGGAACCCGTAAAGCT
ACGCCCGATGAGCTTAGACCCCAATTTTTGCTGGTCAAGGATATTCTGAAGGCCATGCGTATTCCTTATTTTGAGTTGGA
AGGTTATGAGGCCGACGATTTAATCGGCACCATTACCACCCAGGGAGAATCCATGGGTCTCAATATACGGATTTTGACCG
GTGACCGGGACGCCTTGCAACTGGTGTCACCGAAAACCAAAGTTATGCTGACACGCAAGGGAATTACTGAAATCGAACTG
TTTGATGAGGGAAAGGTCTGGGACCGGTTCGGCATTCATCCCCATCAGATCATTGATTTAAAAGCCCTGCAGGGAGATAC
TTCGGACAATATTCCCGGTGTTCCGGGCATCGGTGAGAAAACTGCCGCTGTTCTGATCAAGGAATATGGTCAAGTGGAGG
AGGTTATTCGCAATCTGGATCACCTGTCTCCCAGGCATCAAAAATTGCTCCGGGGCCATGAGGACCAAGCCCTGCTTTCC
AAAAGCCTGGCCACCATCGTAAAAGATGTGCCCATGGAAATTGATTTATCCCAATGCTCCTGGCGTGGTCCGGACTATCC
GAAGCTTTTGGATGTTTTCAATGATTTGGAGTTTAAAACTCTCATTAAGCAGATTATTGAGGGTTCAAGAAAATCAAAAA
AATCCAAAGAAGCCAAAAGCGATCTGCCCCCTGTAAAAACTTACCGGGTAGGCTACCAAACCATTACCGACCCCCGGGAG
CTACCGGACATCTTAACCAAGATTAACAAAGCCGGTCAGGTGGCTTTATCTCTTGAAGGTTCCCGCAACCAGGGCGTCAC
TGGAATGGCCCTGGCCTTTGACGATTCCGAGGTGCTGTTGCTGCCATCGGAAGCCATGGATGCTTTGGGGCTGGAACTGC
TGCAATCCCTGTGTGAAGACCCCCAGATTAAAAAATATTTTCATAACGCCAAAAATGCCATCTGGTTATTGCACCGGCAG
GGCATAACCCTTAGAAATTTGGCCGGCGACACCATGGTGGCGGCTTATCTGCTGAATCCCACCGCTGCCAATTATGACCT
GACGGATATTGCCCTGGAACACCTGGGCATTGTGTTGCCCGTGGAGGGGACCATGGCCTGGGCGGCCGCAGCCGACGCCA
TCCTTCGCCTGGCCCCGGCTCTGCACCAAAAGCTCCAGGCCCGGGAAGAGGACCGCCTTTATGAAGAGGTGGAACTCCCT
TTGATTTCCGTTCTGGCCAATATGGAAATAGCAGGCATCACCGTGGATCAGCAGCAATTAAAGGAAATTTCTGCCGAACT
GCAGGAAGCCATCGAAGCACTGGCAACACTGATTCACCACCTGGCCGGCGAGGAATTCAACATTAACTCCACCCGGCAGT
TGGGACAGATTTTATTTGATAAATTAAAACTGCCTGTTTATAAAAAAACCAAAACAGGCTATTCAACGGATGCGGAGGTC
CTTGAAAAACTGGCTGAAGAGCATGAGATTGTTTCCGTTCTGCTGGAGTACCGCCAGTTAACAAAACTAAAATCCACCTA
TGCCGACGGTCTGGCGGCATTGGTTGATCCGCAAACCAAAAGGCTGCACTCGACCTTCCACCAGACTGTAACGGCCACCG
GCAGACTCTCCAGTGCGGAACCTAACTTGCAAAACATCCCCATCCGTTTGGAGTCCGGCAGGCGCATTCGGAAGGTTTTT
GTTCCCCGCCAAAGGGGCAATTTAATTCTGACGGCGGACTACTCTCAAATTGAATTAAGAATTTTAGCTCACGTTTCCCA
GGACGCCAGTTTCCTGGACGCCTTCCGGCAGGGCCAGGATATACACACCCGGACGGCGTCCGAAGTTTTCGGCGTGTCCA
TGGATGAGGTTACGCCACAGTTGCGCGGCCGGGCCAAGGCGGTAAATTTCGGCATTGTTTATGGCATCAGTGATTTCGGC
TTAGCCAGGGACTTGAGAGTGAGCCGGAAGGAAGCCAAGAGTTACATTGACAGTTATTTCGCCCGCTGTCCCGGTATACA
AAACTACATCCACCGGGTTATTCAGGAGGCCAAAGAACAGGGTTATGTAACCACCCTGTTAAACCGCCGCCGTTACCTGC
CGGAATTGTTTAGCTCCAACTACAATATCCGGAGTTTTGGGGAGCGCGCCGCCATGAACACGCCCATCCAGGGGACTGCC
GCGGACATTATTAAAATGGCCATGGTGAGAGTGCACCAGGAATTGCGGGAACAGGATTTAAAGGCTAAAATGGTTTTGCA
GGTTCATGATGAATTGATTTTTGATGTCCCGGAGCAGGAAGTGGAAAAGCTTGCGGCTTTGGTTCGGCAATATATGGAAA
GTGCTTTGCAAATGGATGTTCCCCTGGTGGTGGATATTAAAATAGGACCCAACTGGTACGATAAGAGACCTCTTTAA

Protein sequence :
MSLDILLVIDGNSLIHRAFHALPLLSNSKGVFTNAAYGFTTMLMKVLNEEQPGLVTVAFDKGKKTFRNEQYADYKGTRKA
TPDELRPQFLLVKDILKAMRIPYFELEGYEADDLIGTITTQGESMGLNIRILTGDRDALQLVSPKTKVMLTRKGITEIEL
FDEGKVWDRFGIHPHQIIDLKALQGDTSDNIPGVPGIGEKTAAVLIKEYGQVEEVIRNLDHLSPRHQKLLRGHEDQALLS
KSLATIVKDVPMEIDLSQCSWRGPDYPKLLDVFNDLEFKTLIKQIIEGSRKSKKSKEAKSDLPPVKTYRVGYQTITDPRE
LPDILTKINKAGQVALSLEGSRNQGVTGMALAFDDSEVLLLPSEAMDALGLELLQSLCEDPQIKKYFHNAKNAIWLLHRQ
GITLRNLAGDTMVAAYLLNPTAANYDLTDIALEHLGIVLPVEGTMAWAAAADAILRLAPALHQKLQAREEDRLYEEVELP
LISVLANMEIAGITVDQQQLKEISAELQEAIEALATLIHHLAGEEFNINSTRQLGQILFDKLKLPVYKKTKTGYSTDAEV
LEKLAEEHEIVSVLLEYRQLTKLKSTYADGLAALVDPQTKRLHSTFHQTVTATGRLSSAEPNLQNIPIRLESGRRIRKVF
VPRQRGNLILTADYSQIELRILAHVSQDASFLDAFRQGQDIHTRTASEVFGVSMDEVTPQLRGRAKAVNFGIVYGISDFG
LARDLRVSRKEAKSYIDSYFARCPGIQNYIHRVIQEAKEQGYVTTLLNRRRYLPELFSSNYNIRSFGERAAMNTPIQGTA
ADIIKMAMVRVHQELREQDLKAKMVLQVHDELIFDVPEQEVEKLAALVRQYMESALQMDVPLVVDIKIGPNWYDKRPL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
polA YP_281523.1 DNA polymerase I Not tested Not named Protein 2e-159 43