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Name : Desru_2185 (Desru_2185) Accession : YP_004545720.1 Strain : Desulfotomaculum ruminis DSM 2154 Genome accession: NC_015589 Putative virulence/resistance : Resistance Product : heavy metal translocating P-type ATPase Function : - COG functional category : P : Inorganic ion transport and metabolism COG ID : COG2217 EC number : - Position : 2206086 - 2208704 bp Length : 2619 bp Strand : - Note : KEGG: drm:Dred_1527 heavy metal translocating P-type ATPase; TIGRFAM: heavy metal translocating P-type ATPase; cadmium-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; DNA sequence : GTGCAAGGAATCCATAACCATAATCAAAAAACGCACGGCGGATGTGGCTGCGGCAATTGCTCCCATACCGCAGAAGAAAA TGCGGAGGTAAAGGATGCGCAGATGGCCCATTCCGGCGAGGGAGTACTGCCTGATAAAAAGCGAAATCCTTTATCCGGTG TTACATTAGGGAAGATAGATTATAGTACGGCCCTGACCAGAGAGTCCCATAGCATGCCCCAAAAACCGGAGGCCCTTTTG GAGCAAAGACAGCAGGGGCAAAAGAGCCGGTTCCGCATAAGCGGCCTGGACTGTGCCGATTGCGCCGCTAAATTGGAGAA AAGAATCAAGGCCCTGCCCGGTGTGACAGAAGCCAGTATTAACTTCGGAGCGGGTAAAATGACCGTCAGCCACACCTCGG CTCTGTCATCCATCTTGGAGGCCGTGAAGGCCGCCGGCTACCAGGCTCACTTAGAGGGAGGACAAAAAACCACGGTTTTC CGGATAAGCGGGATGGACTGCGCCGATTGCGCCGCCAAGCTGGAAAAAAAGCTCCAGGTATTAAGCGGTGTGACGGAAGC AAAAATTAACTTTGGGGCAGGAAAATTGACAGCGAAGCACACAGCCTCGACAGAAACCATTTTGAAGGCCATCGAGAATG CCGGTTTTCAAGGCCGGTTGGCTAACGAAGAAAGGAAGCCGGTGACGAAAAGTTTCTTCGCAGAGATCAAGATGATTCTA ACGGTTCTGTCGGGCTTATTGGTTGGGGCAGGCTTTATCCTTTCTTATCTTAACATGCCGGATTTCATGGTAACGGCGGT TTATCTTGCCGCTATGATCAGCGGAGGGTTTTACACAGCCAGGAGCGGTTTGTATTCCCTCAAGTCATTGTCCTTGGATA TGAATTTCCTGATGATGGTGGCGGCCATCGGCGCGGCAGCCATCGGGGAATGGGCGGAAGGAGCCACGGTGGTATTCCTG TTTGCCCTGGGCAATACTCTGCAGGCTTATACCATGGATAAAACCCGCAACTCCATCCGGGCGCTGATGGATCTCTCCCC CAAAGAGGCTTTGGCACGGCGCAACGGTCAAGAGGTACACCTGCCGGTGGAGGAATTGGTGGTGGGGGACATCATCATTG TGAAACCCGGTGAGCGCATCCCTATGGACGGTGAAGTGCTGGCAGGACGAACCGATGTAAATCAATCCTCCATCACCGGG GAGTCCATGCCGGTGGAGAAAACTGTTGGCCATGAGGTTTATGCCGGTACCATCAACGGTCAGGGGTCCATAGAAGTTAA AGTCACCAAATTGGTAAAAGACACCACTCTGGCTAAAATCATTAATCTGGTGGAAGAGGCCCAGGCCCAGAAGGCGCCGT CCCAGCAGTTTGTGGATGTGTTTGCCGGATACTACACACCGGCGGTGATTGTCACTGCCGTCCTGGTGGCCTTGCTGCCC TGGCTTCTTTTCGGACAACCGTTTCAGCCTTGGTTTGAGCGGGCGCTGATTCTGCTGGTGGTTTCCTGCCCCTGCGCCCT GGTGATTTCCACCCCGGTGTCCATTGTAGCCGCCATTGGCAGCGCCGCCAAAAAAGGCGTGTTAATCAAAGGCGGGGCCT ATCTGGAAGAGGCCGGAGCTTTAAAAGTAATTGCCTTTGACAAGACCGGTACACTGACCGACGGCAGGCCGGAAGTGAAC GCCGTCATTCCTGTTGGCAGCTTTGACTCTCAACAGGTAATGGAAATTGCCGCGGCTATTGAAAACCGCTCCCAGCACCC GCTGGCGGAAGCCATTTTAAGATATGCCCGGCAAGAGAACATCCCGGTGCCGGAAGGCACGGATTTTCAATCCTTCACCG GCAAGGGCGCCGCATTGCGGTTAAAGGGTGAACAGTACTACATCGGCAACAGCCGGTTATTTGAAGAGATAAAGGTATCC