Gene Information

Name : Desru_1355 (Desru_1355)
Accession : YP_004544914.1
Strain : Desulfotomaculum ruminis DSM 2154
Genome accession: NC_015589
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 1374109 - 1375860 bp
Length : 1752 bp
Strand : +
Note : KEGG: drm:Dred_2312 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region

DNA sequence :
ATGAGACGTACCAAAATTGTATGTACCATAGGACCTGCCAGTGAAAGTTTCGAGGTTTTGAAAGAAATGATGCTGGCAGG
CATGAATGTGGCCAGACTGAATTTTTCTCATGGCACCCACGAAGATCACGGCCGACGCCTGGAGGCTATCCGGCAGGCTG
CCCGGGAAGTGGGTAAAAATATTGCCATTTTGCTGGATACCAAGGGGCCGGAAATTCGATTAAAGAAATTTGCCAATCCC
CCGGTACTCCTTAAACCCGGCCAGTCTTTTACCCTTACCACCCGGGAAGTGCTGGGAGACGACACCATTGTATCGGTAAC
TTACATGGATCTGCCCAAGGATGTCCGGCCGGGCAGCCGGGTGGCGGTGGCCGACGGTCTCATTGAGATGGAAGTGGAAG
CCGTTGAAGGCCAGGATGTTCATTGCCGGGTGATCAATGGCGGTCCCCTTTCCAACCAGAAGGGTGTTAATCTGCCCGGT
GTGAATGTCAATTTGCCTTCCATCACCGAAAGAGATGTGGAGGATATTCGGTTTGGTATCCAGCAGGGTGTGGATTTTAT
TGCCGCCTCTTTTATCCGCAAGGCTTCCGATGTTTTGGCCATCCGGCAGATTGTTGAAGAGGTGGGGGCCGACGTAGCCA
TTATTGCCAAGATCGAAAGCCGCCAGGGTGTGGACAATCTGGCTGAAATTATTAATGTATCCGATGGCATTATGGTGGCC
CGGGGAGATCTGGGAGTGGAAATTCCCGCCGAGGAAGTTCCTGTTTTGCAAAAAACCATGATTCAAAGCTGCAACATTGC
GGGAAAACCAGTGATCACGGCAACCCAGATGCTGGAATCCATGACCCAAAATCCCAGACCCACCCGGGCCGAGGCCAGCG
ACGTAGCCAATGCCATTTTTGACGGCAGCGACGCCATTATGCTGTCCGGGGAGACCGCGGCGGGCAAATACCCGGTGCAG
GCGGTAGAAACCATGGCCCGCATTGCCCAACGGGCCGAGCAGGCGGTGAACTTTGATGCTCTGCTGGAAACCCGCGGATC
CGCTCTGCAGAGAACGGTGACCGACGGCATCAGCCATGCGGTCTGCACCATTGCCAAGGAACTGGGAGTCAGCGCCATTA
TCACAGCCACCGCCAGTGGTCATACAGCCCGTATGATCGCCAAATACCGGCCCAAGGTACCGATTATTGCCGTAACGCCC
AAGGCTGACGTGCTCCGTAAACTGGCCCTGGCCTGGGGTGTAGAACCCTTGTTAATTGGTCCCCTAACCGGCACCGACGA
AATGATCAGTGCCTCGGTGGAAGTATCCCTGACCGCGGGGTTAATCTCCGCCGGAGATCTGGTGGTGATTACTGCCGGTG
TTCCCGTGGGGGTTCATGGGACCACCAACATGATGAAGGTGCATACGGTAGGTACCTTGTTGGCCCGGGGCACAGGGATC
GGTCAGCGGGCCGCCACCGGTTCTGTTCGGATTTGTGCTTCCGGGCAGGAAGCCCTGGAAAAAGTTCGGCCGGGAGATAT
TCTGGTGACCGCCGCTACGGATCGCGAGTTTATTCCGGCTATGGAAAAGGCTGCCGCTGTCATTACCGAAGAAGGAGGCT
TAACCTCCCATGCGGCCATTGTTGGTTTGGAATTTGGCATTCCCGTTGTTGTGGGGGTGGATCAGGCCACCGGCATTTTG
CCGGACGGGGAAATCATTACGGTGGACGGTCAGCGGGGCTTGATTTACGGCGGTACGGCCAGGGTGCTCTAA

Protein sequence :
MRRTKIVCTIGPASESFEVLKEMMLAGMNVARLNFSHGTHEDHGRRLEAIRQAAREVGKNIAILLDTKGPEIRLKKFANP
PVLLKPGQSFTLTTREVLGDDTIVSVTYMDLPKDVRPGSRVAVADGLIEMEVEAVEGQDVHCRVINGGPLSNQKGVNLPG
VNVNLPSITERDVEDIRFGIQQGVDFIAASFIRKASDVLAIRQIVEEVGADVAIIAKIESRQGVDNLAEIINVSDGIMVA
RGDLGVEIPAEEVPVLQKTMIQSCNIAGKPVITATQMLESMTQNPRPTRAEASDVANAIFDGSDAIMLSGETAAGKYPVQ
AVETMARIAQRAEQAVNFDALLETRGSALQRTVTDGISHAVCTIAKELGVSAIITATASGHTARMIAKYRPKVPIIAVTP
KADVLRKLALAWGVEPLLIGPLTGTDEMISASVEVSLTAGLISAGDLVVITAGVPVGVHGTTNMMKVHTVGTLLARGTGI
GQRAATGSVRICASGQEALEKVRPGDILVTAATDREFIPAMEKAAAVITEEGGLTSHAAIVGLEFGIPVVVGVDQATGIL
PDGEIITVDGQRGLIYGGTARVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 6e-106 50
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 3e-106 50
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 3e-106 50
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 9e-106 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Desru_1355 YP_004544914.1 pyruvate kinase VFG0479 Protein 1e-106 50