Gene Information

Name : Isova_2469 (Isova_2469)
Accession : YP_004543074.1
Strain : Isoptericola variabilis 225
Genome accession: NC_015588
Putative virulence/resistance : Resistance
Product : Cys/Met metabolism pyridoxal-phosphate-dependent protein
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : -
Position : 2701115 - 2702332 bp
Length : 1218 bp
Strand : -
Note : PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; KEGG: xce:Xcel_2638 cystathionine gamma-synthase

DNA sequence :
GTGACCCACCACGACGACTGGTCCACGACCGGCTTCTCGACCCGTGCCATCCACGCCGGGCAGGATCCCGACCCCACCAC
GGGCGCGGTCGTGCCCCCGATCCACCAGGTGTCCACGTACAAGCAGGACGGCGTGGGCGGGCTGCGCGGCGGCTACGAGT
ACTCGCGCTCCGCCAACCCCACCCGCACCGCGCTCGAGACCGCGATCGCGGCCGCCGAGACGCCGTCGGGTGCCGCGCCC
GCGCGCGGCTTCGCGTTCTCCTCGGGCCTCGCCGCGGAGGACACGTTCCTGCGCGCCGTGCTGCGCCCGGGTGACCACGT
GGTCATCCCCGACGACGCCTACGGTGGCTCGTACCGCCTTGTAGCACGGGTCTTCGGACCCTGGGGCGTCGACCACACCG
CGGTCGACCTCAGCGACCTCGACGCGGTCGAGGCGGCCCTCGTGCAGGGCCGCACGCGCGTGCTGTGGGTCGAGACGCCG
ACCAACCCGCTGCTCGGCGTCAGCGACATCGCCGCGCTGGCCGAGCTCGCGCACGCCGCCGGCGCGCTCCTGCTCGTCGA
CAACACGTTCGCCACGCCCTACCTCCAGCAGCCGATCGCGCTCGGTGCCGACGTCGTCGTGCACTCCACGACGAAGTACG
TCGGCGGGCACTCCGACGTCGTCGGCGGCGCGCTCGTCGTGGCCGACGGCGCCGCGATGCCCGGCGGTCTCCAGGCGCCC
GACGGCGGCACCTCGGTCGCCGACGCGGTCGCGTTCCACCAGAACTCGTCGGGGGCGGTGGCGGGCCCGTTCGACGCGTG
GCTCACGCTGCGCGGCCTGCGGACGCTGGGCGTGCGCATGGACCGGCACTGCGCCAACGCGCACGCCGTCGCCGGCTGGC
TCGAGCAGCACCCGCGGGTCGAGCAGGTGATCTACCCGGGCCTCGCGTCCCACCCGGGCCACGAGCTCGCGACCCGGCAG
ATGCGCGACTACGGCGGCATGGTCTCGTTCCGCGTGGGCAGCGAGGAGGCCGCGCTCGAGGTGTGCTCCCGCACGCGCGT
GTTCACGCTCGCCGAGTCGCTCGGCGGCGTCGAGTCGCTCATCGAGCACCCGGGGCGCATGACGCACGCGTCGGTCGCGG
GCTCGGCGCTCGAGGTCCCGTCGGACCTCGTGCGCCTGTCGGTCGGCATCGAGGACGTCGAGGACCTGCTCGCCGATCTC
GAGCGCGCGCTCGGCTGA

Protein sequence :
MTHHDDWSTTGFSTRAIHAGQDPDPTTGAVVPPIHQVSTYKQDGVGGLRGGYEYSRSANPTRTALETAIAAAETPSGAAP
ARGFAFSSGLAAEDTFLRAVLRPGDHVVIPDDAYGGSYRLVARVFGPWGVDHTAVDLSDLDAVEAALVQGRTRVLWVETP
TNPLLGVSDIAALAELAHAAGALLLVDNTFATPYLQQPIALGADVVVHSTTKYVGGHSDVVGGALVVADGAAMPGGLQAP
DGGTSVADAVAFHQNSSGAVAGPFDAWLTLRGLRTLGVRMDRHCANAHAVAGWLEQHPRVEQVIYPGLASHPGHELATRQ
MRDYGGMVSFRVGSEEAALEVCSRTRVFTLAESLGGVESLIEHPGRMTHASVAGSALEVPSDLVRLSVGIEDVEDLLADL
ERALG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 7e-57 44
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 8e-58 44
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 3e-44 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Isova_2469 YP_004543074.1 Cys/Met metabolism pyridoxal-phosphate-dependent protein BAC0207 Protein 3e-49 41