Gene Information

Name : Isova_0621 (Isova_0621)
Accession : YP_004541302.1
Strain : Isoptericola variabilis 225
Genome accession: NC_015588
Putative virulence/resistance : Unknown
Product : phosphomethylpyrimidine synthase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 667527 - 669254 bp
Length : 1728 bp
Strand : +
Note : TIGRFAM: Thiamine biosynthesis protein ThiC; HAMAP: Thiamine biosynthesis protein ThiC; KEGG: xce:Xcel_1454 thiamine biosynthesis protein ThiC; PFAM: Thiamine biosynthesis protein ThiC

DNA sequence :
ATGTCGCATCTTGCGCAGTCGCGAGCGCTCGCCTTCGAGCGAGACGACGAGTCCGGGATCTGCGTCCCGGTCACCGAGAT
CAGCCTGGCGCCGTCGCCCGACGGCACCCCCAACCCGCCCGTGCGCGTCTACCGGACCGAGGGTCTGGGCGGCGACCCGA
CGCGCGGGCTCCCGCCGCAGCGGTCCGCATGGATCGAGGCGCGCGGGGACACCGAGGTCTACGAGGGTCGCCCGCACGAC
CTCGCCGACGACGGGCGGGGCGCCCGGCGTCGGGGCGCGGCGTCGGCGGAGTGGCGCGGCGAGCGCCGGCCGCCGCGGCG
CGCCGTCCCCGGGCGCACCGTCACCCAGATGCACTACGCCCGCCGCGGCGAGGTCACGCCCGAGATGCGGTTCGTCGCGC
TGCGCGAGGGCGTCGACGTCGAGCTCGTCCGCAGCGAGGTCGCGGCCGGGCGGGCGATCATTCCCGCCAACGTCAACCAC
CCCGAGTCCGAGCCCATGATCATCGGGCGGGCGTTCACCGTGAAGGTCAACGCCAACATCGGCAACTCGGCCGTGCACTC
GTCGATCGCCGAGGAGGTGGAGAAGCTCCAGTGGGCCACCCGCTGGGGCGCCGACACGGTCATGGACCTGTCGACGGGCG
ACGACATCCACACCACGCGCGAGTGGATCCTGCGCAACTCGCCCGTGCCGATCGGCACGGTGCCGGTCTACCAGGCACTC
GAGAAGGTCGACGGCGACGCGTCCCGGCTGAGCTGGGAGGTCTACCGCGACACGGTCATCGAGCAGTGCGAGCAGGGCGT
CGACTACATGACCGTCCACGCGGGCGTGCTCCTGCGGTACGTGCCGCTCACGGCGAACCGCGTGACCGGCATCGTCTCGC
GCGGCGGCTCGATCATGGCCGGCTGGTGCCTCGCTCACCACGAGGAGAACTTCCTCTACACGCACTTCGACGAGCTGTGC
GAGATCTTCGCGCGGTACGACGTCGCGTTCTCGCTCGGCGACGGCCTGCGGCCCGGCTCGCTCGCCGACGCGAACGACGC
CGCGCAGTTCGCCGAGCTCGACACGCTGGCCGAGCTGACGAAGCGGGCGTGGGAGCACGACGTGCAGGTCATGGTCGAGG
GCCCGGGCCACGTGCCGCTGCACCTCGTGCGCGAGAACGTCGAGCGCCAGCAGGAGCTGTGCGACGGCGCCCCGTTCTAC
ACGCTCGGGCCGCTCGTGACCGACATCGCCCCCGGCTACGACCACATCACCTCCGCGATCGGCGCGACCGAGATCGCCCG
GTACGGCACGGCGATGCTGTGCTACGTCACGCCCAAGGAGCACCTGGGCCTGCCGAACCGCGACGACGTGCGCACCGGCG
TCGTGACGTACAAGATCGCCGCGCACGCGGCCGACGTCGCGAAGGGCCACCCGGGCGCGCGCGACCGGGACGACGCGCTG
TCCAAGGCGCGGTTCGAGTTCCGCTGGCGCGACCAGTTCGCGCTCTCGCTCGACCCCGAGCGCGCGGAGGAGTACCACGA
CGAGACGCTCCCGGCCGAGGCCGCCAAGACCGCGCACTTCTGCTCGATGTGCGGGCCGAAGTTCTGCTCGATGCGCATCT
CGCAGGACATCCGCGAGGAGTTCGGCGGCGCCGAGCAGCAGGAGGCGATCGCCGGGATGGCGGCCAAGGCGGCCGAGTTC
CGCGCCGCCGGCGGCCAGGTCTACCTCCCTACCCCCACGGCGAGGTAG

Protein sequence :
MSHLAQSRALAFERDDESGICVPVTEISLAPSPDGTPNPPVRVYRTEGLGGDPTRGLPPQRSAWIEARGDTEVYEGRPHD
LADDGRGARRRGAASAEWRGERRPPRRAVPGRTVTQMHYARRGEVTPEMRFVALREGVDVELVRSEVAAGRAIIPANVNH
PESEPMIIGRAFTVKVNANIGNSAVHSSIAEEVEKLQWATRWGADTVMDLSTGDDIHTTREWILRNSPVPIGTVPVYQAL
EKVDGDASRLSWEVYRDTVIEQCEQGVDYMTVHAGVLLRYVPLTANRVTGIVSRGGSIMAGWCLAHHEENFLYTHFDELC
EIFARYDVAFSLGDGLRPGSLADANDAAQFAELDTLAELTKRAWEHDVQVMVEGPGHVPLHLVRENVERQQELCDGAPFY
TLGPLVTDIAPGYDHITSAIGATEIARYGTAMLCYVTPKEHLGLPNRDDVRTGVVTYKIAAHAADVAKGHPGARDRDDAL
SKARFEFRWRDQFALSLDPERAEEYHDETLPAEAAKTAHFCSMCGPKFCSMRISQDIREEFGGAEQQEAIAGMAAKAAEF
RAAGGQVYLPTPTAR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 3e-176 64
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 3e-176 64
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 3e-169 62