CTAAACTATCTGCAAGAACAGATTACGGCATTGCAGCAACAGGGTCAGACCGTAATGATTTTGGGCAGCGGCCAAGAGGC TTTGGGTCTTATTGCGGTGGCGGATAAAATCAGGGAGAGCAGCCGGGCCGCAGTGGCGGGAATGTACCGGGCGGGCATTG CCAAATTGGTGATGCTAACCGGGGATAATGCCGGAACCGCCCGGGTGATTGCCGGGGAACTGGGCATTGACGATTTTCGA GCCGAATTGCTTCCTGAGCATAAGCTGACAGCCATTCAACAATTGCAGAAGGAGAGCGGTAAGGTAGCCATGGTTGGAGA CGGAGTCAATGACGCGCCGGCTTTGGCCACTGCCACTGTGGGCATTGCCATGGGCGGAGCCGGTACGGATACCGCCCTGG AAACCGCAGACATTGTACTCATGGCGGACGACCTGACCAAATTACCCTATGCCATGCACTTGAGCCGCCGGGCTCTGAGC ATTATTAAACAAAACATCGGCTTCTCCCTGCTGGTAAAGGCTGTCTTCCTGGTGGCCACTTTCCTGGGAATGGCCAATTT GTGGATGGCGGTTTTTGCGGATACCGGCACCGCCCTGCTGGTAATTGCCAACGGTATGAGGTTGATGAAGGTGGGAGATC CCTATACTGAGACGACTGTCCGGCCAAAGCAATCCACTGTAGCCTGCCCCAGCCTATAG Protein sequence : MQGIHNHNQKTHGGCGCGNCSHTAEENAEVKDAQMAHSGEGVLPDKKRNPLSGVTLGKIDYSTALTRESHSMPQKPEALL EQRQQGQKSRFRISGLDCADCAAKLEKRIKALPGVTEASINFGAGKMTVSHTSALSSILEAVKAAGYQAHLEGGQKTTVF RISGMDCADCAAKLEKKLQVLSGVTEAKINFGAGKLTAKHTASTETILKAIENAGFQGRLANEERKPVTKSFFAEIKMIL TVLSGLLVGAGFILSYLNMPDFMVTAVYLAAMISGGFYTARSGLYSLKSLSLDMNFLMMVAAIGAAAIGEWAEGATVVFL FALGNTLQAYTMDKTRNSIRALMDLSPKEALARRNGQEVHLPVEELVVGDIIIVKPGERIPMDGEVLAGRTDVNQSSITG ESMPVEKTVGHEVYAGTINGQGSIEVKVTKLVKDTTLAKIINLVEEAQAQKAPSQQFVDVFAGYYTPAVIVTAVLVALLP WLLFGQPFQPWFERALILLVVSCPCALVISTPVSIVAAIGSAAKKGVLIKGGAYLEEAGALKVIAFDKTGTLTDGRPEVN AVIPVGSFDSQQVMEIAAAIENRSQHPLAEAILRYARQENIPVPEGTDFQSFTGKGAALRLKGEQYYIGNSRLFEEIKVS LNYLQEQITALQQQGQTVMILGSGQEALGLIAVADKIRESSRAAVAGMYRAGIAKLVMLTGDNAGTARVIAGELGIDDFR AELLPEHKLTAIQQLQKESGKVAMVGDGVNDAPALATATVGIAMGGAGTDTALETADIVLMADDLTKLPYAMHLSRRALS IIKQNIGFSLLVKAVFLVATFLGMANLWMAVFADTGTALLVIANGMRLMKVGDPYTETTVRPKQSTVACPSL |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| unnamed | BAB47609.1 | cadmium resistance protein B | Not tested | Type-III SCCmec | Protein | 4e-167 | 48 |
| cadA | BAC57487.1 | Probable cadmium-transporting ATPase (Cadmium efflux ATPase) | Not tested | Type-IIIinv SCCmec | Protein | 4e-167 | 48 |
| SE0075 | NP_763630.1 | cadmium resistance protein B | Not tested | SCCpbp4 | Protein | 1e-163 | 47 |
| ORF C97 | AAN62190.1 | putative metal-transporting P-type ATPase | Not tested | PAGI-2(C) | Protein | 3e-134 | 44 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| Desru_2185 | YP_004545720.1 | heavy metal translocating P-type ATPase | BAC0124 | Protein | 4e-107 | 44 |
| Desru_2185 | YP_004545720.1 | heavy metal translocating P-type ATPase | BAC0298 | Protein | 5e-128 | 43 |
| Desru_2185 | YP_004545720.1 | heavy metal translocating P-type ATPase | BAC0100 | Protein | 9e-72 | 41 |
